Prevalence of cardiomyopathy in apparently healthy cats

Paige, Christopher F.; Abbott, Jonathan A.; Elvinger, François; Pyle, R. Lee

doi:10.2460/javma.234.11.1398

Cited by 219 publications

(222 citation statements)

References 20 publications

Supporting

Mentioning

195

Contrasting

Unclassified

Order By: Relevance

“…24-26,d The frequency of murmur detection appears to increase with repeated examinations 26 and with stimulation of the cat. 25 Among adult cats with incidentally detected murmurs but no overt clinical signs, the prevalence of heart disease has been reported as 16 of 103 (16%) to 44 of 57 (77%), varying by geographic location, examiners, and study methods. [24][25][26][27][28][29] The most common underlying heart disease in adult cats is hypertrophic cardiomyopathy (found in 15/103 [15%] to 38/61 [62%] of adult cats with incidentally detected murmurs), and the most common nonpathological murmur is caused by dynamic right ventricular outflow tract obstruction (8/103 [8%] to 9/57 [16%] of adult cats with incidentally detected murmurs).…”

Section: Heart Murmurs In Adult and Geriatric Catsmentioning

confidence: 99%

Management of incidentally detected heart murmurs in dogs and cats

Côté¹,

Edwards²,

Ettinger³

et al. 2015

javma

Self Cite

View full text Add to dashboard Cite

Section: Heart Murmurs In Adult and Geriatric Catsmentioning

confidence: 99%

Management of incidentally detected heart murmurs in dogs and cats

Côté¹,

Edwards²,

Ettinger³

et al. 2015

javma

Self Cite

View full text Add to dashboard Cite

“…In contrast, such a drastic symptom was not observed in cats with asymptomatic HCM. Cardiac murmur due to outflow obstruction or systolic anterior motion (SAM) of the mitral valve is not always heard in cats with asymptomatic HCM [4,16,17]. The ability of thoracic radiography to detect ventricular hypertrophy is very low [12,17].…”

mentioning

confidence: 99%

The Diagnostic Significance of the Plasma N-Terminal Pro-B-Type Natriuretic Peptide Concentration in Asymptomatic Cats with Cardiac Enlargement

Tominaga

Miyagawa

Toda

et al. 2011

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. We evaluated the diagnostic significance of the N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration in asymptomatic cats with cardiac enlargement. The plasma NT-proBNP concentration was measured in 21 clinically healthy control cats, and 67 asymptomatic cats with cardiac enlargement defined as end-diastolic interventricular septum thickness (IVSd) and/or diastolic left ventricular posterior wall thickness (LVPWd) >0.6 cm, vertebla heart scale (VHS) >7.8, and/or left atria/aorta ratio (LA/Ao) >1.5. The plasma NT-proBNP concentration in the asymptomatic cats with cardiac enlargement (median: 662.0, range: 24.0-2,449.0 pmol/l) was significantly higher than that in the controls (24.0, 24.0-95.0 pmol/l, P<0.001). The plasma NT-proBNP concentration was significantly correlated with the VHS, LA/Ao, IVSd and LVPWd (r=0.578, P<0.001; r=0.462, P<0.001; r=0.563, P<0.001; and r=0.764, P<0.001, respectively). Receiver operating characteristic analysis showed a cut-off value of 95.0 pmol/l for the detection of asymptomatic cats with cardiac enlargement, sensitivity and specificity of 88.1 and 100%, respectively, and an area under the curve of 0.971. These results suggest that the determination of the plasma NT-proBNP concentration can be a useful screening test for asymptomatic cats with cardiac enlargement.

show abstract

“…De acordo com Kittleson et al (1999), Chetboul et al (2006) e McDonald et al (2007, a CMH é a principal cardiopatia causadora de mortalidade e morbidade nos felinos. Em humanos, estima-se que a prevalên-cia seja de um a cada 500 indivíduos (Mattos et al 2013); em gatos, a prevalência descrita varia de 8,5% (Granström et al 2011) a 41,5% (Paige et al 2009), com diferenças de acordo com o padrão racial avaliado. No presente trabalho, seis gatos (7,31%), foram considerados suspeitos para a CMH.…”

Section: Discussionunclassified

Sensibilidade e especificidade do exame eletrocardiográfico na detecção de sobrecargas atriais e/ou ventriculares em gatos da raça Persa com cardiomiopatia hipertrófica

et al. 2016

View full text Add to dashboard Cite

ABSTRACT.-Pellegrino A., Daniel A.G.T., Pessoa R., Guerra J.M., Lucca G. Hypertrophic cardiomyopathy (HCM) is the most common feline heart disease and is characterized by increased cardiac mass with a hypertrophied and not dilated left ventricle. The echocardiography is the best noninvasive diagnostic tool for the differentiation of cardiomyopathies and is considered the gold standard for detection of ventricular hypertrophy present in HCM. Electrocardiographic changes are also common in animals with HCM and the electrocardiogram (ECG) is quick, easy and highly available screening test for the detection of ventricular hypertrophy in humans. In cats, few studies have been conducted regarding the sensitivity and specificity of ECG in detecting ventricular hypertrophy. With the intention of evaluating the use of ECG as a screening tool for diagnosis of HCM in cats, Persian cats (n=82) were evaluated by echocardiographic and electrocardiographic examinations. Animals with blocks and/or conduction disturbances were excluded from statistical analysis (n=22). Subsequently the animals included were classified as normal (n=38), suspicious (n=6) and affected by HCM (n=16). Statistical differences were observed in the P-wave amplitude in DII and R-wave amplitude in DII, CV6LL and CV6LU, with higher values in animals with HCM. Velocities and pressure gradient of aortic flow, left atrial diameter (LA) and LA/Ao ratio were higher in cats with HCM. Among the animals with ECG changes suggestive of left atrial enlargement (n=7), only two actually had LA enlargement on echocardiography, and among animals with left atrial enlargement on echocardiogram (n=7), only two had ECG changes suggestive of overload AE (40,4% of sensibility and 90,9% of specificity). Among the animals with ECG changes suggestive of left ventricular hypertrophy (n=6), five actually had ventricular hypertrophy on echocardiography, and among animals with HCM by echocardiography (n=16), only five showed electrocardiographic abnormalities suggestive of LV hypertrophy (31,25% of sensibility and 97,72% of 1 Recebido em 6 de abril de 2015.Aceito para publicação em 2 de fevereiro de 2016.

show abstract

Prevalence of cardiomyopathy in apparently healthy cats

Abstract: Cardiomyopathy was common in the healthy cats evaluated in this study. In apparently healthy cats, detection of a heart murmur is not a reliable indicator of cardiomyopathy.

Cited by 219 publications

References 20 publications

Management of incidentally detected heart murmurs in dogs and cats

Management of incidentally detected heart murmurs in dogs and cats

The Diagnostic Significance of the Plasma N-Terminal Pro-B-Type Natriuretic Peptide Concentration in Asymptomatic Cats with Cardiac Enlargement

Sensibilidade e especificidade do exame eletrocardiográfico na detecção de sobrecargas atriais e/ou ventriculares em gatos da raça Persa com cardiomiopatia hipertrófica

Contact Info

Product

Resources

About