Prevalence of cardiovascular risk factors in an urban adult population from southern Spain. IMAP Study

Gómez-Huelgas, Ricardo; Mancera-Romero, José; Bernal-López, María Rosa; Jansen-Chaparro, Sergio; Baca-Osorio, A.; Toledo, Estefanía; Pérez‐González, Rocío; Guijarro-Merino, Ricardo; Tinahones, Francisco J.

doi:10.1111/j.1742-1241.2010.02543.x

Cited by 16 publications

(11 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar associations were observed with fasting glucose levels, but HbA1c strongly correlates with the level of ambient glycemia during a 2 to 3 month period, so that it reflects the usual daily fasting and postprandial glucose levels as established by the American Diabetes Association (ADA) [19]. Since a high prevalence of cardiovascular risk factors has been recently reported in this particular population [15,16], these findings may be crucial for implementing prophylactic interventions in order to prevent or delay CKD and CVD.…”

Section: Discussionsupporting

confidence: 58%

“…The methodology of the IMAP study has been reported previously [16,17]. The participants were located and invited by telephone to participate in the study.…”

Section: Methodsmentioning

confidence: 99%

“…A higher prevalence of cardiovascular risk factors, especially dyslipidemia and obesity, has been reported in southern Spain [15,16]. …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association of HbA1c and cardiovascular and renal disease in an adult Mediterranean population

et al. 2013

View full text Add to dashboard Cite

BackgroundIncreasing evidence suggests a mechanistic link between the glycemic environment and renal and cardiovascular events, even below the threshold for diabetes. We aimed to assess the association between HbA1c and chronic kidney disease (CKD) and cardiovascular disease (CVD).MethodsA cross-sectional study involving a random representative sample of 2270 adults from southern Spain (Malaga) was undertaken. We measured HbA1c, serum creatinine and albuminuria in fasting blood and urine samples.ResultsIndividuals without diabetes in the upper HbA1c tertile had an unfavorable cardiovascular and renal profile and shared certain clinical characteristics with the patients with diabetes. Overall, a higher HbA1c concentration was strongly associated with CKD or CVD after adjustment for traditional risk factors. The patients with known diabetes had a 2-fold higher odds of CKD or CVD. However, when both parameters were introduced in the same model, the HbA1c concentration was only significantly associated with clinical endpoints (OR: 1.4, 95% CI, 1.1-1.6, P = 0.002). An increase in HbA1c of one percentage point was associated with a 30% to 40% increase in the rate of CKD or CVD. This relationship was apparent in persons with and without known diabetes. ROC curves illustrated that a HbA1c of 37 mmol/mol (5.5%) was the optimal value in terms of sensitivity and specificity for predicting endpoints in this population.ConclusionHbA1c levels were associated with a higher prevalence of CKD and CVD cross-sectionally, regardless of diabetes status. These data support the value of HbA1c as a marker of cardiovascular and renal disease in the general population.

show abstract

Section: Discussionsupporting

confidence: 58%

“…The methodology of the IMAP study has been reported previously [16,17]. The participants were located and invited by telephone to participate in the study.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Association of HbA1c and cardiovascular and renal disease in an adult Mediterranean population

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The prevalence of general and abdominal obesity has been recently studied in a national sample of Spanish general (>18 years) and elderly (≥65 years) population [11,12] and in regional samples [13-18]. However, the association of both types of obesity with the 10-year coronary disease risk estimated with the Framingham-REGICOR risk functions validated for the Spanish population [19] has not been studied in depth.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of obesity and associated cardiovascular risk: the DARIOS study

Félix-Redondo¹,

Grau

Baena-Díez

et al. 2013

BMC Public Health

View full text Add to dashboard Cite

BackgroundTo estimate the prevalence of overweight and obesity in the Spanish population as measured with body mass index (BMI), waist circumference (WC) and waist to height ratio (WHtR) and to determine the associated cardiovascular risk factors.MethodsPooled analysis with individual data from 11 studies conducted in the first decade of the 21st century. Participants aged 35–74 years were asked about the history of cardiovascular diseases, hypertension, diabetes and hypercholesterolemia. Height, weight, WC, blood pressure, glycaemia, total cholesterol, low-density and high-density lipoprotein cholesterol and coronary risk were measured. The prevalence of overweight (BMI 25–29.9 kg/m2), general obesity (BMI ≥30 kg/m2), suboptimal WC (≥ 80 cm and < 88 in women, ≥ 94 and < 102 in men), abdominal obesity (WC ≥88 cm ≥102 cm in women and men, respectively) and WHtR ≥0.5 was estimated, standardized for the European population.ResultsWe included 28,743 individuals. The prevalence of overweight and suboptimal WC was 51% and 30% in men and 36% and 22% in women, respectively; general obesity was 28% in both sexes and abdominal obesity 36% in men and 55% in women. The prevalence of WHtR ≥0.5 was 89% and 77% in men and women, respectively. All cardiovascular risk factors were significantly associated with abnormal increased values of BMI, WC and WHtR. Hypertension showed the strongest association with overweight [OR = 1.99 (95% confidence interval 1.81-2.21) and OR = 2.10 (1.91-2.31)]; suboptimal WC [OR = 1.78 (1.60-1.97) and OR = 1.45 (1.26-1.66)], with general obesity [OR = 4.50 (4.02-5.04), and OR = 5.20 (4.70-5.75)] and with WHtR ≥0.5 [OR = 2.94 (2.52-3.43), and OR = 3.02 (2.66-3.42)] in men and women respectively, besides abdominal obesity in men only [OR = 3.51 (3.18-3.88)]. Diabetes showed the strongest association with abdominal obesity in women [OR = 3,86 (3,09-4,89).ConclusionsThe prevalence of obesity in Spain was high. Overweight, suboptimal WC, general, abdominal obesity and WHtR ≥0.5 was significantly associated with diabetes, hypertension, hypercholesterolemia and coronary risk. The use of lower cut-off points for both BMI and particularly WC and could help to better identify the population at risk and therefore achieve more effective preventive measures.

show abstract

“…Yet it is commonly thought that these are mostly applicable only to the miserable Northern world whilst in the Mediterranean the sun shines, families frolic happily in the street (to the songs of Zorba/Radio Tarifa or nowadays Abba) and the local diet obviates the need for any further measures. The paper by Gomez‐Huelgas in this issue gives the lie to this rosy‐tinted scenario (2). The reality of life in a survey of 2270 participants is an obesity prevalence of 60%, sedentary lifestyles in 77%, 65% with dyslipidaemia, 27% smoking, 33% with hypertension and 15% with dysglycaemia and 7% with diabetes.…”

mentioning

confidence: 99%

Cardiovascular screening: which populations, what measures of risk?

Wierzbicki

2010

International Journal of Clinical Practice

View full text Add to dashboard Cite

Prevalence of cardiovascular risk factors in an urban adult population from southern Spain. IMAP Study

Cited by 16 publications

References 25 publications

Association of HbA1c and cardiovascular and renal disease in an adult Mediterranean population

Association of HbA1c and cardiovascular and renal disease in an adult Mediterranean population

Prevalence of obesity and associated cardiovascular risk: the DARIOS study

Cardiovascular screening: which populations, what measures of risk?

Contact Info

Product

Resources

About