Prevalence of bone and soft tissue tumors

Yuceturk, Guven; Sabah, Dündar; Keçeci, Burçin; Kara, Ahmet Duran; Yalcinkaya, Selcuk

doi:10.3944/aott.2011.2504

Cited by 29 publications

(25 citation statements)

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“…In the current study, we aimed to determine the frequencies of primary bone tumors and tumorlike lesions of bone and the anatomical sites of their occurrence in the pediatric population. Bone tumors are classified as benign or malignant according to the tissue of origin, as well as their patterns of growth and behavior [6][7][8]. The majority of pediatric bone tumors are of benign character with distinctive and specific radiographic and clinical features, obviating the need for biopsy [9].…”

Section: Resultsmentioning

confidence: 99%

Primary Tumors and Tumor-Like Lesions of Bone in Children

Mathew¹,

Jose²

2017

IJIMS

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Section: Resultsmentioning

confidence: 99%

Primary Tumors and Tumor-Like Lesions of Bone in Children

Mathew¹,

Jose²

2017

IJIMS

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“…[8][9][10][11][12][13]. We, thus, aimed to create an additional regional data resource by examining 16-year data in our department.…”

Section: Discussionmentioning

confidence: 99%

Distribution and evaluation of primary bone and soft tissue tumors admitted from Malatya province and surrounding provinces

Sevimli¹

2017

Med-Science

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In this study characteristics and distribution of primary bone and soft tissue tumors which were operated in Inonu University Turgut Ozal Medical Center Department of Orthopaedics and Traumatology between January 2000 and December 2016 and comparison with the literature is aimed. Our study is retrospective and descriptive and 710 patients [275 M, 435 F, mean age: 30,67 (1-92)] who hospitalized with pre-diagnosis of a tumor were evaluated. Patients were analyzed according to age, gender, tumor frequency and localization. Of 710 cases which were taken into evaluation as primary bone and soft tissue tumors; 391 (55%) were determined to be bone tumors and 319 (45%) were determined to be soft tissue tumors. The most commonly seen benign bone tumor was determined to be osteochondroma (86; 25,59%) and then non-ossified fibroma (54; 16%), whereas the most commonly seen malignant bone tumor was determined to be chondrosarcoma (16, 29%) and then multiple myeloma (14; 25,45%) and osteosarcoma (8;15,54%). Among soft tissue tumors, the most commonly seen benign tumor was found to be ganglion cyst (cystic hygroma) (107; 36,1%), followed by lipoma (41; 13,99%) and tendon sheath giant cell tumor (33; 11,26%), whereas the most commonly seen malignant soft tissue tumor was found to be liposarcoma (6; 23,07) and malignant mesenchymal tumor (5; 19,23%), followed by pleomorphic undifferentiated sarcoma (5; 19,23%). In our country, statistical studies concerning distribution of bone and soft tissue tumors are progressively increasing. We suggest that larger series published by collecting from different centers are of particular importance in regard to epidemiological characteristics of bone and soft tissue tumors, as well as guiding in diagnosis and treatment.

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“…Th e number of people who lose their lives annually in the world due to cancer is about 7.6 million [1]. Th is includes approximately 170,000 to 175,000 solely in Turkey [2]. It is estimated that the number of annual deaths in the world linked with cancer of the digestive system is approximately 920,000 [1].…”

Section: Introductionmentioning

confidence: 99%

“…It is estimated that the number of annual deaths in the world linked with cancer of the digestive system is approximately 920,000 [1]. In Turkey, the number of deaths due to gastric cancer is estimated to be about 64,000 [2].…”

Section: Introductionmentioning

confidence: 99%

Polymorphisms in DNA repair genes XRCC2 and XRCC3 risk of gastric cancer in Turkey

et al. 2014

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We studied the prevalence of polymorphisms in genes XRCC2 and XRCC3 in stomach cancer patients who lived in North Eastern Turkey. A total of 61 cancer patients and 78 controls were included in this study. Single nucleotide changes were studied in XRCC2 and XRCC3 genes at locus Arg188His and Th r241Met. Blood samples were taken from the patients and controls, and DNA was isolated. Th e regions of interest were amplifi ed using a polymerase chain reaction method. After amplifi cation, we used restriction enzymes (HphI and NcoI) to digest the amplifi ed product. Digested product was then run through gel electrophoresis. We identifi ed changes in the nucleotides in these specifi c regions. It was found that the Arg188His polymorphism of the XRCC2 gene was about 39 (24 out of the 61) among cancer patients. However, only 15 (12 out of 78) of the control group indicated this polymorphism. We also observed that 18 of the 61 cancer patients (29) carried the Th r241Met polymorphism of the XRCC3 gene whereas 11 of the 78 (14) individuals in the control group had the polymorphism. Our results showed a signifi cant diff erence in polymorphism ratios between the cancer patients and health control group for the regions of interest. Th is result clearly showed that these polymorphisms increase the risk of stomach cancer and might be a strong marker for early diagnosis of gastric cancer.

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Prevalence of bone and soft tissue tumors

Abstract: Turkey still lacks a comprehensive series indicating the incidence and diagnostic distribution of bone and soft tissue tumors. The presented data would add to our knowledge on the specific rates of the bone and soft tissue tumors in Aegean region.

Cited by 29 publications

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Primary Tumors and Tumor-Like Lesions of Bone in Children

Primary Tumors and Tumor-Like Lesions of Bone in Children

Distribution and evaluation of primary bone and soft tissue tumors admitted from Malatya province and surrounding provinces

Polymorphisms in DNA repair genes XRCC2 and XRCC3 risk of gastric cancer in Turkey

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