Prevalence of bovine leukemia in 1983–2019 in China: A systematic review and meta-analysis

Ma, Baoyi; Gong, Qing‐Long; Sheng, Chen-Yan; Liu, Yi; Ge, Gui-Yang; Li, Dongli; Diao, Nai-Chao; Kai-quan, Shi; Li, Jianming; Sun, Zhibo; Zong, Ying; Xue, Lei; Du, Rui

doi:10.1016/j.micpath.2020.104681

Cited by 8 publications

(12 citation statements)

References 22 publications

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“…In China, a meta-analysis study was conducted to measure the prevalence of BLV during the period between 1983 and 2019. It recorded a 10% pooled BLV prevalence rate (4701 seropositive animals of 34,954 animals) [79]. BLV has also been recorded in some Middle Eastern countries [74].…”

Section: Blv Prevalencementioning

confidence: 97%

Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective

Marawan

Alouffi

Tokhy

et al. 2021

Viruses

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Bovine leukaemia virus (BLV) is a deltaretrovirus that is closely related to human T-cell leukaemia virus types 1 and 2 (HTLV-1 and -2). It causes enzootic bovine leukosis (EBL), which is the most important neoplastic disease in cattle. Most BLV-infected cattle are asymptomatic, which potentiates extremely high shedding rates of the virus in many cattle populations. Approximately 30% of them show persistent lymphocytosis that has various clinical outcomes; only a small proportion of animals (less than 5%) exhibit signs of EBL. BLV causes major economic losses in the cattle industry, especially in dairy farms. Direct costs are due to a decrease in animal productivity and in cow longevity; indirect costs are caused by restrictions that are placed on the import of animals and animal products from infected areas. Most European regions have implemented an efficient eradication programme, yet BLV prevalence remains high worldwide. Control of the disease is not feasible because there is no effective vaccine against it. Therefore, detection and early diagnosis of the disease are essential in order to diminish its spreading and the economic losses it causes. This review comprises an overview of bovine leukosis, which highlights the epidemiology of the disease, diagnostic tests that are used and effective control strategies.

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Section: Blv Prevalencementioning

confidence: 97%

Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective

Marawan

Alouffi

Tokhy

et al. 2021

Viruses

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“…The practical value of Belyaev’s concept has been realized in a huge collection of commercial fur colors—e.g., “Amber-gold pastel,” “Ashen,” “Beige,” “Black crystal,” “Cobalt,” “Ermine-like,” “Peach,” ““Pearl,” Platinum,” “Purple,” “Silver sable-like,” “Steel-blue,” and “Straw,”—rarely or never seen in the wild [ 6 ]. The concept’s fundamental importance has found confirmation in a large variety of breeds of dogs [ 7 ], cats [ 8 ], pigs [ 9 ], cows [ 10 ], horses [ 11 ], sheep [ 12 ], goats [ 13 ], chickens [ 14 ], ducks [ 15 ], geese [ 16 ], and other domestic animals [ 17 ] as well as in artificial shelters and additional feeding for wild animals in wildlife for saving them [ 18 ]. On the basis of Belyaev’s concept [ 1 ], a laboratory model of animal domestication by humans has been created using outbred lines of tame and aggressive rats artificially bred [ 19 ] for performance on a standard glove test [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Domestication Explains Two-Thirds of Differential-Gene-Expression Variance between Domestic and Wild Animals; The Remaining One-Third Reflects Intraspecific and Interspecific Variation

Chadaeva

Пономаренко

Kozhemyakina

et al. 2021

Animals

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Belyaev’s concept of destabilizing selection during domestication was a major achievement in the XX century. Its practical value has been realized in commercial colors of the domesticated fox that never occur in the wild and has been confirmed in a wide variety of pet breeds. Many human disease models involving animals allow to test drugs before human testing. Perhaps this is why investigators doing transcriptomic profiling of domestic versus wild animals have searched for breed-specific patterns. Here we sequenced hypothalamic transcriptomes of tame and aggressive rats, identified their differentially expressed genes (DEGs), and, for the first time, applied principal component analysis to compare them with all the known DEGs of domestic versus wild animals that we could find. Two principal components, PC1 and PC2, respectively explained 67% and 33% of differential-gene-expression variance (hereinafter: log2 value) between domestic and wild animals. PC1 corresponded to multiple orthologous DEGs supported by homologs; these DEGs kept the log2 value sign from species to species and from tissue to tissue (i.e., a common domestication pattern). PC2 represented stand-alone homologous DEG pairs reversing the log2 value sign from one species to another and from tissue to tissue (i.e., representing intraspecific and interspecific variation).

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“…Enzootic bovine leukosis (EBL) is a chronic lymphoproliferative disorder caused by bovine leukemia virus (BLV), of the genus Deltaretrovirus and family Retroviridae ( Benitez et al , 2019 , 2020 ; Kobayashi et al , 2020 ; Bulla-Castañeda et al , 2021 ; Cândida Ramalho et al , 2021 ; Nakada et al , 2023 ). BLV generates a chronic, progressive, and contagious disease characterized by malignant lymphoid cell hyperplasia and systemic lymphadenopathy, which affects almost all countries and regions where cattle are raised ( Ma et al , 2021 ). The disease is considered an economically important infection of dairy cattle and the common mode of virus spread is horizontal or iatrogenic transmission, through direct and indirect exposure of susceptible animals to infected lymphocytes from blood, milk, colostrum, and by natural mating ( Benitez et al , 2019 ; Kuczewski et al , 2021 ; Jiménez Sánchez et al , 2022 ).…”

Section: Introductionmentioning

confidence: 99%

“…BLV infection leads to decreased immune function, making animals more vulnerable to other diseases, which could shorten their productive life ( Benitez et al , 2020 ). On the other hand, could be a potential zoonotic disease, Ma et al (2021) and Olaya-Galan et al (2021) reported that BLV has been found in the blood and mammary tissues of women with breast cancer, and an association between this and the virus was confirmed in Colombia, as an intermediate risk factor; however, the link between BLV and human breast cancer is somewhat controversial. Moreover, there is no specific treatment for the disease or commercial vaccine that allows the prevention of the disease ( Bulla-Castañeda et al , 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Risk factors associated with enzootic bovine leukosis in Boyacá and Cundinamarca municipalities, Colombia

Buitrago,

eda,

Forero

et al. 2023

Open Vet J

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Background: Enzootic Bovine Leukosis (EBL) is a lymphoproliferative disorder caused by Bovine Leukemia Virus (BLV), a virus of the Retroviridae family. The infection is distributed worldwide, and a high percentage of animals infected by the BLV are asymptomatic and act as carriers of the virus in many cattle populations. Aim: To identify the risk factors associated with EBL in municipalities of Boyacá and Cundinamarca (Colombia). Methods: A simple descriptive cross-sectional study with random sampling was conducted. A total of 1140 blood samples were taken from cattle (females and males) from the municipalities of Chiquinquirá, Ubaté and San Miguel de Sema, of different breeds and age groups. The samples were processed using the commercial ELISA SERELISA® BLV Ab Mono Blocking kit (sensitivity 97%, specificity 98%). The data were processed with the statistical programs WinEpi and Epi Info® version 7.2.4.0, estimating the prevalence ratio, implementing Chi-square test (p≤0.05) and logistic regression. Results: A true prevalence (TP) and apparent prevalence (AP) of 23.61 and 22.7% in Ubaté, 19.22 and 18.1% in Chiquinquirá and 15.61 and 14.3% in San Miguel de Sema, respectively, were established. Bovines 2-4 years old were the most prevalent in Ubaté and Chiquinquirá (37.5% and 21.21% respectively), while in San Miguel de Sema individuals >4 years had the highest percentage of antibodies (18.3%). The Holstein breed had a higher prevalence in Ubaté and San Miguel de Sema (26.02% and 19.67%), and crossbreeds were more BLV-seroprevalence in Chiquinquirá (20.20%). In Ubaté, re-use of needles was identified as risk factors, contaminated blood in needle is considered one of the main routes of transmission. On the other hand, manual milking was identified as risk factors in San Miguel de Sema. Conclusion: The non-implementation of an individual needle per animal in Ubaté; the Holstein breed and manual milking in San Miguel de Sema were identified as risk factors for the presence of antibodies against the disease. EBL prevention and control plans should be established that focus on the implementation of management and sanitary practices based on herd biosecurity.

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Prevalence of bovine leukemia in 1983–2019 in China: A systematic review and meta-analysis

Cited by 8 publications

References 22 publications

Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective

Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective

Domestication Explains Two-Thirds of Differential-Gene-Expression Variance between Domestic and Wild Animals; The Remaining One-Third Reflects Intraspecific and Interspecific Variation

Risk factors associated with enzootic bovine leukosis in Boyacá and Cundinamarca municipalities, Colombia

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