Prevalence of Filaria Worm Amongprospective Blood Donors Attending a Tertiary Health Institution In Southwestnigeria

Ojo-Bola, T.; Omisakin, C. T.; Esan, Arinola; Owoseni, M. F

doi:10.9790/0853-13158487

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Among all the variables examined in this study, only the age group 18-28 was significantly associated microfilaria (OR = 8.83; 95% CI = 1.09 -71.35; P-value ˂ 0.05). This finding is in line with that of Bola et al who reported the highest microfilaria prevalence in the age group 21-30 [39]. This could be explained by the fact that the majority (5/8) of the responders who tested positive falls within this age range and have reported to frequently stay in the villages.…”

Section: Prevalence Of Anemia Among Blood Donor Candidatessupporting

confidence: 92%

“…Microfilaria worms were detected in 2.68% (12/447) of prospective donors; of which 1.56 % (n = 7) were Loa loa and 1.12% (n = 5) Mansonella perstans (Table 2). This result is similar to the rates of (1.04% -1.33 %) and (0.33% -0.58%) reported respectively for Loa loa and M. perstans in two separate studies conducted in Nigeria [39,40]. Among all the variables examined in this study, only the age group 18-28 was significantly associated microfilaria (OR = 8.83; 95% CI = 1.09 -71.35; P-value ˂ 0.05).…”

Section: Prevalence Of Anemia Among Blood Donor Candidatessupporting

confidence: 90%

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Prevalence of Haemoparasites among Blood Donors Attending the Regional Hospital Center of Franceville (Southern Gabon)

Moundounga¹,

Bourdettes²,

Thièry³

et al. 2022

J Infect Dis Epidemiol

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Background: Blood donation is a lifesaving intervention and a precious gift for patients in urgent need. However, the blood should be carefully checked for transfusion-transmitted infections such as HIV, hepatitis, syphilis, malaria and other endemic haemoparasites. In Gabon, like in many other African countries, blood is not routinely screened for malaria as recommended by the World health organization. Objective:The main objective of this study was to screen the blood of prospective donors attending Amissa Bongo Regional Hospital Center of Franceville (Southern Gabon) for blood-borne parasites.Methods: Blood donor candidates were subjected to a structured questionnaire and haemoparasites detected using microscopic examinations: direct examination and cytoconcentration technique for filarial worms, thick blood smears and direct examination for Babasia spp and Trypanosoma spp, SD Bioline Malaria AG P.F/PAN Test and thick/thin blood smears for Plasmodium falciparum. Results:The majority of blood donor candidates were males, family donors, work in the informal sector, and under 39 years old. The results also revealed that the prevalences of malaria parasites (Plasmodium falciparum) and filarial worms (Loa loa and Mansonella perstans) were respectively 5.59% (51/447) and 2.68% (12/447). In contrast, none of the prospective blood donors tested positive for Babesiosis or African Trypanosomiaisis. Family blood donors were more affected with malaria compare voluntary donors (OR = 1.45; 95% CI = 0.42 -5.00). The age group 18-28 was statistically most affected by the filarial infection than the other groups (OR = 8.83; 95% CI = 1.09 -71.35; P-value = 0.0411). The results also showed that more than one third of prospective donors suffered from anemia. However, there was no significant association with either malaria or microfilaria (P-value ˃ 0.05). Conclusion:The current hospital-based study detected Plasmodium falciparum and filarial worms among prospective blood donors. This finding that raises concerns should draw the attention of local health authorities and lead them to routinely screen blood for malaria parasites as recommended by the world health organization.

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Section: Prevalence Of Anemia Among Blood Donor Candidatessupporting

confidence: 92%

Section: Prevalence Of Anemia Among Blood Donor Candidatessupporting

confidence: 90%

Prevalence of Haemoparasites among Blood Donors Attending the Regional Hospital Center of Franceville (Southern Gabon)

Moundounga¹,

Bourdettes²,

Thièry³

et al. 2022

J Infect Dis Epidemiol

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Prevention strategies of transfusion-transmitted parasitic infections (TTPIs): Strengths and challenges of current approaches, and evaluation of the strategies implemented in Iran

Mardani

2020

Parasite Epidemiology and Control

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Filariasis and transfusion‐associated risk: a literature review

et al. 2021

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Background and objectives Filariae are parasitic worms that include the pathogens Loa loa, Onchocerca volvulus, Wuchereria bancrofti, Brugia spp. and Mansonella spp. which are endemic in parts of Africa, Asia, Asia‐Pacific, South and Central America. Filariae have a wide clinical spectrum spanning asymptomatic infection to chronic debilitating disease including blindness and lymphedema. Despite successful eradication programmes, filarial infections remain an important –albeit neglected – source of morbidity. We sought to characterize the risk of transfusion transmission of microfilaria with a view to guide mitigation practices in both endemic and non‐endemic countries. Materials and methods A scoping review of scientific publications as well as grey literature was carried out by a group of domain experts in microbiology, transfusion medicine and infectious diseases, representing the parasite subgroup of the International Society of Blood Transfusion. Results Cases of transfusion‐transmitted filariasis are rare and confined to case reports of variable quality. Transfusion‐associated adverse events related to microfilariae are confined to isolated reports of transfusion reactions. Serious outcomes have not been reported. No known strategies have been implemented, specifically, to mitigate transfusion‐transmitted filariasis yet routine blood donor screening for other transfusion‐transmissible infections (e.g. hepatitis B, malaria) may indirectly defer donors with microfilaremia in endemic areas. Conclusion Rare examples of transfusion‐transmitted filariasis, without serious clinical effect, suggest that filariasis poses low transfusion risk. Dedicated mitigation strategies against filarial transfusion transmission are not recommended. Given endemicity in low‐resource regions, priority should be on the control of filariasis with public health measures.

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Prevalence of Filaria Worm Amongprospective Blood Donors Attending a Tertiary Health Institution In Southwestnigeria

Abstract: The prevalence of microfilaria parasite was carried out among prospective blood donors at FederalMedical Centre (FMC)

Cited by 4 publications

References 6 publications

Prevalence of Haemoparasites among Blood Donors Attending the Regional Hospital Center of Franceville (Southern Gabon)

Prevalence of Haemoparasites among Blood Donors Attending the Regional Hospital Center of Franceville (Southern Gabon)

Prevention strategies of transfusion-transmitted parasitic infections (TTPIs): Strengths and challenges of current approaches, and evaluation of the strategies implemented in Iran

Filariasis and transfusion‐associated risk: a literature review

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