Prevalence of Duchenne and Becker Muscular Dystrophies in the United States

Abstract

Dr Romitti directed the surveillance and survey data collection in Iowa, led the study design, directed the statistical analyses, drafted the initial manuscript, and revised manuscript drafts; Dr Zhu performed statistical analysis, contributed to the initial draft, and reviewed and revised manuscript drafts; Mr Puzhankara assisted with the study design, performed initial statistical analyses, and reviewed and revised manuscript drafts; Dr James performed statistical analysis, and reviewed and revised manuscript drafts; Dr Nabukera assisted with data collection in Iowa, and reviewed and revised manuscript drafts; Dr Zamba assisted with the study design, assisted with the statistical analyses and prevalence estimation, and reviewed and revised manuscript drafts; Dr Ciafaloni contributed to the development of case definitions, led the development of the Duchenne and Becker phenotype classification, conducted clinical review of cases, and reviewed manuscript drafts; Drs Cunniff and Meaney codirected the surveillance and survey data collection in Arizona, assisted in conceptualization and design of the study, and reviewed and revised manuscript drafts; Dr Druschel directed the surveillance and survey data collection in New York, provided input and feedback on analyses, and reviewed and revised manuscript drafts; Dr Mathews led the development of case definitions, conducted clinical review of cases, and reviewed and revised manuscript drafts; Dr Matthews contributed to the development of case definitions, led the multisite clinical review committee and assignment of case definitions, conducted clinical review of cases, and reviewed manuscript drafts; Ms Andrews coordinated and supervised data acquisition in Arizona, and reviewed and revised manuscript drafts; Dr Caspers Conway assisted with oversight of data acquisition in Iowa, provided input and feedback on analyses, and reviewed and revised manuscript drafts; Ms Fox assisted with oversight of data collection in New York, provided input and feedback on analyses, and reviewed and revised manuscript drafts; Ms Street coordinated and supervised data acquisition in Georgia, and reviewed and revised manuscript drafts; Dr Adams reviewed and revised manuscript drafts; Dr Bolen coordinated the Muscular Dystrophy Surveillance, Tracking, and Research Network for the Centers for Disease Control and Prevention, and reviewed and revised manuscript drafts; and all authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. FINANCIAL DISCLOSURE:The other authors have indicated they have no financial relationships relevant to this article to disclose. POTENTIAL CONFLICT OF INTEREST:The other authors have indicated they have no potential conflicts of interest relevant to this article to disclose. 1991-1995, 1996-2000, 2001-2005, and 2006-2010) and prevalence per 10 000 male individuals, ages 5 to 24 years, in 2010. Prevalence was also estimated by race/ethnicity and phenotype. HHS Public AccessRESULTS-Overall, 649 cases resided in an...