Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index

Redondo, María J.; Foster, Nicole C.; Libman, Ingrid; Mehta, Sanjeev N.; Hathway, J.; Bethin, Kathleen E.; Nathan, Brandon M.; Ecker, Michelle A.; Shah, Avni; DuBose, Stephanie N.; Tamborlane, William V.; Hoffman, Robert R.; Wong, Jenise C.; Maahs, David M.; Beck, Roy W.; DiMeglio, Linda A.

doi:10.1007/s00592-015-0785-1

Cited by 65 publications

(66 citation statements)

References 34 publications

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“…The T1D Exchange recently documented that 36% of adolescents with T1D are overweight/obese [20, 21••], which is consistent with the SEARCH for Diabetes in Youth Study [22] and other US T1D samples [23, 24] but higher than the general population [25]. In addition, Canadian and Polish studies of children and adolescents with T1D found that 35 and 30%, respectively, were overweight/obese [26, 27].…”

Section: Weight Status In Type 1 Diabetessupporting

confidence: 58%

Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps

et al. 2017

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Purpose of Review This review aims to summarize the type 1 diabetes (T1D) and weight literature with an emphasis on barriers associated with weight management, the unique T1D-specific factors that impact weight loss success, maladaptive and adaptive strategies for weight loss, and interventions to promote weight loss. Recent Findings Weight gain is associated with intensive insulin therapy. Overweight and obese weight status in individuals with T1D is higher than the general population and prevalence is rising. A variety of demographic (e.g., female sex), clinical (e.g., greater insulin needs), environmental (e.g., skipping meals), and psychosocial (e.g., depression, stress) factors are associated with overweight/obese weight status in T1D. Fear of hypoglycemia is a significant barrier to engagement in physical activity. Studies evaluating adaptive weight loss strategies in people with T1D are limited. Summary There is a growing literature highlighting the prevalence and seriousness of overweight and obesity among both youth and adults with T1D. There is an urgent need to develop evidence-based weight management guidelines and interventions that address the unique concerns of individuals with T1D and that concurrently address glycemic control.

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Section: Weight Status In Type 1 Diabetessupporting

confidence: 58%

Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps

et al. 2017

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“…Redondo et al found a dyslipidemia prevalence of 3.8% in the US with 11,348 T1D patients aged 2-18 years. The authors attributed this low ratio of dyslipidemia to the facts that the patients included in the study were mostly younger and highly active children and that the number of obese subjects was low [18]. In a study from Brazil, the ratio of dyslipidemia among 239 patients with T1DM was 72.5% and it was shown that dyslipidemia developed most frequently due to hypercholesterolemia and less frequently due to hyperglyceridemia.…”

Section: Discussionmentioning

confidence: 99%

“…Dyslipidemia frequency in diabetic children varies between 3.8% and 72.5% in different studies [14][15][16][17][18][19], and hypercholesterolemia was reported as the most frequent finding [16,[19][20][21]. Redondo et al found a dyslipidemia prevalence of 3.8% in the US with 11,348 T1D patients aged 2-18 years.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of dyslipidemia and associated factors in children and adolescents with type 1 diabetes

Bulut

Demirel

Metìn

2017

Journal of Pediatric Endocrinology and Metabolism

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Background: Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents. Methods: The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files. Results: Dyslipidemia prevalence was found to be 26.2%. Hypercholesterolemia (15.8%) and hyperglyceridemia (12.9%) were most common findings. Age, body mass index (BMI), hemoglobin A 1c (A 1C ) and poor metabolic control were significantly higher in cases with dyslipidemia. Smoking rate was 14.1% in the pubertal group. Poor metabolic control and dyslipidemia was found higher among smokers (p < 0.05).Conclusions: Blood lipid levels should be monitored regularly and nutrition education should be repeated periodically to prevent and control dyslipidemia in patients with T1D. Smoking-related risks should be a part of patient education in the pubertal period.

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“…The relationship between cardiac autonomic dysfunction and diabetes complications appears to begin early, as observed in adolescents with type 1 diabetes with subclinical markers of cardiovascular and renal disease . Overweight and obese in adolescents with type 1 diabetes not only have higher prevalence of cardiovascular risk factors of hypertension and dyslipidemia but also have a higher risk of albuminuria . Similarly, excess weight gain in adults with type 1 diabetes is associated with complications outcomes such as retinopathy, neuropathy, and more extensive atherosclerosis .…”

Section: Discussionmentioning

confidence: 99%

Higher body mass index predicts cardiac autonomic dysfunction: A longitudinal study in adolescent type 1 diabetes

et al. 2018

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Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index

Abstract: Obese children with type 1 diabetes have a higher prevalence of hypertension and dyslipidemia than healthy weight children with type 1 diabetes. The possible association of obesity with lower micro-/macroalbuminuria rates warrants further investigation.

Cited by 65 publications

References 34 publications

Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps

Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps

The prevalence of dyslipidemia and associated factors in children and adolescents with type 1 diabetes

Higher body mass index predicts cardiac autonomic dysfunction: A longitudinal study in adolescent type 1 diabetes

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