Prevalence of hepatitis B and C virus infections among patients with chronic hepatitis at Bereka Medical Center, Southeast Ethiopia: a retrospective study

Abstract

BackgroundViral hepatitis exists throughout the world and is a major global public health problem affecting millions of people. Hepatitis B (HBV) and hepatitis C (HCV) virus are the commonest causes of inflammation of the liver leading to chronic liver disease, cirrhosis, hepatocellular carcinoma and even fulminant hepatitis. The objective of this retrospective study was to determine the prevalence of infections with HBV and HCV among patients with chronic hepatitis who visited Bereka Medical Center, southeast Ethiopia.MethodsInstitution based retrospective study design was employed. HBV and HCV test records of all patients with chronic hepatitis who visited Bereka Medical Center from Nov. 2012 to Nov. 2013. A total of 578 (358 for HBV and 220 for HCV) patients with chronic hepatitis screened and the results of all patients were included. All sera were screened using commercially available rapid test kits. Test results were shown in percent and prevalence rates.ResultsThe overall prevalence of HBV and HCV among chronic hepatitis patients were 22.3% and 3.6% respectively. Prevalence of HBV and HCV among males from the total HBV and HCV screened was 52/358 (14.5%) and 6/220 (2.7%) respectively. 64/80 (80%) of HBV sero-positives were found in between 16 to 45 years of age. Of those 64 HBV sero-positive patients, 42/64 (65.6%) were found 16–30 age interval. Furthermore, of those HCV infected, 6/8 (75%) of them fall under 16–30 years of age. 6/8 (75%) of HCV infected patients were males.ConclusionThe present study has shown that HBV was highly prevalent among patients who visited the clinic. Males were more susceptible than female patients. 3.6% HCV prevalence was also high. Mass immunization of HBV is recommended to halt HBV infection.

Seroprevalence of transfusion transmitted infection among blood donors at Jijiga blood bank, Eastern Ethiopia: retrospective 4 years study

“…However our current finding is lower when compared to study done on donors at Felege Hiwot referral hospital 25 % [ 17 ] Buseri et al Nigeria 18.6 % [ 27 ], Taye et al 22.3 % [ 28 ], Bereka Medical center, Southeast Ethiopia.…”

“…From our study, the prevalence rate of HCV was 0.4 %, this is low when compared with 3.1 % in Sudan [ 15 ], Tessema et al 0.7 % [ 7 ], Baye et al 1.7 % [ 10 ], Dessie et al 13.3 % [ 17 ], Wasfi and Sadek among Egyptian donors (3.5 %) [ 6 ], Yohannes Zenebe et al 0.6 % [ 29 ] among pregnant women, 0.9 % prevalence among population and 1.3 % among adults over 15 years old [ 30 ] 0.8 % [ 25 ], Anagaw et al 1 % among medical waste handlers [ 22 ], Bekele Sharew et al 0.61 % [ 21 ], and Taye et al 3.6 % [ 28 ].…”

Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

“…The meta-regression plots for the mean age group and study years were presented in Additional file 4. Similarly, many studies in symptomatic liver disease patients reported HBsAg detection ranging from 9.9 to 35.8% [44–51] with a median prevalence of 21.2% (IQR = 13.4–33.6) (Table 2). The meta-analysis estimate among these patients also showed 20.0% (95%CI: 15.0–26.1) (Additional file 5).…”

“…A similar variation was also reported, among other groups, such as VCT clients [10–12], diabetic patients [58], antenatal care (ANC) [39] and medical waste handlers [32] (Table 4). Likewise, the magnitude of anti-HCV antibody from chronic liver disease patients showed a variable prevalence rate over time with high (37.8%) in 1995 [49] and low (2.7%) in 2014 [51] (Table 4). For the HCV meta-analysis, 24 (75.0%) studies were eligible and selected from the total of 32 studies (Additional file 2).…”

How Intern Doctors Deal with Hepatitis B in Riyadh and Eastern Saudi Arabia

“…Viral hepatitis is an inflammation of the liver that leads to chronic liver disease, liver cirrhosis, and hepatocellular carcinoma and finally, may cause fulminant hepatitis. Hepatitis B is one of the most common viral hepatitis in addition to hepatitis C [1] . Hepatitis B is one of the popular health problems and is considered as a major global infectious hazard.…”