Prevalence of anemia among children in India and updated serum ferritin levels

Ahmed, H Shafeeq

doi:10.1002/pbc.29704

Cited by 1 publication

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“…As we know, SF, sTfR and CRP [ 23 , 24 , 25 ] can be used to judge the iron level, PA [ 26 ] can be used to judge the protein level, RBP4 [ 27 ] can be used to judge the VA level, ApoB [ 28 ] and D-D [ 29 ] can be used to reflect the risk of cardiovascular and cerebrovascular disease, AFP [ 30 ] is a marker of liver cancer development and progression, and CEA [ 31 ] is a preferred indicator of colon-cancer staging studies before surgical resection. The system error of the conventionally separate detection for each indicator above might disturb the correct analysis for the relationship among the nine protein markers.…”

Section: Discussionmentioning

confidence: 99%

Construction and Evaluation of a Novel MAP Immunoassay for 9 Nutrition-and-Health-Related Protein Markers Based on Multiplex Liquid Protein Chip Technique

et al. 2023

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We attempted to construct and evaluate a novel detection method to realize simultaneous detection based on a multiplex liquid protein chip technique for nine nutrition-and-health-related protein markers to meet the requirement of an accurate, simultaneous and comprehensive analysis of the proteomics of nutrition and health. The lower limits of detection, biological limits of detection and regression equations of serum ferritin (SF), soluble transferrin receptor (sTfR), c-reactive protein (CRP), retinol-binding protein4 (RBP4), apolipoprotein B (ApoB), alpha-fetoprotein (AFP), prealbumin (PA), carcino-embryonic antigen (CEA) and D-Dimmer (D-D) were determined after a series of optimal experiments. Then, the results of the methodological evaluation for this novel method indicated that the accuracies were between 70.12% and 127.07%, the within-run precisions were between 0.85% and 7.31%, the between-run precisions were between 3.53% and 19.07%, the correlation coefficients between this method and other methods were above 0.504 (p < 0.05), and the direct bilirubin (DBIL) of low concentration and the indirect bilirubin (IBIL) of high concentration could not interfere with the detected results of nine indicators. The novel multiplex detection method, which can increase accuracy and improve the ability of comprehensive analysis, can basically meet the requirement of detection and the diagnosis of the proteomics of nutrition and health.

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Section: Discussionmentioning

confidence: 99%