Prevalence of arterial hypertension and the number and classes of antihypertensive drugs prescribed for patients late after kidney transplantation

Kurnatowska, Ilona; Królikowski, Jerzy; Jesionowska, Kinga; Marczak, Anna; Krajewska, Joanna; Zbróg, Zbigniew; Nowicki, Michał

doi:10.12659/aot.882636

Cited by 13 publications

(1 citation statement)

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“…Based on the available literature, approximately 70% to 90% of patients after kidney transplantation suffer from hypertension [1], among whom 34.2% require the concomitant implementation of three antihypertensive agents, while 30.6% necessitate the simultaneous use of four or more antihypertensive drugs. Notably, treatment resistance is observed in approximately 20% of the recipient population [2], out of which a noteworthy number of patients are diagnosed with refractory hypertension characterized by the blood pressure remaining uncontrolled despite the use of ≥5 antihypertensive agents of different classes at their recommended doses [3].…”

Section: Introductionmentioning

confidence: 99%

Native Renal Arteries Denervation as a Therapy of Refractory Hypertension in Patient after Heart and Kidney Transplantation—5 Years of Observation

Pilch,

Mizera,

Wiśnicki

et al. 2023

JCM

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This case report describes a 59-year-old male patient after heart and kidney transplantation, subsequently diagnosed with refractory hypertension since implemented antihypertensive pharmacotherapy consisting of six agents did not provide a substantial therapeutic response. Elevated blood pressure and its impact on a hypertrophied transplanted heart and impaired renal graft function have led to a significant deterioration in the patient’s cardiovascular risk profile. To address this issue, a native renal arteries denervation was performed. It resulted in a noteworthy decrease in both systolic and diastolic pressure values, thus manifesting a positive hypotensive effect. Furthermore, a sustainable reduction of left ventricular mass and stabilization in kidney graft function were noticed. The presented case provides evidence that renal denervation can be an efficacious complementary treatment method in individuals who received kidney and heart grafts as it leads to a decrease in cardiovascular risk.

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Section: Introductionmentioning

confidence: 99%