Prevalence of distal renal tubular acidosis in patients with calcium phosphate stones

Guimerà, J.; Martínez, Ana Almansa; Tubau, V.; Sabate, Arnau; Bauzá, Jose Luis; Ríos, Ángel; López, Meritxell; Piza, Pedro de Toledo; Gráses, F.; Pieras, Enrique

doi:10.1007/s00345-019-02804-9

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…We also added potassium-citrate being a chelate of urinary calcium and inhibiting calcium phosphate lithiasis crystallization. 4 Additionally, we added phytate owing to its capacity to inhibit calcium phosphate lithiasis growth and to decrease bone resorption. 5 …”

Section: Discussionmentioning

confidence: 99%

Recurring renal lithiasis due to Dent’s disease

Amer-Mestre,

Guimerà-García,

Guldris-García

et al. 2023

Urology Case Reports

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Section: Discussionmentioning

confidence: 99%

Recurring renal lithiasis due to Dent’s disease

Amer-Mestre,

Guimerà-García,

Guldris-García

et al. 2023

Urology Case Reports

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“…[ 15 , 16 ] Recently, Guimerà et al . [ 17 ] showed that renal tubular acidosis has been confirmed as a pathogenic factor for urinary calculi, and although calcium oxalate stones are the dominant type of urinary calculi among the general population, calcium phosphate stones are most common in individuals with renal tubular acidosis. A retrospective study showed that there was a high prevalence of urolithiasis among patients with thin basement membrane nephropathy, mainly in the presence of hypercalciuria and hyperuricosuria [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…The urinary pH > 6 often indicates a diagnosis of suspected renal tubular acidosis, although an acidification test is needed. Several other studies [ 17 , 23 , 24 ] have also shown that the prevalence of kidney stones was significantly higher in individuals with high urinary pH levels than in those with normal urinary pH and tended to be correlated with calcium phosphate stones, which easily recur and form staghorn stones [ 25 ]. These findings may explain why the incidence of staghorn stones in HbsAg-positive UUC patients in this study was higher than that in HbsAg-negative UUC patients.…”

Section: Discussionmentioning

confidence: 99%

Chronic hepatitis B virus infection increases the risk of upper urinary calculi

2022

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Background Although hepatitis B virus (HBV) is a recognized risk factor for renal diseases, little is known about HBV infection in individuals with upper urinary calculi (UUC). We investigated the relationship between chronic HBV infection and UUC. Methods We retrospectively analysed data from 1399 patients who were discharged from the Department of Urology (2017–2018). The diagnosis of UUC was determined using urinary tract ultrasonography or computed tomography, and HBV infection was evaluated by a positive hepatitis B surface antigen (HBsAg) test. Data on patients with and without UUC and HBsAg-positive and HBsAg-negative patients were compared by univariate and multivariate analyses. Results Data on chronic HBV infection and UUC were available for 1062 patients, including 514 who presented with UUC and 548 who did not. Overall, 5.8% of total patients, 8.0% of UUC patients and 3.8% of non-UUC patients had chronic HBV infection. UUC patients (41/514) had a significantly higher prevalence of HBsAg positivity (OR 2.175; 95% CI 1.267–3.734; P = 0.004) than non-UUC patients (21/548). After stratifying by sex, the relative odds of HBsAg positivity were statistically significant in men (OR 2.156; 95% CI 1.162–4.003; P = 0.015) but not in women (OR 2.947; 95% CI 0.816–10.643; P = 0.099). The incidence of urinary pH > 6 and staghorn stones was significantly higher in HBsAg-positive UUC patients than in HBsAg-negative UUC patients. Conclusion This is the first study to demonstrate that chronic HBV infection is strongly associated with UUC, at least in men. The urinary pH > 6 and staghorn stones were more common in UUC patients with chronic HBV infection.

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Carbon composite thermoplastic electrodes integrated with mini-printed circuit board for wireless detection of calcium ions

Özer

2022

ANAL. SCI.

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Prevalence of distal renal tubular acidosis in patients with calcium phosphate stones

Cited by 7 publications

References 19 publications

Recurring renal lithiasis due to Dent’s disease

Recurring renal lithiasis due to Dent’s disease

Chronic hepatitis B virus infection increases the risk of upper urinary calculi

Carbon composite thermoplastic electrodes integrated with mini-printed circuit board for wireless detection of calcium ions

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