Prevalence of Helicobacter Pylori Among Asymptomatic Populations in Sana'a, Yemen

Alyahawi, Ali; Al-kaf, Ali Gamal Ahmed; Alzaghrori, Samar

doi:10.22270/ujpr.v3i3.163

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…Furthermore, the study of the metabolic syndrome prevalence according to sex showed a significantly higher prevalence in females (52.9%) %) compared to males (30.4%). This result is similar to many studies 17,18 . However, it was in consistent with others where the prevalence is similar between both sexes 19 .…”

Section: Discussionsupporting

confidence: 93%

Evaluation of Metabolic Syndrome in Healthy Yemeni Populations

Alrubaiee

Alyahawi

2020

Univ J Pharm Res

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The metabolic syndrome is characterized by several cardiovascular risk factors and is associated with an increased incidence of diabetes, cardiovascular events and mortality. The prevalence of metabolic syndrome is increasing in epidemic proportions worldwide. The present study aimed to investigate the prevalence of MS and its components in healthy populations in Sana'a, Yemen. This study was a cross-sectional study conducted from February 2019 to April 2019. A total of 120 healthy populations (>=40 years old) were selected. The study protocol was approved by the institutional ethical committee and informed consent was obtained from all the enrolled study patients for their inclusion in the screening and participation in the research. In the present study, the diagnosis of metabolic syndrome based on the American Heart Association/National Heart, Lung, and Blood Institute(AHA/NHL BI) and to a joint statement from several large organizations. In the current study, the presence of more than or equal to any three of the above mentioned factors is required for the diagnosis of metabolic syndrome. The total prevalence of MS among the study subjects was 40.0% (P< 0.001) and 62.5%of them were within 40-49 years old. In the present study, there was not statically significant difference between the khat chewing and the metabolic syndrome. According the distribution of metabolic syndrome criteria among subjects with metabolic syndrome, the prevalence of fasting blood glucose (FBG) was the highest (85%). The prevalence of metabolic syndrome among healthy Yemeni populations was very high and it is associated with increased morbidity and mortality. This emphasizes the need for more attention to investigate this condition to decreasing the prevalence of cardiovascular morbidity and mortality in these subjects. Peer Review History: UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Hassan A.H. Al-Shamahy Affiliation: Sana'a University, Yemen E-mail: shmahe@yemen.net.ye Name: Dr. Muhammad Shahzad Aslam Affiliation: Universiti Malaysia Perlis, Malaysia E-mail: aslam.shahzad@xmu.edu.my Comments of reviewer(s): Similar Articles: PREVALENCE OF HEPATITIS G VIRUS AMONG PATIENTS WITH CHRONIC LIVER DISEASE AND HEALTHY INDIVIDUALS, SANA'A CITY-YEMEN

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Section: Discussionsupporting

confidence: 93%

Evaluation of Metabolic Syndrome in Healthy Yemeni Populations

Alrubaiee

Alyahawi

2020

Univ J Pharm Res

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“…In addition, our study shows Khat chewing to be a risk factor for H. pylori infection, which is in agreement with earlier studies reporting the prevalence of H. pylori infection to be higher among Khat chewers, indicating that Khat chewing could be a predisposing factor to gastrointestinal disorders and H. pylori infection. 24,37,[39][40][41] Khat chewers were reported to be four times more likely to have H. pylori infection than non-Khat chewers. 37 The high prevalence of H. pylori with Khat chewing would also be expected to reduce iron absorption, [42][43][44] since H. pylori increases iron uptake and utilization for metabolism 45 and also leads to blood loss due to gastric lesions as a consequence of infection, 46 and elevates the pH of gastric juice due to infection.…”

Section: Discussionmentioning

confidence: 99%

Association between Chewing Khat (Catha edulis) and Hematological Indices and Helicobacter pylori Infection and Blood Loss in the Gastrointestinal Tract of Yemeni Chewers.

Al-Absi,

Al-Dubai,

Al-Ghazaly

et al. 2024

jchm

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Background: The available data on the effect of Khat chewing on hematological indices are conflicted and mainly based on animal studies. The aim of this study was therefore to investigate the effect of Khat chewing on hematological indices in humans as well as the possible association of Khat chewing with H. pylori infection and blood loss in the gastrointestinal tract. Patients and Methods: This study was a comparative cross-sectional study, carried out on 140 participants aged 18 - 55 years old; 71 were healthy non-Khat chewers serving as a control group and 69 were regular Khat chewers. Complete blood count was analyzed as well as H. pylori antigen and occult blood in stool were investigated. Results: Hemoglobin concentration, MCV, MCH, and PCV were significantly (p = 0.037, 0.034, 0.043, and 0.019 respectively) lower in Khat chewers as compared with non-Khat chewers, whereas platelets count and white blood cells count were significantly (p = 0.006 and 0.007 respectively) higher in Khat chewers. Khat chewing was also associated with H. Pylori infection (OR: 2.7) and blood loss in the gastrointestinal tract (OR: 3.2). Conclusion: Khat chewing adversely affects hematological indices and increases the risk of H. Pylori infection and blood loss in the gastrointestinal tract.

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Diagnostic value of IgG antibody and stool antigen tests for chronic Helicobacter pylori infections in Ibb Governorate, Yemen

Al Ofairi,

Saeed,

Al-Qubaty

et al. 2024

Sci Rep

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The stool antigen test (SAT) and the serum Helicobacter pylori (H. pylori) IgG antibody assays exhibit significant utility in the clinical diagnosis of H. pylori infection and in distinguishing between acute and chronic infections. The main objective of the current study was to identify the diagnostic value of serum H. pylori IgG antibody and SAT in the detection of H. pylori infections among chronic H. pylori-infected patients residing in Ibb Governorate, Yemen. 200 patients with H. pylori infection, confirmed through positive results in the serum immunochromatographic antibody test, were selected for H. pylori infection confirmation using serum H. pylori IgG antibodies and SAT across diverse hospitals, gastroenterology, and Hepatology clinics in Ibb Governorate. After the selection of patients, blood and stool specimens were obtained from all participants and underwent analysis via the Statistical Package for the Social Sciences (SPSS). The prevalence of H. pylori infection demonstrated variability based on the confirmatory tests, with rates of 54% for SAT and 78.5% for serum H. pylori IgG antibody, contrasting with a 100% prevalence observed in the screening serum immunochromatographic antibody test. Clinically, the study categorized H. pylori infections into four stages, whereby a significant proportion of patients (40.5%) exhibited positivity for both serum H. pylori IgG antibody and SAT, indicative of active chronic infections. The majority of positive cases only manifested serum H. pylori IgG antibody presence (chronic infections) at 38%, whereas 13.5% exclusively tested positive for SAT, corresponding to acute infections. Moreover, 88% of patients did not have either serum H. pylori IgG antibody or SAT (absence of infections) during confirmatory tests. Noteworthy is the study's approach employing multiple tests for H. pylori infection detection, focusing predominantly on chronic infections-prevailing types caused by H. pylori. The results revealed a significant association between serum levels of H. pylori IgG antibody and SAT results with the presence of diverse gastrointestinal symptoms among patients, which increased with long H. pylori infection durations.

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Prevalence of Helicobacter Pylori Among Asymptomatic Populations in Sana'a, Yemen

Cited by 4 publications

References 19 publications

Evaluation of Metabolic Syndrome in Healthy Yemeni Populations

Evaluation of Metabolic Syndrome in Healthy Yemeni Populations

Association between Chewing Khat (Catha edulis) and Hematological Indices and Helicobacter pylori Infection and Blood Loss in the Gastrointestinal Tract of Yemeni Chewers.

Diagnostic value of IgG antibody and stool antigen tests for chronic Helicobacter pylori infections in Ibb Governorate, Yemen

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