2022
DOI: 10.21804/25-1-5045
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Prevalence of hepatitis B and vaccination response in patients with end-stage kidney disease on dialysis at a tertiary centre in the Eastern Cape province of South Africa

Abstract: Introduction: Hepatitis B virus (HBV) infection remains a concern in dialysis populations where vaccination has been less successful than in the general population. Possible reasons for poor response to vaccination in this population include malnutrition, age, uraemia, dialysis vintage, human immunodeficiency virus (HIV) infection and the generalized immunosuppressive state of patients with chronic kidney disease (CKD).Methods: This retrospective point prevalent cohort study evaluated the prevalence of HBV inf… Show more

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“…Numerous research studies have highlighted the demanding situations faced by hemodialysis patients, consisting of immune disorders and impaired vaccine responses, warranting complete research into the hepatitis B vaccination fame (Raina et al, 2022). This observation, performed at Miangul Abdul Haq Jahanzeb Kidney Hospital in Swat, contributes to the developing body of information by delving into the immunization landscape among hemodialysis sufferers, with a particular cognizance on validating the effectiveness of the 20 microgram hepatitis B vaccine (Hussein et al, 2021;Mtingi-Nkonzombi et al, 2022). Understanding the vaccination status of these sufferers is critical for numerous reasons.…”
Section: Introductionmentioning
confidence: 98%
“…Numerous research studies have highlighted the demanding situations faced by hemodialysis patients, consisting of immune disorders and impaired vaccine responses, warranting complete research into the hepatitis B vaccination fame (Raina et al, 2022). This observation, performed at Miangul Abdul Haq Jahanzeb Kidney Hospital in Swat, contributes to the developing body of information by delving into the immunization landscape among hemodialysis sufferers, with a particular cognizance on validating the effectiveness of the 20 microgram hepatitis B vaccine (Hussein et al, 2021;Mtingi-Nkonzombi et al, 2022). Understanding the vaccination status of these sufferers is critical for numerous reasons.…”
Section: Introductionmentioning
confidence: 98%