Prevalence of antenatal depression and associated factors of continuous three trimesters depression: A multicentre study in Chengdu, China

Abstract

Background Antenatal depression (AD) is a major depressive disorder during pregnancy, which may lead to devastating sequelae for the expectant mothers and infants. This study aims to investigate the prevalence of (AD), and to explore influence factors of AD among pregnant women of continuous three trimesters in Chengdu, China. Methods The prospective study included pregnant women who were in their first, second and third trimester pregnancy and were recruited from four maternity hospitals by using the method of stratified and convenient sampling from March 2019 to May 2020 in Chengdu, China. These women completed questionnaires that included the Chinese validated versions of the Edinburgh Postnatal Depression Scale (EPDS) and questions related to health status, cognition, and soci-demographic variables to measure AD. The chi-square test and multivariate binary logistic regression was used to analyze. Results A total of 4560 pregnant women were recruited, 1051 women completed the whole study. The prevalence of depression symptoms during the first, second and third trimesters were 32.92% (346/1051), 19.79% (208/1051) and 20.46% (215/1051), respectively. During all stages group depression (77), the relations with parents-in-law, the marital relationship, and recent major negative life events, fear about dystocia and taking care of baby were the independent influencing factors of the depression (P < 0.05) compared with no risk depression group (571). The marital relationship, and recent major negative life events, fear about dystocia and the father desired sex of the baby (male) were the independent influencing factors of the depression (P < 0.05) compared with the depression of any one trimester (268). The father desired sex of the baby (male) was the independent influencing factors of the depression (P < 0.05) compared with the depression of any two stages (135). Conclusion The incidence and levels of depression in the first trimester of pregnancy are the highest. Therefore, it’s important to focus on the psychological status of pregnant women, especially the first trimester. The study suggested it’s necessary to establish a good marital relationship, to have the confidence of childbirth, and change the attitude of the father desired sex of the baby (male).

Comparison between acupuncture and antidepressant therapy for the treatment of poststroke depression

“…Details of the literature search and screening process are presented in Figure 1. After sufficient screening, 14 studies met criteria and were included in the final analysis [12,17–29] . The main features of the included trials are summarized in Table 2.…”

“…Utilizing the Jadad score form, the methodological quality of the included trials was assessed, and is shown in Table 2. All 14 studies [12,17–29] received ≥3 points and were included in the meta-analysis.…”

“…Thirteen RCTs [12,17,19–29] utilized a HAMD score to evaluate the efficacy of treatment at weeks 3, 4, 6, and 8 (Figs. 3–6).…”

“…3–6). Two RCTs, [21,22] representing 140 patients measured HAMD score at week 3. Pooled data from these studies showed that acupuncture more dramatically decreased HAMD scores when compared to antidepressants (MD = −1.17, 95%CI = −2.18 to −0.16, P = .02, I 2 = 0%), with no heterogeneity observed in the fixed-effects models.…”

“…Acupuncture was significantly associated with increasing total clinical efficacy compared to antidepressants (RR = 1.15, 95%CI = 1.08–1.21, P < .00001, I 2 = 24%), with no heterogeneity in the fixed-effects models, which involved 12 RCTs, [12,17,18,21–29] including 1010 patients (Fig. 9 A ).…”