Prevalence of Anemia 10 Years After Roux-en-Y Gastric Bypass in a Single Veterans Affairs Medical Center

Chen, Gao Linda; Kubat, Eric; Eisenberg, Dan

doi:10.1001/jamasurg.2017.3158

Cited by 10 publications

(6 citation statements)

References 6 publications

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“…Anemia is the most prevalent nutritional complication of bariatric procedures reported in the literature, occurring in as many as two-thirds of patients. 19,39 Indeed, in our study, postbariatric procedure hemoglobin levels in the overall cohort were significantly attenuated at all points and never recovered to prebariatric procedure levels. However, patients who underwent OAGB or LRYGB recorded a steeper decrease in hemoglobin during the first 3 months compared with those undergoing LSG, and hemoglobin levels remained statistically lower in the OAGB or LRYGB group than the LSG group for the rest of follow-up.…”

Section: Discussioncontrasting

confidence: 46%

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Associations of Bariatric Interventions With Micronutrient and Endocrine Disturbances

et al. 2020

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IMPORTANCE Few studies have described the longitudinal trajectories of serum levels of micronutrients whose deficiencies are associated with serious sequelae following bariatric procedures, such as anemia, osteoporotic fractures, and neuropathies. Furthermore, previous studies comparing laparoscopic sleeve gastrectomy (LSG) vs Roux-en-Y gastric bypass (LRYGB) or one-anastomosis gastric bypass (OAGB) procedures may have been limited by selection and confounding biases.OBJECTIVE To appraise the spectrum and temporal course of micronutrient deficiencies associated with bone metabolism and erythropoiesis after LSG vs OAGB or LRYGB procedures, using the propensity score as a balancing score.

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Section: Discussioncontrasting

confidence: 46%

“…Anemia is the most prevalent nutritional complication of bariatric procedures reported in the literature, occurring in as many as two-thirds of patients . Indeed, in our study, postbariatric procedure hemoglobin levels in the overall cohort were significantly attenuated at all points and never recovered to prebariatric procedure levels.…”

Section: Discussioncontrasting

confidence: 43%

Associations of Bariatric Interventions With Micronutrient and Endocrine Disturbances

et al. 2020

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“…To further complicate matters, the prevalence of other micronutrient deficiencies is increasing, and major limitations of perioperative nutritional care are common, including lack of preoperative screening, failure to provide supplements, poor patient compliance with supplementation, patient reluctance to take iron supplements because of unpleasant gastrointestinal side effects, major gaps in surgical and nutritional follow‐up, and lack of specialized nutritional care after surgery . Considered together, these findings reflect a growing problem and an opportunity for quality improvement in metabolic surgery.…”

Section: Factors Contributing To Postoperative Iron Deficiencymentioning

confidence: 99%

“…Programmes must improve patient follow‐up after surgery and provide ongoing specialized nutritional surveillance within the follow‐up programme. Regular follow‐up and specialized care in the bariatric programme have been shown to reduce the prevalence of anaemia 10 years after metabolic surgery . Preliminary evidence suggests that long‐term nutritional care in the metabolic surgery programme is superior to care provided by primary care providers with outside specialists …”

Section: Potential Strategies For Treatment and Preventionmentioning

confidence: 99%

Metabolic surgery and iron homeostasis

et al. 2018

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Iron deficiency and anaemia after metabolic surgery, potentially modifiable nutritional complications, are becoming an increasing cause for concern as prevalence increases with time and there is limited evidence supporting the effectiveness of the current guidelines for prophylactic oral iron supplementation and treatment for deficiency.Abnormalities in iron nutrition predisposing to deficiency are common in severely obese patients, and the low-grade systemic inflammation, also common to these patients, reduces the effectiveness of oral iron supplementation. The surgical procedures result in alterations of foregut anatomy and physiology, which limit iron absorptive capacity and daily food intake. These alterations and the limited effects of oral iron supplementation explain the high prevalence of postoperative iron deficiency and anaemia. This review outlines current mechanisms concerning the pathogenesis of disordered iron nutrition in patients with severe obesity, current gaps in knowledge, and opportunities for quality improvement.

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“…In France, 5% of patients were diagnosed with anemia after bariatric surgery between 2008 and 2016[ 11 ]. Additionally, if a patient did not receive an outpatient follow-up, the prevalence of anemia could even be 57% 10 years after Roux-en-Y gastric bypass[ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Risk of anemia in morbidly obese patients after bariatric surgery in Taiwan

Wang

Hsieh²,

Chen

2020

WJD

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BACKGROUND Bariatric surgery is one of most effective long-term treatments for morbid obesity. However, post-bariatric surgery anemia is identified as a common adverse effect and remains a challenge nowadays. AIM To estimate the risk of post-bariatric surgery anemia and to stratify the association between age, gender, and types of surgery. METHODS This study is a population-based cohort study. We conducted this nationwide study using claims data from National Health Insurance Research Database in Taiwan. There were 4373 morbidly obese patients in this study cohort. RESULTS Among patients who were diagnosed with morbid obesity, 2864 received bariatric surgery. All obesity-associated comorbidities decreased in the surgical group. Increasing risk of post-bariatric surgery anemia among obese patients was found by Cox proportional hazards regression [adjusted hazard ratio (HR): 2.36]. Also, we found significantly increasing cumulative incidence rate of anemia among patients receiving bariatric surgery by log-rank test. After adjusting for age and gender, the increasing incidence of post-bariatric surgery anemia was found among women (adjusted HR: 2.48), patients in the 20–29-year-old group (adjusted HR: 3.83), and patients in the 30-64-year-old group (adjusted HR: 2.37). Moreover, malabsorptive and restrictive procedures had significantly higher adjusted HRs, 3.18 and 1.55, respectively. CONCLUSION Bariatric surgery give rise to anemia risk among obese patients, specifically in women, young- and middle-aged patients, and patients undergoing malabsorptive procedures in our population-based cohort study in Taiwan.

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Prevalence of Anemia 10 Years After Roux-en-Y Gastric Bypass in a Single Veterans Affairs Medical Center

Cited by 10 publications

References 6 publications

Associations of Bariatric Interventions With Micronutrient and Endocrine Disturbances

Associations of Bariatric Interventions With Micronutrient and Endocrine Disturbances

Metabolic surgery and iron homeostasis

Risk of anemia in morbidly obese patients after bariatric surgery in Taiwan

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