Prevalence of diabetic retinopathy in Tehran province: a population-based study

Javadi, Mohammad Ali; Katibeh, Marzieh; Rafati, Nasrin; Dehghan, Mohammad Hossein; Zayeri, Farid; Yaseri, Mehdi; Sehat, Mojtaba; Ahmadieh, Hamid

doi:10.1186/1471-2415-9-12

Cited by 93 publications

(90 citation statements)

References 36 publications

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“…Prevalence of CSME increased with increasing age of diabetics. Similar observations were evident in studies which were done in the past [16][17][18]. Associated hypertension is a known risk factor for development of diabetic retinopathy [19].…”

Section: Resultssupporting

confidence: 85%

Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital – based Cross – Sectional Study

Ramavat¹

2013

JCDR

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Context: Diabetic Retinopathy (DR) can be defined as a damage which is caused to microvasculature in the retina by prolonged hyperglycaemia. Various studies have been conducted in south India, to find out prevalence of DR. It remains a less explored domain among type 2 diabetic patients in western India.Objectives: (1) To assess prevalence of diabetic retinopathy in type 2 DM in western Indian population. and (2) To find out effect of duration of diabetes on severity of DR in this population.Study Design: A hospital -based, cross -sectional study. Material and Methods:A total of 168 patients with type 2 DM underwent detailed opthalmoscopic examinations for DR. The ETDRS classification was followed to categorize retinopathy in different stages. Results:We observed that overall, prevalence of DR in type 2 patients of western India was 33.9%. Prevalences of nonproliferative DR and proliferative DR were 25.5% and 8.33% respectively. Statistically significant differences (p value<0.05) were observed between prevalences of DR in each group of patients which was classified, and duration of diabetes. Prevalence of CSME (clinically significant macular oedema) was 6.5%. Associated hypertension showed a statistically significant (p value<0.05%), higher prevalence of DR. Conclusion:This study concluded that prevalence of DR in type 2 DM patients of western India was 33.9% and that it increased with duration of diabetes. Associated hypertension is a risk factor for development of

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Section: Resultssupporting

confidence: 85%

Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital – based Cross – Sectional Study

Ramavat¹

2013

JCDR

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“…Nevertheless, our findings are supported by a growing body of evidence. Indeed, insulin use was an independent predisposing factor for DR (OR 32.71; 95% CI, 4.11-259.85) in the study by Javadi et al (15), similarly as in the SN-DREAMS III cross-sectional study (OR 3.59; 95% CI, 1.41-9.14) (16). Consistent with those findings, a large retrospective cohort study including 85,214 T2DM patients identified insulin treatment as an independent risk factor for DR (hazard ratio 2.03; 95% CI, 1.89-2.18; P<0.001) (17).…”

Section: Discussionmentioning

confidence: 82%

Association of insulin treatment versus oral hypoglycaemic agents with diabetic retinopathy and its severity in type 2 diabetes patients in Cameroon, sub-Saharan Africa

Jingi¹,

Noubiap²,

Essouma³

et al. 2016

Ann. Transl. Med.

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Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease associated with multiple macro and microvascular complications, diabetic retinopathy (DR) being the commonest one. Recent literature has reported an increased risk of DR with insulin use. Methods:We carried out a cross-sectional study at the Ophthalmology Department of the Douala General Hospital (DGH) during a 2-year period to explore the association between insulin treatment and both DR and its severity as compared with oral hypoglycemic agents (OHAs) in Cameroonian T2DM patients aged ≥35 years, and who were all screened for DR through eye examination including exhaustive retinal evaluation.Results: In total, medical files of 134 T2DM patients were analyzed. The frequency of DR was 54.1% among patients on OHA and 73.9% among those on insulin treatment, giving an overall frequency of 57.5%. There were significantly more OHA treated patients than insulin treated patients (82.8% vs. 17.2%, P<0.001). As expected, both the OHA and insulin groups were comparable by age, sex, duration of diabetes, past history of hypertension, alcohol misuse, and current tobacco smoking. DR was almost significantly more frequent in T2DM patients under insulin regimen than in patients under OHA [73.9% vs. 54.1%; odds ratio (OR) 2.4; 95% confidence interval (CI), 0.9-6.6; P=0.06]. Proliferative diabetic retinopathy (PDR) was significantly more observed in insulin treated patients than in OHA treated patients (34.8% vs. 15.3%; OR 2.95; 95% CI, 1.1-8; P=0.035). Irrespective of staging, the frequency of diabetic macular edema (DME) was significantly higher in the insulin group than in the OHA group (43.5% vs.19.8%; OR 3.1; 95% CI, 1.2-8; P=0.019).Conclusions: Compared with OHA, insulin therapy may be associated with DR, DR severity and DME in these T2DM sub-Saharan African patients.

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“…Diabetes mellitus is becoming a major health issue by presenting two major problems namely increase in the number of diabetics and increase in the prevalence of disastrous long term complications resulting in amputations, cardiovascular disorders, end stage renal [15][16][17][18][19][20] disease and blindness [1]. DR is the leading cause of blindness in long-standing patients of diabetes mellitus [9] and is responsible for ~ 10,000 new blind cases each year in USA alone [17] between the ages of 20 to 75 years [21].…”

Section: Discussionmentioning

confidence: 99%

“…DR is the leading cause of blindness in long-standing patients of diabetes mellitus [9] and is responsible for ~ 10,000 new blind cases each year in USA alone [17] between the ages of 20 to 75 years [21].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of diabetic retinopathy in type II diabetic patients in a health facility in Karachi, Pakistan

Ishaq¹,

Ali²,

Kazmi³

et al. 2016

Trop. J. Pharm Res

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Prevalence of diabetic retinopathy in Tehran province: a population-based study

Abstract: Background: To determine the prevalence and characteristics of diabetic retinopathy (DR) among Iranian patients with diabetes.

Cited by 93 publications

References 36 publications

Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital – based Cross – Sectional Study

Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital – based Cross – Sectional Study

Association of insulin treatment versus oral hypoglycaemic agents with diabetic retinopathy and its severity in type 2 diabetes patients in Cameroon, sub-Saharan Africa

Prevalence of diabetic retinopathy in type II diabetic patients in a health facility in Karachi, Pakistan

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