Prevalence of Gonococcal Infection Among the Patients Visiting at Dermatology/Venerology and Gynaecology Department of Tribhuvan University Teaching Hospital

Abstract

A substantial proportion of women with gonococcal infection are asymptomatic butsymptomatic in male. Thus in developing countries, problem arises in active casedetection where laboratory facilities for testing are limited. During the study, thediagnostic validity of the hierarchial clinical algorithm as well as that of a non-hierarchial scoring system were assessed among 102 patient visiting at Dermatology/Venerology (DV) and Gynecology(Gynae) out patient department(OPD) of TribhuvanUniversity Teaching Hospital (TUTH), Kathmandu, Nepal. In the study period of 8months, May –December 1999, 9 (8.82%) were infected with N. gonorrhoea& 2(1.96%)with Gram Negative intracellular diplococci. Age group of 20-30 years were found tobe more infected followed by age groups 30-40 years & 40-50 years ( P< 0.10). Themale were found to be predominantly infected than female and married were foundto be more infected than unmarried. Among the infected people most of them hadsecondary level education and least of them had higher level education. Service holderswere found to be more infected than farmers, drivers & others. But male serviceholders & housewives were equally infected.Antimicrobial susceptibility of N. gonorrhoeashowed 100% susceptible to Ceftriaxone,followed by Ciprofloxacin (88.88%) whereas 22.22% resistant to Tetracycline, 55.55%to Cotrimoxazole and 55.55% to Penicillin. Among isolates, 33.33% were ß- lactamaseproducer. Co-micro organisms like Candida sppand Staphylococcus sppwere alsoobserved.Key Words: Gonococcal infection; Outpatient department, Antimicrobial susceptibility, Nepal.