Prevalence of congenital abnormalities on routine ultrasound scan of second and third trimester pregnancy

Mahela, Sangita; Talukdar, Bharat

doi:10.18203/2320-1770.ijrcog20151621

Cited by 7 publications

(8 citation statements)

References 2 publications

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“…The incidence of congenital malformation varies widely from country to country [2] and from region to region, with a range of 1.73 to 6.3% [12][13][14]. For example, it was reported to be 1.7% in Brazil [15], 2.22% in Eastern India [16], 3.63% in Iraq [17], 6.3% in Nigeria 6.3% [14].…”

mentioning

confidence: 99%

Modifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study

Mekonnen

Hordofa

Kitila

et al. 2020

BMC Pregnancy Childbirth

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Background: Congenital malformations are structural, functional, and metabolic defects that develop during the organogenesis period and present at birth or later in life. There has been little research on congenital malformations in Ethiopia, knowledge on the incidence of birth defects at birth is unknown and the etiologies of the anomalies are limited. This study, therefore, aimed to assess the modifiable risks of congenital anomalies among women in Bale zone hospitals, Ethiopia. Methods: An unmatched case-control study was conducted from February 2018 to January 2019 in the Bale zone; namely Goba referral hospital, Robe, Ginnir and Dolomena hospitals. A total of 409 women were selected. Mothers who gave birth with any type of congenital malformation were assigned as cases and those who gave live births without any congenital abnormalities were assigned as controls. Controls were selected by the lottery method from the labor ward. For each case, two consecutive controls were included. Data were entered into Epi-data 3.1 and exported into Statistical Package for the Social Sciences (SPSS) version 21 for analysis. Logistic regression was conducted to analyze the data. Results: Alarmingly, women who had been exposed to pesticides during the current pregnancy were two times more prone to give congenital malformed infants than their counterparts (AOR = 3.19; 95% CI = 1.31, 10.96). Additionally, those women who chewed khat during the periconceptional period were two times more likely to have congenital malformed infants as compared to women who did not engage in this activity (AOR = 2.40; 95% CI = 1.11, 5.19). Conclusions: Urgent attention needs to be given by public health professionals and services to khat chewing and maternal exposure to pesticides during pregnancy to reduce the risk of congenital malformations.

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confidence: 99%

Modifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study

Mekonnen

Hordofa

Kitila

et al. 2020

BMC Pregnancy Childbirth

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“…The authors in that study evaluated which the prevalence of congenital anomalies during only one year among live born neonates. They concluded that the congenital anomalies among live born neonates were 63 cases among 2517 (2.5%) [17]. The incidence of congenital malformations ranged from 1.2% to 7% as reported by many authors.…”

Section: Discussionmentioning

confidence: 87%

Predominance of fetal malformations among pregnant women: A multi-centric observational study

Sayed¹,

Khalifa²,

Shehata³

et al. 2021

Clin J Obstet Gynecol

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Objective: To observe the predominance of fetal anomalies in pregnant women in a multi-centric setting. Methods: This prospective observational study included 20225 pregnant women who came for antenatal care in University Hospital and fetal medicine units from 2016 to 2019. Fetal anatomical scanning was done for all participants. Results: One hundred eighty-three cases had fetal congenital anomalies, yielding a prevalence of around 0.9%. Third of cases had positive consanguinity, this increased in cases of skeletal and thoracic anomalies. The presence of past history of anomalies was evident in 8.2% mostly with skeletal and heart anomalies. History of drug intake was only verified in 1.6% of cases. Sixty-three women out of 183 (34.4%) were diagnosed to have anomalies in fetal nervous system. Conclusion: Prenatal diagnosis are recommended for early detection of congenital anomalies and counselling.

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“…Pradhan Mantri Surakshit Matritva Abhiyan (PMSMA), launched in 2016, supports pregnant mothers during the 2nd and 3rd trimester of pregnancy by detecting high-risk pregnancies and providing special antenatal services at government hospitals. Under this initiative, technologies such as ultrasound have been efficiently used in the gestational period to detect structural anomalies that can provide the family and relatives with more information and choices [ 23 ]. Families with previous history of an RD may be categorized under high-risk pregnancies.…”

Section: Introductionmentioning

confidence: 99%

“…Families with previous history of an RD may be categorized under high-risk pregnancies. This provides an opportunity to the family to avail timely multidisciplinary maternal–fetal intervention and an option to terminate the pregnancy in extreme cases [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Integrating rare disease management in public health programs in India: exploring the potential of National Health Mission

Choudhury

Chaube

2022

Orphanet J Rare Dis

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Rare diseases (RD) are conditions that affect a small number of people and hence do not get the focus on government health priorities in a resource-constrained setting such as India. Therefore, it is essential to focus on strengthening and utilizing the existing public health framework for the optimal usage of healthcare resources. In this regard, National Health Mission (NHM) is one of the crucial programs initiated by the government of India to address the health needs of the under-served. As Phase 1 of the NHM moves towards completion, we explored the Reproductive, Maternal, Newborn, Child, and Adolescent Health (RMNCH + A) program under NHM to assess their potential and limitations to aid RD care. We found that some of the disease-prevention initiatives of NHM address certain RDs and can easily be expanded to manage many such preventable RDs. In addition, NHM programs can provide a unique epidemiological data repository to strengthen the National Rare Disease Registry. These programs can also play important role in providing a continuum of care for many RDs that need lifelong management. However, existing programs have a limited scope to provide specialized RD-related treatments, which is better served in a more focused system. Thus, considering RDs in the design of the existing programs may help RD management better through prevention, data collection, and providing a continuum of care.

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Prevalence of congenital abnormalities on routine ultrasound scan of second and third trimester pregnancy

Cited by 7 publications

References 2 publications

Modifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study

Modifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study

Predominance of fetal malformations among pregnant women: A multi-centric observational study

Integrating rare disease management in public health programs in India: exploring the potential of National Health Mission

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