Prevalence of Antimicrobial Resistance in Escherichia coli and Salmonella Species Isolates from Chickens in Live Bird Markets and Boot Swabs from Layer Farms in Timor-Leste

Pereira, Abrao; Sidjabat, Hanna E.; Davis, Steven; Vong da Silva, Paulo Gabriel; Alves, Amalia; Dos Santos, Cristibela; Jong, Joanita Bendita da Costa; da Conceição, Felisiano; Felipe, Natalino de Jesus; Ximenes, Augusta; Nunes, Junilia; Fária, Isménia do Rosário; Lopes, Isabel; Barnes, Tamsin S.; McKenzie, Joanna; Oakley, Tessa; Francis, Joshua R.; Yan, Jennifer; Ting, Shawn

doi:10.3390/antibiotics13020120

Cited by 2 publications

(1 citation statement)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In layer farms and commercial eggs from Central-Western Brazil, the occurrence of MDR Salmonella serovars such as Agona, Salmonella enterica subspecies enterica O:4.5, and Schwarzengrund may pose a public health risk [42,73]. Our study contributes valuable data on resistance profiles and MDR Salmonella in chickens, identifying multiple resistances to third-generation cephalosporins and fluoroquinolones, deemed "critically important antibiotics" (CIA).…”

Section: Discussionmentioning

confidence: 93%

Antibiotic Resistance Profile of Salmonella sp. Isolates from Commercial Laying Hen Farms in Central-Western Brazil

Moraes,

Almeida,

Andrade

et al. 2024

Microorganisms

View full text Add to dashboard Cite

Microbial resistance to antibiotics poses a significant threat to both human and animal health, necessitating international efforts to mitigate this issue. This study aimed to assess the resistance profiles of Salmonella sp. isolates and identify the presence of intl1, sul1, and blaTEM resistance genes within antigenically characterized isolates, including Agona, Livingstone, Cerro, Schwarzengrund, Salmonella enterica subsp. enterica serotype O:4.5, Anatum, Enteritidis, Johannesburg, Corvallis, and Senftenberg. These isolates underwent susceptibility testing against 14 antibiotics. The highest resistance percentages were noted for sulfamethoxazole (91%), sulfonamides (51%), and ceftiofur (28.9%), while no resistance was observed for ciprofloxacin. Salmonella Johannesburg and Salmonella Corvallis showed resistance to one antibiotic, whereas other serovars were resistant to at least two. Salmonella Schwarzengrund exhibited resistance to 13 antibiotics. The intl1 gene was detected in six out of the ten serovars, and the sul1 gene in three, always co-occurring with intl1. The blaTEM gene was not identified. Our findings highlight the risk posed by the detected multiple resistances and genes to animal, human, and environmental health. The multidrug resistance, especially to third-generation cephalosporins and fluoroquinolones, highlights the need for stringent monitoring of Salmonella in laying hens. The potential of the environment, humans, eggs, and their products to act as vectors for antibiotic resistance represents a significant concern for One Health.

show abstract

Section: Discussionmentioning

confidence: 93%

Antibiotic Resistance Profile of Salmonella sp. Isolates from Commercial Laying Hen Farms in Central-Western Brazil

Moraes,

Almeida,

Andrade

et al. 2024

Microorganisms

View full text Add to dashboard Cite

show abstract

Association between antimicrobial usage and resistance on commercial broiler and layer farms in Bangladesh

Foysal,

Imam,

Das

et al. 2024

Front. Vet. Sci.

View full text Add to dashboard Cite

Antimicrobial resistance has emerged as a significant health problem worldwide, including in Bangladesh, where chickens are an important protein source for human nutrition. One of the factors accelerating the development of antimicrobial resistance is the inappropriate use of antimicrobials on commercial chicken farms. A cross-sectional study was conducted in 2019 on 140 commercial chicken farms in the Chattogram district of Bangladesh to investigate the association between antimicrobial use and resistance in Escherichia coli and Salmonella spp. cultured from cloacal swabs of chickens and from the poultry shed environment. All E. coli and Salmonella spp. isolates were resistant to multiple antimicrobial classes, including those categorized as “Highest Priority Critically Important Antimicrobials” for human medicine. Notably, resistance was observed in E. coli isolates from farms that did not use these antimicrobial classes in the current production cycle. For example, although quinolones were not used on 43.9% of E. coli positive farms, 95.7% of these farms had quinolone-resistant E. coli isolates. The results of the path analysis revealed that there was a “direct effect” of the frequency of antimicrobial usage on “high” resistance, with resistance increasing when antimicrobials were administered more frequently (β = 0.28, p = 0.002). There was a “direct effect” of the purpose of antimicrobial use on “low” resistance, with resistance marginally decreasing when antimicrobials were administered solely for therapeutic use (β = −0.17, p = 0.062), but increasing when they were used prophylactically. Overall, the study results could be used to educate farmers on better practices for antimicrobial administration, and to guide government agencies to update policies on antimicrobial use and resistance surveillance in the poultry sector of Bangladesh.

show abstract

Prevalence of Antimicrobial Resistance in Escherichia coli and Salmonella Species Isolates from Chickens in Live Bird Markets and Boot Swabs from Layer Farms in Timor-Leste

Cited by 2 publications

References 79 publications

Antibiotic Resistance Profile of Salmonella sp. Isolates from Commercial Laying Hen Farms in Central-Western Brazil

Antibiotic Resistance Profile of Salmonella sp. Isolates from Commercial Laying Hen Farms in Central-Western Brazil

Association between antimicrobial usage and resistance on commercial broiler and layer farms in Bangladesh

Contact Info

Product

Resources

About