Prevalence of Gallstone Disease in a General Population of Okinawa, Japan

Nomura, Hideyuki; Kashiwagi, Seizaburo; Hayashi, Jun; Kajiyama, Wataru; Ikematsu, Hideyuki; Noguchi, Akinori; Tani, Shunichi; Goto, Masashi

doi:10.1093/oxfordjournals.aje.a115007

Cited by 123 publications

(66 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Epidemiological data have revealed that in the general population, the overall prevalence range of gallstones is 3.29%-14.85% (10)(11)(12)(13), and the overall prevalence range of NAFLD is 14%-40%. The pooled prevalence of GD in the NAFLD group in the present meta-analysis was 17%, which is higher than in the general population.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Promotional effect of nonalcoholic fatty liver disease on Gallstone disease: A systematic review and meta-analysis

Shen¹,

Gong²,

Wang³

et al. 2020

Turk J Gastroenterol

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

“…The overall prevalence of gallstones is approximately 3.29%-14.85% in the general population (10)(11)(12)(13). Increased age, female sex, obesity, metabolic syndrome, hypertriglyceridemia, diabetes and insulin resistance are major risk factors for gallstones (10,14).…”

Section: Introductionmentioning

confidence: 99%

Promotional effect of nonalcoholic fatty liver disease on Gallstone disease: A systematic review and meta-analysis

Shen¹,

Gong²,

Wang³

et al. 2020

Turk J Gastroenterol

View full text Add to dashboard Cite

“…In conclusion, the suggestion that changing lifestyles and industrialization are probable causes of excess gallstone disease is to be discouraged as despite the economic dominance of Japan, gallstone prevalence there remained low [49]. A larger scale, perhaps nationwide, preferably population-based study will be needed to confirm our findings and to further assess possible genetic and/or environmental factors as possible causes for the formation of gallstones in Saudi females at a young age.…”

Section: Annals Of Saudi Medicine Vol 12 No 4; 1992mentioning

confidence: 67%

Risk Factors for Gallstone Formation in Young Saudi Women: A Case Control Study

Ahmed¹,

Elhassan

Mahmoud³

1992

Ann Saudi Med

View full text Add to dashboard Cite

One hundred eighty-three young Saudi females (92 patients with gallstones, 91 controls) mean age and (SD), 30.2 (6.1) and 29.7 (6.4) years respectively were studied in detail for possible risk factors for gallstone formation. No statistically significant difference was found when the two groups were compared with regard to past history of jaundice, HBsAg carrier status, use of oral contraceptives, parity, diabetes mellitus, obesity (as Body Mass Index > 30), hypercholesterolemia and hypertriglyceridemia. However, it was noted that both groups were overweight; mean (SD) BMI of 27 (5.9) and 26.7 (6.8) for patients and controls respectively and both had high parity rates; mean and (SD) pregnancies of 4.7 (2.6) and 4.3 (2.9), respectively. Family history of gallstones in first degree relatives of patients was significant (.0027 < P < .01) more than in the controls (95% confidence interval of 3% to 23% ). This may suggest a genetic or an environmental factor that strikes the balance toward gallstone formation in the obese and fertile young female population. A larger nationwide, population-based study is surely justified and needed. AF Ahmed, OM El-Hassan, ME Mahmoud, Risk Factors for Gallstone Formation in Young Saudi Women: A Case Control Study. 1992; 12(4): 395-399 It is our impression that gallstones are remarkably common in Saudis; no exact prevalence figures are available.Comparison of the prevalence of gallstones among different populations is notoriously difficult not only because of differences in availability of diagnostic facilities and attitudes toward treatment, but many patients who have gallstones remain symptom-free [1]. Thus, in Britain, only one in seven individuals with gallstones results in cholecystectomy [2], whereas in one population-based Italian study, 78% of subjects found to have gallstones were asymptomatic [3].According to our local statistics in Almadinah Almounawarah, approximately 350 to 400 cholecystectomies are performed each year in King Fahd Hospital and Ohud Hospital (Al-madinah Almounawarah's two main Ministry of Health (MOH) general referral hospitals, bed capacity 500 and 200, respectively); approximately 50% of elective laparotomies. A similar rate was reported from Riyadh, Saudi Arabia [4].Gallstone risk factors that could not be manipulated were female sex and advanced age [5][6][7][8][9]. We report a case control study of Saudi females, younger than 40 with and without gallstones; in relation to the following factors: parity, contraceptive pill, previous liver disease and HBsAg carrier state, family history of gallstones, obesity, diabetes mellitus, plasma lipids and total cholesterol and triglycerides. Subjects and Methods Definition of Cases and ControlsSaudi females younger than 40 who had a positive abdominal ultrasound scan for gallstones (cases) and sexand age-matched subjects with negative scan (controls) were studied. The presence or absence of symptoms or other diseases were not considered as an inclusion or exclusion criteria in selection of the cases and the...

show abstract

“…In the present study, the prevalence of synchronous gallstones was 4% in the nonresectable group and 5.5% in those undergoing surgical resection, showing no significant difference. The prevalence of gallstones in the general middleage population in Japan is about 5% (18) and increases to about 10% in the elderly (19). These results indicate that the prevalence of gallstones after esophagectomy may be low compared with that after gastrectomy, and may be almost the same compared with that of the general population.…”

Section: Discussionmentioning

confidence: 88%

Acute Cholecystitis and Cholelithiasis Developed after Esophagectomy

Tachibana

Kinugasa

Yoshimura

et al. 2003

Canadian Journal of Gastroenterology

View full text Add to dashboard Cite

BACKGROUND: Although the prevalence of gallstone disease after gastrectomy is reported to be high, its prevalence after esophagectomy is scarcely reported.MATERIALS AND METHODS: Gallbladder disease following an esophagectomy was prospectively evaluated in 237 patients with esophageal cancer by abdominal ultrasonography twice a year up to five years postoperatively. The median follow-up period was 18.6 months.RESULTS: One patient (0.4%) developed acute acalculous cholecystitis postoperatively, and 13 patients (5.5%) developed gallstone disease during the follow-up period. Nine (69%) of these 13 patients developed gallstone disease within two years, and another two patients developed the disease three years after esophagectomy. Another patient developed gallbladder debris at 35 months postoperatively, and one developed gallbladder polyps at 33 months. Seven of the 13 patients with gallstone disease underwent cholecystectomy between 13 and 125 months after esophagectomy: two developed acute cholecystitis; two had associated common bile duct stones; the remaining three patients had upper abdominal pain. Nine of the 13 patients who developed gallstone disease showed a history of alcoholism, whereas only 81 of 224 patients without gallstone disease had a similar history (P<0.05).CONCLUSION: A certain number of patients with esophageal carcinoma and a history of alcoholism develop cholelithiasis within three years after esophagectomy, and subsequently undergo cholecystectomy during the follow-up period.

show abstract

Prevalence of Gallstone Disease in a General Population of Okinawa, Japan

Cited by 123 publications

References 0 publications

Promotional effect of nonalcoholic fatty liver disease on Gallstone disease: A systematic review and meta-analysis

Promotional effect of nonalcoholic fatty liver disease on Gallstone disease: A systematic review and meta-analysis

Risk Factors for Gallstone Formation in Young Saudi Women: A Case Control Study

Acute Cholecystitis and Cholelithiasis Developed after Esophagectomy

Contact Info

Product

Resources

About