Introduction. The aim of this study was to determine the prevalence of dental caries and analyze the status of teeth in relation to sociodemographic factors and habits and behavior related to oral health among adolescents in the eastern region of Republika Srpska. Material and Methods. The study included 212 adolescents (71 males and 141 females) age 16-18 years. Information about sociodemographic characteristics, oral hygiene habits and behaviors related to oral health were collected using a questionnaire. The prevalence of dental caries was determined by applying the DMFT index and its components (D - decayed, M - extracted, F - filled teeth). The status of teeth was analyzed in relation to socio-demographic variables, oral hygiene habits and behavior related to oral health. Results. The mean DMFT value of examined population was approximately 8.6. A significant difference in the status of teeth of adolescents was reported in relation to the place of residence and oral hygiene habits - brushing frequency and the use of dental floss. A significant difference in the caries prevalence was recorded depending on the elapsed time from last visit and reasons for visiting dentist. Conclusion. The results suggested that the place of residence, oral hygiene habits and behavior related to oral health influenced the status of teeth of adolescents in the eastern region of Republika Srpska