Prevalence of Helicobacter pyloriinfection among new outpatients with dyspepsia in Kuwait

Abstract

BackgroundTesting and treatment for Helicobacter pylori has become widely accepted as the approach of choice for patients with chronic dyspepsia but no alarming features. We evaluated H. pylori status among outpatients with uninvestigated dyspepsia in Kuwait.MethodsA prospectively collected database for 1035 patients who had undergone 13C-urea breath tests (UBT) for various indications was reviewed for the period from October 2007 to July 2009. The status of H. pylori in dyspeptic patients was determined by UBT.ResultsAmong the 362 patients who had undergone UBT for uninvestigated dyspepsia, 49.7% were positive for H. pylori (95% CI = 44%-55%) and the percentage increased with age (35.8% at 20-29 years, 95% CI = 25.4% - 47.2%; 59.3% at 30-39 years, 95% CI = 48.5% - 69.5%) (P = 0.013). The prevalence of H. pylori was 42.6% among Kuwaitis (95% CI = 35%-50%) and 57.6% (95% CI = 49.8%-65%) among expatriates (p = 0.004). The prevalence among males was 51.3%, while in females it was 48.6%.ConclusionsAlmost half of the patients with dyspeptic symptoms in Kuwait were positive for H. pylori, though the prevalence varied with age and was higher among expatriates. The American Gastroenterology Association guidelines recommending testing and treatment for H. pylori for patients with uninvestigated dyspepsia should be endorsed in Kuwait.

Clinical, Endoscopic and Urea Breath Test Among Dyspeptic Patients Referred to Kurdistan Center for Gastroenterology and Hepatology in Sulaimani

“…There are different reports about the prevalence rate of this infection between countries, but interestingly, the results of this study (51.2%) which is compatible to the local study done in Hawler, Kurdistan by Bashdar M. Hussein et al [36] which is (55.8%) and showed the same prevalence of H. pylori in comparison with other reports from Asia and Middle East, such as the result of Alazmi et al [37]. research in Kuwait and Goh [38] in Malaysia, (49.7% and 49.0% respectively).…”

Validation of diagnostic tests and epidemiology of Helicobacter pylori infection in Bangladesh

“…When culture was used as a gold standard, the sensitivities and the specificities of serological tests were 80-95% and 80-95% respectively [15] and with histology as a gold standard the sensitivities were ranging from 76% to 84% and the specificities were ranging from 79% to 90% [35].The overall performance of serology against predefined gold standard in our study was not satisfactory. It differs from previous study conducted on 45 Bangladeshi patients where the sensitivity, specificity, and positive and negative predictive values were 100%, 13.6%, 54.8% and 100% for serological test against culture [25]. One possible explanation is the type of antigen used in the test kits was not similar.…”

Prevalence and predictors of Helicobacter pylori infection among patients attending a healthcare facility in North-Central Nigeria

“…However, the prevalence of this present study is lower than report from Ghana which recorded a prevalence of 75.4% among dyspeptic patients [4], reports from Saudi Arabia and Kuwait showing the prevalences of 68% and 62%, respectively [14,15]. to which the bacterium attaches, which also facilitates colonization of the bacterium [17].…”