Prevalence of Duchenne and Becker Muscular Dystrophies in the United States

Romitti, Paul A.; Zhu, Yong; Puzhankara, Soman; James, Katherine A.; Nabukera, Sarah K.; Zamba, Gideon; Ciafaloni, Emma; Cunniff, Christopher; Druschel, Charlotte M.; Mathews, Katherine D.; Matthews, Dennis J.; Meaney, F. John; Andrews, Jennifer; Conway, Kristin M; Fox, Deborah; Street, Natalie; Adams, Melissa M.; Bolen, Julie

doi:10.1542/peds.2014-2044

Cited by 249 publications

(165 citation statements)

References 41 publications

Supporting

Mentioning

148

Contrasting

Unclassified

Order By: Relevance

“…7 In 2015, it was determined that the combined prevalence of DMD and Becker's muscular dystrophy (BMD) (another prevalent dystrophy) among boys aged 5-9 was about 2 in 10,000. 8 Although DMD is the most common, there are many other dystrophies. BMD is very similar to DMD, and results in partially functional dystrophin.…”

Section: Wasting Diseases and Disordersmentioning

confidence: 99%

Engineering Approaches for Creating Skeletal Muscle

Vogt¹,

Tahtinen²,

Zhao³

2017

Tissue Engineering and Nanotheranostics

View full text Add to dashboard Cite

Engineered skeletal muscle grafts have made great progress during the past decades, benefiting from a growing understanding of mechanobiology and stem cell differentiation. Current techniques are widely varied, ranging from in vitro methods following the classical tissue engineering paradigm to in situ approaches such as host cell recruitment. In different ways, all of these try to supply mechanical toughness while providing the necessary signals for differentiation and maturation of the engineered skeletal muscle.

show abstract

Section: Wasting Diseases and Disordersmentioning

confidence: 99%

Engineering Approaches for Creating Skeletal Muscle

Vogt¹,

Tahtinen²,

Zhao³

2017

Tissue Engineering and Nanotheranostics

View full text Add to dashboard Cite

show abstract

“…There are several types of muscular dystrophies that differ in severity, onset, and genetic causes; the Duchenne Muscular Dystrophy (DMD) is the most aggressive and prevalent type. The estimated prevalence of DMD is 1 in every 7,250 males aged 5-24 years, and the total time of diagnosis is 2.5 years [5]. At the age 2½-years-old the first signs or symptoms are noticed by a parent or caregiver.…”

Section: Introductionmentioning

confidence: 99%

Iron Determination in Whole Blood Samples of Dystrophic Mouse Strains Using X-Ray Fluorescence Spectrometry

Giovanni¹,

Metairon²,

Zamboni³

et al. 2017

J Musculoskelet Disord Treat

View full text Add to dashboard Cite

Several diseases can be monitored by assessing the variation of specific ion concentration in body fluids. This study proposes an alternative analysis, based on the X-ray fluorescence spectrometry technique, for the investigation of iron (Fe concentration determination) in whole blood of the dystrophic animal models. We performed blood analyses from three different strains with Muscular Dystrophy (Dmd mdx /J, SJL/J and A/J) and from healthy (C57BL/6J) mice strain adopted as the control group. The results emphasize that iron levels in whole blood male samples of SJL/J and A/J are significantly higher. Related to the gender for Dmd mdx /J and SJL/J mouse strains the comparison emphasizes that iron level increase for males. The study of Fe behavior in whole blood mice samples with muscular dystrophy contributes to its diagnosis, providing a better understanding of this disease.

show abstract

“…In 2010, prevalence of DBMD was estimated at 1.38 per 10,000 males, ages 5 to 24 years (Romitti et al, 2015). The two conditions have similar signs and symptoms; however, they differ in age of onset, rate of progression, and severity.…”

Section: Introductionmentioning

confidence: 99%

A Cross-Sectional Study of School Experiences of Boys with Duchenne and Becker Muscular Dystrophy

Soim

Lamb

Campbell

et al. 2016

PDERS

View full text Add to dashboard Cite

Abstract:The objectives of this study were to investigate types of supportive school services received and factors related to provision of these services. We conducted a cross-sectional study to describe the school experience of males with Duchenne and Becker muscular dystrophies. Study subjects were identified through the Muscular Dystrophy Surveillance, Tracking, and Research Network. Non-ambulatory males with Duchenne muscular dystrophy (DMD) were significantly more likely to use an instructional assistant and resource room Soim et al. 2support when compared to ambulant males with DMD at the time of the caregiver interview. Males with DMD who received occupational therapy were more likely to use an instructional assistant, while those who received speech therapy were more likely to repeat a grade, use an instructional assistant, and receive resource room support. Males with DMD whose primary caregivers had less than 12 years of education were more likely to use an instructional assistant and resource room support. Non-ambulatory males with DMD should continue receiving appropriate school accommodations so they can keep pace with their physical demands. Males with DMD with speech deficits should be considered for various educational interventions.

show abstract

Prevalence of Duchenne and Becker Muscular Dystrophies in the United States

Cited by 249 publications

References 41 publications

Engineering Approaches for Creating Skeletal Muscle

Engineering Approaches for Creating Skeletal Muscle

Iron Determination in Whole Blood Samples of Dystrophic Mouse Strains Using X-Ray Fluorescence Spectrometry

A Cross-Sectional Study of School Experiences of Boys with Duchenne and Becker Muscular Dystrophy

Contact Info

Product

Resources

About