Prevalence of Anginal Symptoms and Myocardial Ischemia and Their Effect on Clinical Outcomes in Outpatients With Stable Coronary Artery Disease

Effects of Ranolazine on Angina and Quality of Life After Percutaneous Coronary Intervention With Incomplete Revascularization

“…Those with both angina and ischemia in The Prospective Observational Longitudinal Registry of Patients with Stable Coronary Artery Disease (CLARIFY) population were more frequently younger, female, with heart failure, and diabetes mellitus than those with either angina or ischemia alone. 37 Symptoms of angina may arise from obstructive coronary disease (including ICR following PCI), microvascular dysfunction, or a mismatch in supply and demand, all with varying degrees of associated ischemia. Therefore, targeting a population with angina that is reflective of ischemia in the absence of confirmative diagnostic tests, is an important challenge (as well as limitation) for chronic studies evaluating ICR.…”

Differences in outcomes in patients with stable coronary artery disease managed by cardiologists versus non-cardiologists: the international prospective CLARIFY registry

“…[15][16][17][18][19] Thus, the differences in management patterns in our study, both recorded and unrecorded, might have been responsible for the better outcomes in patients managed by cardiologists. The second potential explanation is intrinsic differences between the groups.…”

Myocardial perfusion imaging prior to coronary revascularization: From risk stratification to procedure guidance

“…2 Furthermore, obstructive CAD is a frequent cause of angina which may limit quality of life. 3 In patients with stable CAD, coronary revascularization may be pursued to (1) decrease angina and improve quality of life, and/or (2) to prolong life and prevent downstream hard cardiovascular events such as myocardial infarction. The role of coronary revascularization in patients with obstructive but stable CAD, and how best to perform it, is a topic of ongoing debate and research.…”