Prevalence of cholelithiasis among persons undergoing abdominal ultrasound at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Abstract

Background: The prevalence of gallstones among Ghanaians is unknown. We aimed to determine the prevalence of gallstones among persons undergoing abdominal ultrasound at the Komfo Anokye Teaching Hospital (KATH). Methods: We performed a cross-sectional study of patients aged ≥14years presenting to KATH for abdominal ultrasound between 2009 and 2012. Patient demographics were recorded. The gallbladder was assessed by ultrasonography. Cholelithiasis was defined as presence of gallstones or absence of gallbladder. Data was expressed as descriptive and inferential statistics. Results: There were 2824 participants. 55% were females. Mean age was 47±18 years. Mean body mass index (BMI) was 24.0±5.5. Mean parity among females was 3±3. Prevalence of cholelithiasis was 5.9 (95%C.I:5.0,6.8). Females had a high prevalence compared to males (6.8 vs 4.7). Prevalence increased steadily by age. Prevalence was 6.6, 5.1 and 8.8 for patients with BMI <18.5, 18.5-24.9 and ≥30 respectively. Prevalence among women with parity of 0,1-5 and >5 was 3.1, 6.7 and 6.4 respectively.On multivariate regression analysis, female sex (AOR=1.55;p<0.05), age≥40 years (AOR=2.05;p<0.01), BMI<18.5 (AOR=1.25;p>0.05) or BMI≥30 (AOR=1.39;p>0.05) and family history of gallstones (AOR=11.9;p<0.01) increased the odds of cholelithiasis. Conclusions: Prevalence of cholelithiasis among patients undergoing ultrasonography at KATH was 5.9. Patient age, sex and family history significantly influenced the prevalence.

Cholelithiasis: causative factors, clinical manifestations and management

“…6 (Trichy) with mean age in the study of 43.56±13.18 years and other studies in literature like Shukrya Kamil Khalaf (Iraq) and Adam Gyedu (Ghana). 9,10 Maximum patients were observed in 4 th and 5 th decade in present study, which is suggestive of early occurrence of gallstone disease in Indian population that is consistent with study done by Bhatti in Lahore Pakistan and Muthalaisamy in Trichy but Veerbhadrappa in Madhya Pradesh found an increased incidence in 5 th and 6 th decade in India. [5][6][7] The decade of peak incidence in the present study is same for both genders but Selvi et al found the decade for peak incidence of cholelithiasis in females was 5 th decade and 6 th decade for males.…”

Trend over time for cholecystectomy following the introduction of laparoscopy in a Nigerian tertiary hospital

“…In spite of the phenomenal increase we found, the absolute number of cholecystectomies performed is still very low compared to many centers in Western countries. This is due to the relatively low incidence of gallstone disease in Nigeria and other West African countries which has been reported to range between 3%–6% in hospital-based studies[ 13 14 22 23 ] compared to 64%–73%/among American Indians and 14% among Black Americans in major population-based studies. [ 24 ] Being a public hospital, a number of months in different years within the period of this study were lost to incessant industrial actions of health workers across the country.…”

Hubungan Peningkatan Indeks Massa Tubuh dengan Kejadian Kolelitiasis di Bagian Bedah Digestif RSI Siti Rahmah Padang Periode Januari-Juni 2018

“…12 Hasil yang sama ditemukan pada hasil penelitian Gyedu tahun 2015, bahwa usia ≥40 tahun sebesar 1737 (61,5%). 13 Temuan lain yang sesuai adalah penelitian Dani tahun 2012 di RS Immanuel Bandung kasus kolelitiasis tertinggi usia 40-49 tahun (33,33%). 5 Hal ini sesuai dengan teori dimana usia 40 tahun keatas memiliki risiko tinggi terjadinya kolelitiasis karena pertambahan usia berkaitan dengan hipersekresi kolesterol, penurunan jumlah asam empedu, dan penurunan sekresi garam empedu.…”