Prevalence of Androgen Deficiency in Men with Erectile Dysfunction

Köhler, Tobias; Kim, Johnny; Feia, Kendall; Bodie, Joshua; Johnson, Nick; Makhlouf, Antoine A.; Monga, Manoj

doi:10.1016/j.urology.2007.11.073

Cited by 77 publications

(45 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ED is seen with an age-stratified incidence of 1.9% at 40 years and 25% or greater by age 65 [2]. The reported incidence of endocrinopathy as the etiology of ED is 1-35% [3]. Interestingly, the prevalence of abnormally low serum T levels, even among men with ED, has historically been reported to be low (in urology *6%).…”

Section: Effects Of Testosterone Deficiency On Male Sexual Functionmentioning

confidence: 99%

Importance of hypogonadism and testosterone replacement therapy in current urologic practice: a review

Paduch

Donatucci

2010

Int Urol Nephrol

View full text Add to dashboard Cite

Evaluation of potential candidates for testosterone replacement therapy (TRT) includes a complete medical history, physical examination, and hormonal screening. The choice of testosterone assay is important in clinical decision making. TRT should, in theory, approximate natural endogenous production of the hormone. There is no apparent association between TRT and the development of prostate cancer. The administration of exogenous testosterone is not a means of reversing the aging process in men with normal testosterone levels, but it may offer considerable benefit for those with hypogonadism.

show abstract

Section: Effects Of Testosterone Deficiency On Male Sexual Functionmentioning

confidence: 99%

Importance of hypogonadism and testosterone replacement therapy in current urologic practice: a review

Paduch

Donatucci

2010

Int Urol Nephrol

View full text Add to dashboard Cite

show abstract

“…21 Testosterone has been proposed as another linking factor between ED and hypoxia, though it is controversial. Kö hler et al 22 reported that androgen deficiency was quite common in men with ED. Because sleep apnea is more prevalent in men and testosterone is known to affect sleep apnea and chemosensitivity, explaining why ED is more common in patients with OSAS based on testosterone levels alone is difficult.…”

Section: Erectile Dysfunction In Osas H-w Shin Et Almentioning

confidence: 99%

Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea

Han

et al. 2008

Int J Impot Res

View full text Add to dashboard Cite

Several reports have suggested a high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS). The aim of this study was to investigate the correlation between OSAS and ED, or disease-specific quality of life (QOL) in patients with OSAS. In addition, we analyzed specific polysomnographic (PSG) parameters in predicting ED in OSAS patients. In total, 32 patients with OSAS and 27 normal controls were asked to complete the Korean versions of the International Index of Erectile Function questionnaire (KIIEF-5) and the Calgary Sleep Apnea Quality of Life Index (SAQLI). All patients then underwent a full-night in-laboratory PSG examination. Patients were diagnosed with OSAS if they had clinical symptoms suggestive of OSAS for at least 1 year and an apnea-hypopnea index (AHI) of more than 10 in PSG. Nineteen patients (59.3%) in the OSAS group showed ED, which was significantly higher than in the control group (8 patients, 29.6%, P ¼ 0.012). In addition, SAQLI scores worsened as AHI increased (r ¼ 0.327, P ¼ 0.011) and as the lowest oxygen saturation level decreased (r ¼ 0.420, P ¼ 0.001). ED was not significantly correlated with AHI (r ¼ 0.061, P ¼ 0.649); however, it was significantly correlated with the lowest oxygen saturation decreased (r ¼ 0.338, P ¼ 0.009). When the cutoff value for the lowest oxygen saturation level to predict ED was set at 77%, its positive predictive value was 88.9% (sensitivity ¼ 0.70, specificity ¼ 0.62). Thus, all male patients with OSAS should be screened for erectile dysfunction and more comprehensive consultation is needed, especially, if their lowest oxygen saturation levels are below 77%.

show abstract

“…Een te laag testosterongehalte kan invloed hebben op ieder van de essentiële fysiologische processen die tot een erectie leiden, zoals de neuronale activiteit ten behoeve van de arteriële bloedtoevoer naar de penis, de relaxatie van de gladde spiercellen van de corpora cavernosa en de veno-occlusie [38]. Ook kan testosteron de initiatie van de erectie beïn-vloeden door de secretie van de hersenneurotransmitters te veranderen, zoals dopamine, oxytocine of NO van de mediale preoptische area [39].…”

Section: Testosteron En Edunclassified

Basaal wetenschappelijk bewijs voor de link tussen erectiele disfunctie en cardiometabole disfunctie

Leliefeld

2016

Tijdschr Urol

View full text Add to dashboard Cite

Prevalence of Androgen Deficiency in Men with Erectile Dysfunction

Cited by 77 publications

References 15 publications

Importance of hypogonadism and testosterone replacement therapy in current urologic practice: a review

Importance of hypogonadism and testosterone replacement therapy in current urologic practice: a review

Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea

Basaal wetenschappelijk bewijs voor de link tussen erectiele disfunctie en cardiometabole disfunctie

Contact Info

Product

Resources

About