Prevalence of Hepatitis B and C among HIV Infected Pregnant Women Attending Care and Treatment at National Institute for Pharmaceutical Research and Development (NIPRD), Abuja, Nigeria

Abstract

Introduction: Viral Hepatitis and Human Immunodeficiency Virus (HIV) are most common top ranking leading causes of infectious diseases and deaths worldwide. If these infections, remain unidentified and untreated among HIV infected pregnant women, children born to these pregnant women are at high risk of these viral hepatitis infections.
 Aims: The aim of the study was to determine the sero-prevalence of HBV and HCV among HIV infected pregnant women in Abuja, Nigeria.
 Methodology: A cross sectional study among 330 HIV infected pregnant women commencing antiretroviral therapy (ART) at National Institute for Pharmaceutical Research and Development (NIPRD), Abuja, Nigeria were studied. The women were screened for the presence of HBV and HCV antibodies. A pre-tested questionnaire was used to obtain socio-demographic data prior to recruitment/enrollment. Data were analyzed using statistical product and service solutions (SPSS) (version 20.0).
 Results: Out of the 330 HIV infected pregnant women, 90 (27.3%) were HBV positive, while 5 (1.5%) were HCV positive (p = 0.42). The highest prevalence was observed among the age group of 20 – 29. However, none of the patients tested positive for both HBV and HCV.
 Conclusion: The findings of this study indicated that infection with viral hepatitis is common and of public health concern. Therefore, concerted efforts should be put in place to mitigate the epidemics.

A Systematic Review and Meta-Analysis of the Prevalence of Triplex Infections (Combined Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus) among Pregnant Women in Nigeria

“…In addition, the majority of studies (five out of eight; 62.5%) involved pregnant women in the HIV-positive obstetric population [ 16 , 17 , 19 – 21 ], while three studies (three out of eight; 37.5%) used pregnant women from the general obstetrics population to survey for the prevalence of HIV-HBV-HCV triplex coinfection among ANC attendees [ 18 , 22 , 23 ].…”

“…Sixteen citations were chosen by the reviewers for full-text analysis after titles and abstracts were scrutinized. According to our selection criteria [9,[16][17][18][19][20][21][22][23], nine research were qualified (see Figure 1). Ultimately, eight of nine compatible citations [16][17][18][19][20][21][22][23] were included (Table 1).…”

“…According to our selection criteria [9,[16][17][18][19][20][21][22][23], nine research were qualified (see Figure 1). Ultimately, eight of nine compatible citations [16][17][18][19][20][21][22][23] were included (Table 1). One of the nine qualifying studies was an ongoing one, thus it was excluded [9].…”

“…The eight included studies' [16][17][18][19][20][21][22][23] primary characteristics are also shown in Table 1. Only one study, 1/8 (12.5%), was a longitudinal cohort study, while the majority of the studies were cross-sectional 4/8 (50.0%) [17,[21][22][23] or retrospective cross-sectional studies 3/8 (37.5%) [16,18,20].…”

“…The eight included studies' [16][17][18][19][20][21][22][23] primary characteristics are also shown in Table 1. Only one study, 1/8 (12.5%), was a longitudinal cohort study, while the majority of the studies were cross-sectional 4/8 (50.0%) [17,[21][22][23] or retrospective cross-sectional studies 3/8 (37.5%) [16,18,20]. One study (1/8; 12.5%) was published between 2001 and 2010 [16], while the majority of the studies in our metaanalysis (7/8; 87.5%) were published between 2011and 2021 [18][19][20][21][22][23].…”