Prevalence of Beta-hemolytic Streptococcus Carrier State and its Sensitivity to Different Antibiotics among Guidance - School Children in Kerman-Iran

Abstract

Group A -hemolytic streptococcus is the most frequently isolated pathogen in acute pharyngitis and pharingotonsilits Cases in school -aged children. Resulting in dangerous complications such as rheumatic fever and glomerulonephritis, diagnosis and treatment of the disease would be of great importance. The aim of this study was determination of the frequency of group Ahemolytic streptococcus carriers in middle school in Kerman. A total of 200 students with ages ranging from 11 to 15 years were included in the study. The inclusion criteria were having no symptoms or signs of upper respiratory tract infection, and no antibiotics usage in the last two weeks. The overall prevalence of group A -hemolytic streptococcus carrier state in all age groups was 28.5%. After doing antibiogram test, all of them were sensitive to vancomycin, erythromycin and cephalotin and reversely resistant to penicillin. Our study suggests that inappropriate use of these antibiotics increases the chronic carrier state of Group A -hemolytic streptococcus in our community.

The Prevalence of Group A Streptococci Carriers Among Asymptomatic School Children

“…The healthy carriers of GAS are the sources of a bacterial dissemination and they are able to communicate the disease and even lead to severe epidemics [5]. According to different studies, GAS is seen more in the pharynges of children as compared to that in adults [5].…”

“…The healthy carriers of GAS are the sources of a bacterial dissemination and they are able to communicate the disease and even lead to severe epidemics [5]. According to different studies, GAS is seen more in the pharynges of children as compared to that in adults [5]. In the present study, Beta Haemolytic Streptococci (BHS) were isolated from 44 (2.2%) children, which was less than those which were isolated in other studies [3,[6][7][8].…”

The prevalence and antimicrobial susceptibility patterns of beta-hemolytic streptococci colonizing the throats of schoolchildren in Assam, India

“…There have been reports of emerging antimicrobial drug resistant strains among the βhemolytic streptococci (BHS). Most alarming would be an increase in resistance to the older, most effective and less expensive antibiotics, such as penicillin [11][12][13]. Streptococci can be transmitted from person to person via aerosols after sneezing or coughing, and also via fomites.…”

Asymptomatic pharyngeal carriage rate of Streptococcus pyogenes, its associated factors and antibiotic susceptibility pattern among school children in Hawassa town, southern Ethiopia

“…An educational status, employment status of the family, separation of mother and father (6), sex (7)(8)(9)(10), socioeconomic and environmental factors, lack of awareness of disease transmission are the risk factor for colonization of the S. pyogenes among school children. (11,12).…”

“…GAS has not been developed resistance to any of the penicillin's over the last decades. Nowadays, it is starting to appear antimicrobial drug resistant strain from asymptomatic children (13) including penicillin (6). However, in Ethiopia, antimicrobial resistance pattern to the GAS isolated from throat/phyeranax were not adequately explicated.…”