Prevalence of anxiety and depression symptoms in pregnant women with type 2 diabetes and the impact on glycaemic control

Àsbjörnsdóttir, Björg; Vestgaard, Marianne; Callesen, Nicoline; Ringholm, Lene; Andersen, Lise Lotte Torvin; Jensen, Dorte Møller; Damm, Peter; Mathiesen, Elisabeth R.

doi:10.1111/dme.14506

Cited by 16 publications

(11 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Overall, the results indicated high prevalence rates of both anxiety and depression among pregnant women with diabetes (irrespective of type). These ndings are consistent with previous literature [10,13,14,[30][31][32][33] although prevalence rates differ among different populations.…”

Section: Discussionsupporting

confidence: 93%

“…Also, based on a recent meta-analytic review, the pooled prevalence of anxiety disorders among pregnant mothers with GDM was 9% and was not statistically signi cant among individuals from Black, Asian and Minority ethnic backgrounds [10]. Using the HADS, Ásbjörnsdóttir et al reported a 40% prevalence rate for anxiety and/or depression symptoms in early pregnancy among women with type 2 diabetes compared to 7% among pregnant women without diabetes [31]. Also using the HADS, Do et al reported a prevalence of 22% and 17% anxiety in early and late pregnancy among 137 pregnant women with type 1 or type 2 diabetes [32].…”

Section: Discussionmentioning

confidence: 99%

“…One reason might be the difference in the psychometric scales used to assess anxiety and depression symptoms such as the Pregnancy-related Anxiety Scale [13], the HADS [31,32], or the 21-item Depression and Anxiety Scale (DASS-21) [30]. Differences in items, scoring, and interpretation might be a possible source of heterogeneity.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of anxiety and depression among pregnant women with diabetes and their predictors in Qazvin province, Iran

Salimi,

Griffiths,

Alimoradi

2023

Preprint

View full text Add to dashboard Cite

Background: Addressing mental health of diabetic pregnant women is important as it might increase the chance of obstetric complications, preterm birth, and neonatal complications. Aim: The present study investigated the prevalence of anxiety and depression among pregnant women with diabetes and their predictors. Methods: A cross-sectional study was conducted in 2023. The sample comprised 350 pregnant women with diabetes (pre-pregnancy or gestational) referred to comprehensive health centers in Qazvin Province, Iran. Fertility and demographic characteristics, anxiety, depression, partner social support, self-efficacy, medication adherence and fear of hypoglycemia were assessed. Results: Among the sample, 28.9% had pre-pregnancy diabetes and 71.1% had gestational diabetes. Anxiety and depression were reported by 74.9% and 79.4% of all participants (significantly higher among those with pre-existing diabetes compared to gestational diabetes). Self-efficacy (OR: 0.91 [95% CI: 0.86; 0.96]) and spouse's social support (OR: 0.68 [95% CI: 0.56; 0.82]) were significant predictors of abnormal anxiety. Fear of hypoglycemia (OR: 1.06 [95% CI: 1.02; 1.09]), medication adherence (OR: 1.05 [95% CI: 1.01; 1.09]), self-efficacy (OR: 0.86 [95% CI: 0.82; 0.91]), partner social support (OR: 0.62 [95% CI: 0.49; 0.78]), diabetes type (pregnancy vs. pre-pregnancy diabetes; OR: 0.26 [95% CI: 0.09; 0.77]), perceived family economic status (fair vs. good; OR: 3.08 [95% CI: 1.12; 8.49]), and diabetes treatment (insulin vs. diet; OR: 0.21 [95% CI: 0.08; 0.55]) were significant predictors of abnormal depression. Conclusion: Diabetic pregnant women should be evaluated for anxiety and depression during their prenatal visit. Improving self-efficacy, increasing medication adherence, reducing the fear of hypoglycemia, and improving the spouse’s social support might all be helpful in reducing anxiety and depression among pregnant women with diabetes.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of anxiety and depression among pregnant women with diabetes and their predictors in Qazvin province, Iran

Salimi,

Griffiths,

Alimoradi

2023

Preprint

View full text Add to dashboard Cite

show abstract

“…The level of hyperglycemia on oral glucose tolerance testing has been correlated to mood in women with gestational diabetes (11), and women with type 2 diabetes and symptoms of anxiety or depression have shown higher HbA 1c in late pregnancy than those without (12).…”

Section: Discussionmentioning

confidence: 99%

Mental Health During Late Pregnancy and Postpartum in Mothers With and Without Type 1 Diabetes: The ENDIA Study

et al. 2022

View full text Add to dashboard Cite

OBJECTIVE Pregnancy and type 1 diabetes are each associated with increased anxiety and depression, but the combined impact on well-being is unresolved. We compared the mental health of women with and without type 1 diabetes during pregnancy and postpartum and examined the relationship between mental health and glycemic control. RESEARCH DESIGN AND METHODS Participants were women enrolled from 2016 to 2020 in the Environmental Determinants of Islet Autoimmunity (ENDIA) study, a pregnancy to birth prospective cohort following children with a first-degree relative with type 1 diabetes. Edinburgh Postnatal Depression Scale (EPDS) and Perceived Stress Scale (PSS) were completed during the third trimester (T3) (median [interquartile range] 34 [32, 36] weeks) and postpartum (14 [13, 16] weeks) by 737 women (800 pregnancies) with (n = 518) and without (n = 282) type 1 diabetes. RESULTS EPDS and PSS scores did not differ between women with and without type 1 diabetes during T3 and postpartum. EPDS scores were marginally higher in T3: predicted mean (95% CI) 5.7 (5.4, 6.1) than postpartum: 5.3 (5.0, 5.6), independent of type 1 diabetes status (P = 0.01). HbA1c levels in type 1 diabetes were 6.3% [5.8, 6.9%] in T3 and did not correlate with EPDS or PSS scores. Reported use of psychotropic medications was similar in women with (n = 44 of 518 [8%]) and without type 1 diabetes (n = 17 of 282 [6%]), as was their amount of physical activity. CONCLUSIONS Overall, mental health in late pregnancy and postpartum did not differ between women with and without type 1 diabetes, and mental health scores were not correlated with glycemic control.

show abstract

“…Moreover, among pregnant women without diabetes and non-pregnant people with diabetes, modifiable characteristics such as health behaviours (eg, comfort eating, sedentary behaviour, smoking, alcohol use, poor sleep, limited self-monitoring) and psychological distress, particularly pregnancy-related and diabetes-related distress, have been linked to adverse pregnancy and diabetes outcomes 31–34. However, few studies in pregnant women with pre-existing diabetes have examined the role of health behaviours and psychological distress in relation to adverse outcomes 35–41. Moreover, potential mechanisms and the role of partner support have not been explored in this group.…”

Section: Introductionmentioning

confidence: 99%

Danish Diabetes Birth Registry 2: a study protocol of a national prospective cohort study to monitor outcomes of pregnancies of women with pre-existing diabetes

Knorr,

Aalders,

Overgaard

et al. 2024

BMJ Open

Self Cite

View full text Add to dashboard Cite

IntroductionDespite technological developments and intensified care, pregnancies in women with pre-existing diabetes are still considered high-risk pregnancies. The rate of adverse outcomes in pregnancies affected by diabetes in Denmark is currently unknown, and there is a limited understanding of mechanisms contributing to this elevated risk. To address these gaps, the Danish Diabetes Birth Registry 2 (DDBR2) was established. The aims of this registry are to evaluate maternal and fetal-neonatal outcomes based on 5 years cohort data, and to identify pathophysiology and risk factors associated with short-term and long-term outcomes of pregnancies in women with pre-existing diabetes.Methods and analysisThe DDBR2 registry is a nationwide 5-year prospective cohort with an inclusion period from February 2023 to February 2028 of pregnancies in women with all types of pre-existing diabetes and includes registry, clinical and questionnaire data and biological samples of mother–partner–child trios. Eligible families (parents age ≥18 years and sufficient proficiency in Danish or English) can participate by either (1) basic level data obtained from medical records (mother and child) and questionnaires (partner) or (2) basic level data and additional data which includes questionnaires (mother and partner) and blood samples (all). The primary maternal outcome is Hemoglobin A1c (HbA1c) levels at the end of pregnancy and the primary offspring endpoint is the birth weight SD score. The DDBR2 registry will be complemented by genetic, epigenetic and metabolomic data as well as a biobank for future research, and the cohort will be followed through data from national databases to illuminate possible mechanisms that link maternal diabetes and other parental factors to a possible increased risk of adverse long-term child outcomes.Ethics and disseminationApproval from the Ethical Committee is obtained (S-20220039). Findings will be sought published in international scientific journals and shared among the participating hospitals and policymakers.Trial registration numberNCT05678543.

show abstract

Prevalence of anxiety and depression symptoms in pregnant women with type 2 diabetes and the impact on glycaemic control

Cited by 16 publications

References 30 publications

Prevalence of anxiety and depression among pregnant women with diabetes and their predictors in Qazvin province, Iran

Prevalence of anxiety and depression among pregnant women with diabetes and their predictors in Qazvin province, Iran

Mental Health During Late Pregnancy and Postpartum in Mothers With and Without Type 1 Diabetes: The ENDIA Study

Danish Diabetes Birth Registry 2: a study protocol of a national prospective cohort study to monitor outcomes of pregnancies of women with pre-existing diabetes

Contact Info

Product

Resources

About