Prevalence of blood group antigens among regular blood donors: A single center study from South India with a review of national literature

Simultaneous high throughput genotyping of 36 blood group systems using NGS based on probe capture technology

“…From the results of the NGS method, only one high-frequency genotype was found in the following blood group systems, including P1PK, Lutheran, Kell, Yt, Xg, Scianna, Colton, Kx, Cromer, Knops, Indian, Ok, Raph, John Milton Hagen, I, Gill, FORS, Rh-associated glycoprotein, FORS, Vel, CD59, and Augustine blood groups. In addition, red blood cell phenotype frequencies among Chinese in this study was compared to reported data in other populations ( Table 2 ) [ [23] , [24] , [25] , [26] ].…”

“…All polymorphism sites in the exon and flanking intron regions of 36 blood group systems can theoretically be detected by the NGS method. There are differences in phenotypes of the blood group systems in different countries and regions [ [23] , [24] , [25] , [26] ]. Interestingly, some null alleles were found.…”