Prevalence of bladder, bowel and sexual problems among multiple sclerosis                 patients two to five years after diagnosis

Nortvedt, Monica Wammen; Riise, Trond; Frugård, Jannicke; Mohn, J; Bakke, August; Skår, Anne Br; Nyland, Harald; Glad, S.; Myhr, Kjell–Morten

doi:10.1177/1352458506071210

Cited by 224 publications

(207 citation statements)

References 26 publications

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“…The prevalence of constipation and/or FI among MS patients ranges from 20% to 73%. 9,10 A similar high occurrence of FI ranging from 30% to 50% has been reported in Parkinson's disease (PD) patients. There is little doubt that NBD affects both the physical and psychological aspects of quality of life and its early recognition and management are vital.…”

supporting

confidence: 60%

Evaluation and Treatment of Neurogenic Bowel Dysfunction – A Review

Kumar¹,

Athanasakos²,

Emmanuel³

2016

European Neurological Review

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Neurogenic bowel dysfunction is a severely troubling entity for patients with neurological disease or injury. The complex symptom cluster presents a challenge, not only for the patients but also for the treating clinician. Without intervention, patients are bound to have a reduced quality of life, and experience social impacts and secondary complications that come along with it. A careful initial assessment provides an idea of symptom severity and is crucial for successful rehabilitation. The mainstay of treatment remains a conservative approach of managing faecal incontinence or optimising the mechanics of defecation to improve patient’s quality of life. This article attempts to provide a comprehensive review of existing literature on pathophysiology, assessment and management of neurogenic bowel dysfunction.

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supporting

confidence: 60%

Evaluation and Treatment of Neurogenic Bowel Dysfunction – A Review

Kumar¹,

Athanasakos²,

Emmanuel³

2016

European Neurological Review

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“…For example, extensive literature has documented that vesicourethral and bladder dysfunctions, such as incomplete emptying, which are closely linked to risk of urinary tract infection, 17 have an increased prevalence in patients with MS. 18,19 In addition, patients with…”

Section: Discussionmentioning

confidence: 99%

Multiple Sclerosis and Risk of Infection-Related Hospitalization and Death in US Veterans

Nelson¹,

Xie²,

DuVall³

et al. 2015

International Journal of MS Care

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Background: This study estimated the risk of infection-related hospitalizations and death in patients with and without multiple sclerosis (MS). Methods: We identified adults with MS in the US Department of Veterans Affairs (VA) system between 1999 and 2010. Each veteran with MS was matched, on age and sex, with up to four veterans without MS. Multivariable Cox proportional hazards regression models were performed to assess the influence of MS on the development of serious and fatal infections. Results: The cohort included 7743 veterans with MS and 30,972 veterans without MS. Mean (SD) age was 53.8 (13.3) years, and 80.8% were male. The incidence per 1000 person-years of overall serious infections was 19.2 (95% confidence interval [CI], 17.6–20.8) for those with MS and 10.3 (95% CI, 9.8–10.9) for those without MS. Fatal infection incidence rates were 1.2 (95% CI, 0.8–1.7) for patients with MS and 0.5 (95% CI, 0.3–0.6) for patients without MS. Regression models showed that veterans with MS were at greater risk for overall serious (hazard ratio [HR] = 1.52, P < .01) and fatal (HR = 1.85, P = .03) infections and serious respiratory (HR = 1.31, P = .01), urinary tract (HR = 4.44, P < .01), and sepsis-related infections (HR = 2.56, P < .01). Conclusions: This study provides evidence that VA patients with MS are more likely than those without MS to be hospitalized and die of infection.

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“…1 MS patients frequently suffer from urinary complaints. [2][3][4] De Seze and colleagues 5 report a prevalence of 37-99% for overactive bladder syndromes, characterized by irritative bladder symptoms, a prevalence of 34-79% for obstructive symptoms and 25% for chronic urinary retention.…”

Section: Introductionmentioning

confidence: 99%

Overactive bladder symptoms in patients with multiple sclerosis: Frequency, severity, diagnosis and treatment

Akkoç

Ersöz²,

Yüceyar

et al. 2016

The Journal of Spinal Cord Medicine

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Objective: To determine the frequency and severity as well as the diagnosis and treatment of overactive bladder problems in patients with multiple sclerosis (MS) followed up at five centers in Turkey. Design: Survey study. Setting: Outpatient tertiary clinics of physical medicine and rehabilitation and neurology. Participants: Consecutive MS patients scheduled for outpatient follow-up (n = 309). Intervention: MS patients were asked to complete a questionnaire regarding the frequency and severity, as well as the diagnosis and treatment of their overactive bladder problems. Results: The mean age ± SD was 39.3 ± 10.6 years. Urinary urgency was the most common urinary symptom (62%), followed by frequency (50.4%), urge incontinence (44.7%) and nocturia (33%). Residual urine volume was measured using a portable ultrasound instrument in 13.3% of the patients and by catheterization in 16.2% of them. Urodynamic investigations and urinary tract ultrasound were performed on 26.5% and 35.3% of the patients, respectively. Anticholinergic medications were prescribed for 27.5% of the patients. Intermittent catheterization and indwelling catheterization were used on 8.1% and 1.9% of the patients, respectively. The overactive bladder symptom score (OABSS) was significantly higher in patients who had had residual urine measurement (P < 0.001), upper urinary tract assessment by ultrasound (P < 0.001), urodynamic assessment (P < 0.001), admitted to a doctor for urinary symptoms (P < 0.001), and current or past catheter use (P = 0.002). Conclusion: Urgency was the most common urinary symptom followed by frequency, urge incontinence and nocturia in MS patients. The patients with lower OABSS had detailed urological assessments less frequently than the patients with higher OABSS.

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Prevalence of bladder, bowel and sexual problems among multiple sclerosis patients two to five years after diagnosis

Cited by 224 publications

References 26 publications

Evaluation and Treatment of Neurogenic Bowel Dysfunction – A Review

Evaluation and Treatment of Neurogenic Bowel Dysfunction – A Review

Multiple Sclerosis and Risk of Infection-Related Hospitalization and Death in US Veterans

Overactive bladder symptoms in patients with multiple sclerosis: Frequency, severity, diagnosis and treatment

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