Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

An, Elzouki; Mn, Smeo; Sammud, Mohamed; Elahmer, Omer; M, Daw; Furarah, Abdul Rahaman; Abudher, Abdalhafid; Mk, Mohamed

doi:10.26719/2013.19.7.589

Cited by 26 publications

(35 citation statements)

References 30 publications

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“…The strengths of the present study include the fact that it involved multiple centers, which allowed us to identify the seroprevalence of HBV and HCV, the working period, and the different occupational risks of acquiring infection in HCWs in five different sites in eastern Libya. The lower prevalence of HBsAg (1.8%) was similar to data from a national population-based sero-epidemiological survey that found that the overall prevalence of HBV was 2.2% [6]. Two previous local studies carried out in Libya have found that 31% and 14.8% of HCWs in Tripoli and Benghazi, respectively, were infected [15,16], and the low prevalence among HCWs in the present study might be explained by their awareness of the routes of HBV transmission, the implementation of infection control measures and a free vaccination program.…”

Section: Occupationsupporting

confidence: 85%

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Hepatitis B and C status among health care workers in the five main hospitals in eastern Libya

Elzouki

Elgamay²,

Zorgani

et al. 2014

Journal of Infection and Public Health

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The aim of the present study was to determine the frequency of hepatitis B and C transmission to health care workers (HCWs) in five major hospitals in eastern Libya and to analyze how the risk of these infections are affected by the type of occupation, hospital work place and working period. From July 2008 to June 2009, 601 HCWs (mean age: 32.90 ± 8.85 years) were tested for HBV and HCV markers using ELISA techniques. Polymerase chain reaction (PCR) was performed on all positive samples of HBsAg and Anti-HCV antibody to determine the level of HBV-DNA and HCV-RNA viremia, respectively. The overall frequency of HBsAg positivity was 1.8%. Anti-HBc, HBeAg and Anti-HBe antibodies were found in 8.5%, 0.7% and 8.0% of samples, respectively. The HBV-DNA level was positive in 55% of all HBsAg-positive samples. Approximately half of the HCWs (51.4%) were Anti-HBs antibody positive. The overall positivity rate of Anti-HCV antibodies was 2.0%, and HCV-RNA was positive in 33.3% of these samples. Overall, 52% of HCWs reported receiving full vaccination doses (three doses) against HBV infection. Among them, anti-HBs positivity was approximately 98.0%. 3.9% of those who never received any HBV vaccination dose were HBsAg positive, compared to 1.3% HBsAg positive in those HCWs who had received one or two doses of hepatitis B vaccine (p=0.01 for all comparisons). Nurses and nurse-aides had the highest rates of both HBsAg and Anti-HCV among the studied HCWs (HBsAg: 2.1% and 3.2%; Anti-HCV: 3.2% and 4.9%, respectively). It is noteworthy that doctors also had a relatively high prevalence rate of Anti-HCV (2.2%). Obstetric wards, isolation room, dialysis units and dentist work places had higher frequencies of HBV. HCV was found to be higher in the medical and surgical wards (the prevalence varied between 3% and 5.6%). There was no significant difference between HBsAg status and the work period of HCWs. In conclusion, universal precautions should be applied for the care of all patients by all HCWs. Further, HBV vaccines should be more readily available for Libyan HCWs by reinforcing current vaccination programs.

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Section: Occupationsupporting

confidence: 85%

“…A majority of countries in the Middle East show an intermediate or high endemicity of HBV infection, which clearly poses a serious public health problem in the region [5]. The prevalence of HBV and HCV in Libya has been recently reported in a large general population-based study to be 2.2% for HBsAg and 1.8% for Anti-HCV antibodies [6].…”

Section: Introductionmentioning

confidence: 99%

Hepatitis B and C status among health care workers in the five main hospitals in eastern Libya

Elzouki

Elgamay²,

Zorgani

et al. 2014

Journal of Infection and Public Health

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“…However, 24% of donors didn't have either B hepatitis or C hepatitis. Elzouki has found among the blood donors of Libya a prevalence of the antigen of the hepatitis B and anti-hepatitis C antibodies respectively of 2.2% and 1.3% [9]. Patients with immunosuppressive status with respect to the hepatitis C virus have been met [10].…”

Section: Discussionmentioning

confidence: 99%

Investigation of Hepatitis Functioning through Bilurbin at Blood Donors with HBV and HCV Positive

Ndaya¹,

Kamb²,

Kalenga³

et al. 2017

OALib

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The analysis of the liver functioning through bilurbin dosage has been up on fifty blood donors. The reactive bandages have been used to seek bilurbines in the urines of those patients considered as carriers with HBV and HCV. After analysis, this descriptive study has shown that out of 31 cases found at men more than 25 years old, 27 cases whose livers don't function present a hyper degree of bilurbine when there is hepatitis. The doorstep of 3.9 μmol/L hold 65.2% of hepatitis B and hepatitis C. Whereas at the doorstep of 1.5 μmol/L and 7.8 μmol/L, the HBV has got respectively 8.7% and 26.1% of cases; and HCV has also got 33.3% and 26.7% of cases.

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“…These findings were found to be comparable with that of 76.2%:23.4% of Rajesh N Gacche et al 14 and 72.4%:27.6% of A.N.Elzouki et al study group. 15 …”

Section: Literacymentioning

confidence: 99%

SEROPREVALENCE OF HSV, HBsAg & HCV IN STD CLINIC ATTENDEES OF A TERTIARY CARE STATE HEADQUARTERS HOSPITAL

Godha¹,

S²,

Kumari³

et al. 2017

jemds

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BACKGROUNDSexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed worldwide over unprotected sex. The unprotected sexual activity is contributing for transmission of symptomatic and asymptomatic STIs such as HIV, HBsAg and HCV.The aim is to study seroprevalence of HBsAg, HSV & anti-HCV antibodies in STD clinic attendees of Osmania Medical College/ Osmania General Hospital, Hyderabad. MATERIALS AND METHODSIt is a descriptive study (observational study) conducted from January 2015 -December 2015 at STD Clinic OPD. A total of 3,583 patients who attended the STD Clinic during the above period were studied and patients having direct or indirect risk factors were serotested for the 3 viral infections after inclusion and exclusion criteria with informed consent. A 5 mL of venous blood is collected and the separated serum is tested for HSV 1&2, HBsAg and Anti-HCV antibodies by using ELISA kits. It is ensured that the test kits used have >95% sensitivity and specificity. Settings & Design-All eligible patients attending STD Clinic, Dept. of DVL, Osmania Medical College/Osmania General Hospital, Hyderabad were included in the study after inclusion and exclusion criteria with informed consent. A consecutive sampling methodology with zero intervals is followed. A percentage analysis method is used to derive the conclusions. RESULTSA total of 473 cases are found to be seropositives out of the 3,583 STD clinic attendees for either of 3 STIs showing a seroprevalence of 13.20%, in which male seroprevalence is 13.56% (258 cases) and female seroprevalence is 12.80% (215 cases).In the studied population of 3583, 412 cases were seropositives for HSV Antibodies with seroprevalence of 11.5%, 39 were HBsAg Antibodies positive with seroprevalence of 1.09% and 22 cases were positive for HCV antibodies with seroprevalence of 0.61%. The seropositivity in males and females respectively for HSV is 11.56% and 11.43%; for HBsAg is 1.26% and 0.89%; for HCV is 0.74% and 0.48%. The illiterates (376 of 473=79.49%) and people of low socioeconomic status (371 of 473=78%) are more affected. While 234 of 258 men are having either Premarital, Extramarital or combination accounting to 90.70%, 176 of 215 (81.86%) women are confined to marital sex. CONCLUSIONThe awareness on STIs needs to be well informed before the start of the sexual activity by incorporating the STI/RTI education in school and college curriculum, through IEC activities like mass media campaigns, print & electronic media, by using local cultural festivals, gatherings and through marriage institutions. The at-risk populations such as Sex workers, MSM & IDUs should be covered through specific targeted interventions by utilising NGOs, local bodies and associations.

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Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

Cited by 26 publications

References 30 publications

Hepatitis B and C status among health care workers in the five main hospitals in eastern Libya

Hepatitis B and C status among health care workers in the five main hospitals in eastern Libya

Investigation of Hepatitis Functioning through Bilurbin at Blood Donors with HBV and HCV Positive

SEROPREVALENCE OF HSV, HBsAg & HCV IN STD CLINIC ATTENDEES OF A TERTIARY CARE STATE HEADQUARTERS HOSPITAL

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