Prevalence of gestational diabetes mellitus and the effect of weight on measures of insulin secretion and insulin resistance in third‐trimester pregnant rural women residing in the Central Region of Limpopo Province, South Africa

Mamabolo, Ramoteme L.; Alberts, Marianne; Levitt, Naomi; Waal, Henriëtte A. Delemarre-van de; Steyn, Nelia P.

doi:10.1111/j.1464-5491.2006.02073.x

Cited by 49 publications

(61 citation statements)

References 37 publications

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“…The current study, employing the revised WHO diagnostic criteria, gives an overall prevalence rate of 13.4% among these women with identified risk factors. A South African study, also using the same criteria, reported a prevalence rate of 8.8% among a group of 262 third trimester pregnant women 8. Our value is however much lower than reported among similarly selectively screened women in western India, where a rate of 21.6% was observed 9.…”

Section: Discussioncontrasting

confidence: 48%

Oral glucose tolerance testing outcomes among women at high risk for gestational diabetes mellitus

et al. 2011

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Section: Discussioncontrasting

confidence: 48%

Oral glucose tolerance testing outcomes among women at high risk for gestational diabetes mellitus

et al. 2011

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“…Mothers who develop gestational diabetes mellitus have an increased risk of developing type 2 diabetes mellitus, and infants born to mothers who have gestational diabetes mellitus are at an increased risk of adverse birth outcomes, including macrosomia and childhood obesity. 38-40 A reason for the low prevalence of gestational diabetes mellitus could be the low mean age (26.3 ± 5.4 years) of the women in this study, which is comparable with that of the women in a study by Mamabola et al 41 The highest proportion of women who developed gestational diabetes mellitus were categorised in the obesity group. This is in agreement with the findings of Mamabola et al, 41 who also reported that women who developed gestational diabetes mellitus were significantly heavier than those who did not.…”

Section: Discussionsupporting

confidence: 73%

An investigation into utilising gestational body mass index as a screening tool for adverse birth outcomes and maternal morbidities in a group of pregnant women in Khayelitsha

Davies

Visser

Tomlinson

et al. 2013

South African Journal of Clinical Nutrition

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Objective The aim of this study was to investigate the ability of the gestational body mass index (BMI) method to screen for adverse birth outcomes and maternal morbidities. Design This was a substudy of a randomised controlled trial, the Philani Mentor Mothers’ study. Setting and subjects The Philani Mentor Mothers’ study took place in a peri-urban settlement, Khayelitsha, between 2009 and 2010. Pregnant women living in the area in 2009-2010 were recruited for the study. Outcome measures Maternal anthropometry (height and weight) and gestational weeks were obtained at baseline to calculate the gestational BMI, which is maternal BMI adjusted for gestational age. Participants were classified into four gestational BMI categories: underweight, normal, overweight and obese. Birth outcomes and maternal morbidities were obtained from clinic cards after the births. Results Pregnant women were recruited into the study (n = 1 058). Significant differences were found between the different gestational BMI categories and the following birth outcomes: maternal (p-value = 0.019), infant hospital stay (p-value = 0.03), infants staying for over 24 hours in hospital (p-value = 0.001), delivery mode (p-value = 0.001), birthweight (p-value = 0.006), birth length (p-value = 0.007), birth head circumference (p-value = 0.007) and pregnancy-induced hypertension (p-value = 0.001). Conclusion To the best of our knowledge, this is the first study that has used the gestational BMI method in a peri-urban South African pregnant population. Based on the findings that this method is able to identify unfavourable birth outcomes, it is recommended that it is implemented as a pilot study in selected rural, peri-urban and urban primary health clinics, and that its ease and effectiveness as a screening tool is evaluated. Appropriate medical and nutritional advice can then be given to pregnant women to improve both their own and their infants’ birth-related outcomes and maternal morbidities.

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“…(Mamabolo et al 2007). Although the prevalence of GDM highly depends on method and criteria used, pre-pregnancy BMI, a strong predictor of GDM in other studies, (Schneider et al 2012;Mamabolo et al 2007) was not associated with GDM-perhaps due to differences in dietary behavioral factors and balance between nutrient metabolism and degree of adipogenesis, as well as innate genetic predisposition. Age and firstfamily history of diabetes were associated with GDM as consistently reported elsewhere (Aberg et al 2002).…”

Section: Discussionmentioning

confidence: 99%

Strategy to improve the burden of gestational diabetes in African women: Rwandan perspective

Mapira¹,

Tumusiime²,

Yarasheski³

et al. 2017

RWJour

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The global prevalence of gestational diabetes (GDM) in pregnant 20-49 year old women has increased to 16.9%, although data from Africa on GDM are scarce, and risk exposure to pregnant women is unknown. Among the 288 pregnant women screened in Rwanda, 8.3% of women with FPG >126 mg/dL (>6.9 mmol/L) had GDM. Age >41 years (45.8% vs. 18.9%; p<0.001), first-family history of T2D (29.2% vs. 3.4%; p<0.001) and gravidity ≥3 pregnancies (79.2% vs. 29.2%; p=0.05) were associated with GDM. Gestational diabetes is a high risk factor for T2D, and increases the risk to T2D for women and their offspring later in life. Thus, improving maternal and child cardiometabolic health in Africa is needed through integrated gestational diabetes screening, and cost-effective sustainable strategies to build healthcare staff capacity, and to prioritize relevant evidence-based research and healthcare.

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Prevalence of gestational diabetes mellitus and the effect of weight on measures of insulin secretion and insulin resistance in third‐trimester pregnant rural women residing in the Central Region of Limpopo Province, South Africa

Cited by 49 publications

References 37 publications

Oral glucose tolerance testing outcomes among women at high risk for gestational diabetes mellitus

Oral glucose tolerance testing outcomes among women at high risk for gestational diabetes mellitus

An investigation into utilising gestational body mass index as a screening tool for adverse birth outcomes and maternal morbidities in a group of pregnant women in Khayelitsha

Strategy to improve the burden of gestational diabetes in African women: Rwandan perspective

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