Prevalence of Blood-Borne Viral Infections among Blood Donors of Tripura

Abstract

Background Blood-borne viral infections, like hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV), are most common during blood transfusion. Morbidity and mortality resulting from the transfusion of infected blood have far reaching consequences not only for the recipients themselves but also for their families, communities and the wider society.Aims The study was designed to determine the prevalence of HBV, HCV and HIV among voluntary and replacement blood donors of Tripura, India, and to study the trends of HBV, HCV and HIV infections in the population.Materials and methods This study is a retrospective cross-sectional study. The data was collected for consecutive 8 years from 2005 to 2013. Analyses were done in respect of total blood collection and HBV, HCV and HIV infections among the donors.Results Among all donors, 91.8% was voluntary donors and 8.2% was replacement donors. The average HBV, HCV and HIV positivity was 1.2% (95% CI: 1.155-1.255), 0.109% (95% CI: 0.0950.125) and 0.093% (95% CI: 0.080-0.108) respectively. Among these, HBV seropositivity was 1.19% among voluntary donors and 1.33% among replacement donors and, in case of HCV and HIV, the seropositivity among voluntary and replacement donors were 0.109%, 0.11% and 0.089%, 0.145% respectively. HBV positivity was reduced in 8 years, whereas those of HCV and HIV remain unchanged.Conclusion The most important observation of this study is gradual decrease in prevalence of HBV (p = 0.0018), whereas change in prevalence of HCV and HIV was not statistically significant. This might be due to mass hepatitis B vaccination program in Tripura.How to cite this article: Bhaumik P, Debnath K. Prevalence of Blood-Borne Viral Infections among Blood Donors of Tripura. Euroasian J Hepato-Gastroenterol 2014;4(2):79-82.

Seroprevalence of Transfusion Transmissible Infections Among Blood Donors at a Tertiary Care Teaching Hospital in Ajmer, Rajasthan: A 5 Year Study

“…In the present study, out of total donors, voluntary donors constituted 71.8% and replacement donors 28.2%. Voluntary blood donation (%) in our study was higher than study done by Bhawani et al [19] (41.64%), Fernandes et al [20] (61.2%), Kaur et al [21] (45%), and lower than Bhaumik et al [1] (91.8%).…”

“…Blood transfusion is a lifesaving intervention in an accident, in case of anemia and other hematological diseases. It was discovered by James Bundell in 1818 [1]. Like all other medical interventions, it also has different adverse effects and risks.…”

Seroprevalence of Transfusion Transmitted Infections among Blood Donors Attending a Tertiary Care Hospital of Western Odisha

“…Blood transfusion is a lifesaving intervention in an accident, in case of anaemia and other haematological diseases. It was discovered by Dr James Bundell in 1818 1 . Like all other medical interventions, it also has different adverse effects and risks.…”

Screening of Blood Donors for Transfusion Transmitted Infections in Tertiary Care Hospital of Faisalabad

“…These protective measures though have dramatically reduced the risk of transfusion transmissible infections (TTIs), but it still 1, 2 remains a major concern. Blood transfusion continues to be a major source of viral, bacterial and parasitic 2,4 infections. Blood donation during window period might transmit diseases to the recipients and prevalence of these asymptomatic carriers poses a serious challenge 1 to blood safety.…”