Prevalence of Dental Implants and Evaluation of Peri-implant Bone Levels in Patients Presenting to a Dental School: A Radiographic Cross-Sectional 2-Year Study

Alkan, Eylem Ayhan; Mau, Lian Ping; Schoolfield, John; Guest, Gary F.; Cochran, David L.

doi:10.11607/jomi.5756

Cited by 5 publications

(5 citation statements)

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“…In addition, in the USA, Elani et al found that 5.7% (95% CI = 4.1% to 7.7%) of patients had at least one dental implant from 2015 to 2016 among all of those with at least one missing tooth. 17 In addition, Alkan et al study and the present study were consistent and found that patients treated with single-tooth implants were the majority of all implant patients. 17 The highest risk for implant failure was associated with periodontitis followed by tobacco smoking.…”

Section: Discussionsupporting

confidence: 87%

“…17 In addition, Alkan et al study and the present study were consistent and found that patients treated with single-tooth implants were the majority of all implant patients. 17 The highest risk for implant failure was associated with periodontitis followed by tobacco smoking. 25 It has been proven in literature that tobacco smoking is a risk factor in periodontitis and that it affects healing.…”

Section: Discussionsupporting

confidence: 87%

“…15 There is a general impression that use of dental implants has been increasing, and market research indicates that the overall number of implants used has been increasing. 2,16 However, little is known about the prevalence of dental implants among different populations 2,17 including Saudi Arabia. Therefore, it's important to keep searching in order to find out the common global phenomena and in order to help implement effective health policies.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of Dental Implants in a Saudi Population

Al-Safadi

et al. 2019

ijetst

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Aim: The primary aim of this study was to detect the prevalence of dental implants in a Saudi population in the Kingdom of Saudi Arabia. The secondary objective was to describe the status of the health insurance covering dental implants in Saudi Arabia. Materials and Methods: 1831 Saudi patients aged ≥18 years with at least one missing permanent tooth and residing in the Kingdom of Saudi Arabia were randomly selected and clinically examined for implant prostheses types (single-tooth implant, implant-supported long or short span conventional fixed bridge, implant over denture). Radiographs were used too. The health insurance covering dental implants was detected. The data obtained including age, gender, systemic disease, and tobacco smoking were documented in a patient examination form then statistically analyzed using Chi-Square Test or Fisher-Freeman-Halton Test and U-Test. Results: The prevalence of dental implants among adults missing at least one tooth was 12.7%. Of those 12.7%, the majority of patients had 2-4 implants (5.4%). The majority of patients who had one implant were in the age group <40 years; patients who had >8 implants were seen in the age group ≥60. In addition, the prevalence of implant prostheses types was as the following: Single-tooth implant 75.5%, followed by implant-supported short span fixed bridge 17.1%, implant over denture 3.9%, and implant-supported long span fixed bridge 3.5%. The majority of patients treated with single-tooth implant were in the age group <40 years. There was an insignificant difference in the median number of dental implants between males and females p>0.05. Conclusion: The majority of patients were treated with single-tooth implant. Health insurance policy doesn’t cover the cost of dental implants in Saudi Arabia. Keywords: Implant, Prevalence, Prostheses/Prosthesis, Type, Patient

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Section: Discussionsupporting

confidence: 87%

Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

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Prevalence of Dental Implants in a Saudi Population

Al-Safadi

et al. 2019

ijetst

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“…Little is known about the prevalence of dental implant use among the US population (Alkan et al 2018). There is a general impression that use of implants has been increasing, and market research indicates that the overall number of implants used has been increasing.…”

Section: Introductionmentioning

confidence: 99%

Trends in Dental Implant Use in the U.S., 1999–2016, and Projections to 2026

et al. 2018

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Dental implants have become an increasingly popular treatment choice for replacing missing teeth. Yet, little is known about the prevalence and sociodemographic distribution of dental implant use in the United States. To address this knowledge gap, we analyzed data from 7 National Health and Nutrition Examination Surveys from 1999 to 2016. We estimated dental implant prevalence among adults missing any teeth for each survey period overall as stratified by sociodemographic characteristics. We calculated absolute and relative differences from 1999-2000 to 2015-2016 and fit logistic regression models to estimate changes over time. We also used multivariable logistic regression to estimate independent associations of sociodemographic covariates with the presence of any implant. We projected the proportion of patients treated with dental implants into the year 2026 under varying assumptions of how the temporal trend would continue. There has been a large increase in the prevalence of dental implants, from 0.7% in 1999 to 2000 to 5.7% in 2015 to 2016. The largest absolute increase in prevalence (12.9%) was among individuals 65 to 74 y old, whereas the largest relative increase was ~1,000% among those 55 to 64 y old. There was an average covariate-adjusted increase in dental implant prevalence of 14% per year (95% CI, 11% to 18%). Having private insurance (vs. none or public insurance) or more than a high school education (vs. high school or less) was each associated with a 2-fold increase in prevalence, with an almost 13-fold (95% CI, 8 to21) increase for older adults. Dental implant prevalence projected to 2026 ranged from 5.7% in the most conservative scenario to 23% in the least. This study demonstrates that dental implant prevalence among US adults with missing teeth has substantially increased since 1999. Yet access overall is still very low, and prevalence was consistently higher among more advantaged groups.

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“…Implant supported dentures have become a mainstream treatment in repairing dentition defects and deletions (Alkan et al, 2018; Greenberg, 2017). However, anodontia caused by serious decay, periodontal disease, congenital anodontia, and trauma may result in severe alveolar bone resorption, which can be a disadvantage of implantation.…”

Section: Introductionmentioning

confidence: 99%

Effect of GARP on osteogenic differentiation of bone marrow mesenchymal stem cells via the regulation of TGFβ1 in vitro

Sun

Yang

et al. 2019

PeerJ

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Mesenchymal stem cells (MSCs), which have multipotential differentiation and self-renewal potential, are possible cells for tissue engineering. Transforming growth factor β1 (TGFβ1) can be produced by MSCs in an inactive form, and the activation of TGFβ1 functions as an important regulator of osteogenic differentiation in MSCs. Recently, studies showed that Glycoprotein A repetitions predominant (GARP) participated in the activation of latent TGFβ1, but the interaction between GARP and TGFβ1 is still undefined. In our study, we successfully isolated the MSCs from bone marrow of rats, and showed that GARP was detected in bone mesenchymal stem cells (BMSCs). During the osteogenic differentiation of BMSCs, GARP expression was increased over time. To elucidate the interaction between GARP and TGFβ1, we downregulated GARP expression in BMSCs to examine the level of active TGFβ1. We then verified that the downregulation of GARP decreased the secretion of active TGFβ1. Furthermore, osteogenic differentiation experiments, alkaline phosphatase (ALP) activity analyses and Alizarin Red S staining experiments were performed to evaluate the osteogenic capacity. After the downregulation of GARP, ALP activity and Alizarin Red S staining significantly declined and the osteogenic indicators, ALP, Runx2, and OPN, also decreased, both at the mRNA and protein levels. These results demonstrated that downregulated GARP expression resulted in the reduction of TGFβ1 and the attenuation of osteoblast differentiation of BMSCs in vitro.

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Prevalence of Dental Implants and Evaluation of Peri-implant Bone Levels in Patients Presenting to a Dental School: A Radiographic Cross-Sectional 2-Year Study

Cited by 5 publications

References 0 publications

Prevalence of Dental Implants in a Saudi Population

Prevalence of Dental Implants in a Saudi Population

Trends in Dental Implant Use in the U.S., 1999–2016, and Projections to 2026

Effect of GARP on osteogenic differentiation of bone marrow mesenchymal stem cells via the regulation of TGFβ1 in vitro

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