Prevalence of hepatitis B and C viruses infection among military personnel at Bahir Dar Armed Forces General Hospital, Ethiopia

Birku, Tigist; Gelaw, Baye; Moges, Feleke; Assefa, Abate

doi:10.1186/s13104-015-1719-2

Cited by 25 publications

(30 citation statements)

References 24 publications

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“…In this study co-infection between HBV and HCV infection serologic markers was 0.3% among the general population. This is in contrast to some studies from Ethiopia where no serologic markers for HBV and HCV co-infection was reported [33-35], indicating that co-infection between HBV and HCV may not be uncommon in the areas where both HBV and HCV are endemic. Our finding is supported by findings from many other studies conducted elsewhere which reported dual infection of HBV and HCV: 0.7% in Nigeria among prison inmates [36]; 5.9% and 2.0% in India among patients with chronic liver disease [37] and hemodialysis patients [32] respectively and 7.7% in Mongolia among patients with chronic liver disease [38].…”

Section: Discussioncontrasting

confidence: 98%

Community-based Sero-prevalence of Hepatitis B and C Infections in South Omo Zone, Southern Ethiopia

Woldegiorgis

Erku

Medhin

et al. 2019

Preprint

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16Background: Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) are the leading causes of 17 liver-related morbidity and mortality throughout the world. The magnitude of HBV and HCV 18 infections in Ethiopia has not been well studied at community level. This study aimed at 19 investigating the sero-prevalence and associated risk factors of HBV and HCV among HBV 20 unvaccinated community members in South Omo Zone, Southern Ethiopia. 21 Methods: A community-based cross-sectional study was conducted in three districts from March 22 to May 2018. Structured questionnaire was used to collect relevant clinical and socio-23 demographic data. Three milliliter of blood sample was collected from each study participant and 24 screened for HBV and HCV using one step hepatitis B surface antigen (HBsAg) test strip and one 25 step HCV test strip, respectively. Samples found positive for HBsAg were further tested using 26 immunoassay of Alere Determine TM HBsAg (Alere Inc., USA). Data was analyzed using SPSS 27 version 25.0. 28 Results: A total of 625 (51.4% males, age 6-80 years, mean age ± SD = 30.83 ± 13.51 years) 29 individuals participated in the study. The sero-prevalence for HBV infection was 8.0% as 30 detected using one step HBsAg test strip, while it was 7.2% using Alere Determine TM HBsAg 31 test. The sero-prevalence for HCV infection was 1.9%. Two (0.3%) of the participants were 32 seropositive for both HBV and HCV infections. High sero-prevalence for HBV infection was 33 associated with weakness and fatigue (AOR = 5.20; 95% CI: 1.58, 17.15), while high sero-34 prevalence of HCV infection was associated with age group between 46 and 65 years (AOR = 35 13.02; 95% CI: 1.11, 152.41).36 Conclusion: this study revealed higher-intermediate endemicity level of HBV infection and low 37 to intermediate endemicity level of HCV infection in the study area. Clinical symptoms like 38 weakness and fatigue were found to be indictors for HBV infection, while individuals in the age 39 group between 46 and 65 years were at higher risk for HCV infection. Provision of community-40 based health education, vaccination, mass screening and providing treatment would have utmost 41 importance in reducing the transmission of these diseases in the present study area. 42 2 43 E viruses. Among these, hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most 48 common causes of viral hepatitis [2]. 49 Both HBV and HCV can be transmitted through sexual, blood or vertically from mother-to-child 50 [3]. Thus, individuals who require blood transfusion, those who have multiple sexual partners 51 and infants born to HBV or HCV infected mothers are at a high-risk for acquiring HBV or 52 HCV infection [4]. Both viruses can cause acute and chronic infection of the liver [5, 6]. Chronic 53 HBV and HCV infections are the leading causes of liver-related morbidity and mortality [7, 8]. 54 Between 15% and 40% of chronically infected individuals can develop serious liver disease and 55 transmit the viruses to others [9, 10]. Globally, about 257 m...

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Section: Discussioncontrasting

confidence: 98%

Community-based Sero-prevalence of Hepatitis B and C Infections in South Omo Zone, Southern Ethiopia

Woldegiorgis

Erku

Medhin

et al. 2019

Preprint

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“…The least infected group (3.1%) were people aged 51 years and above. This finding is in agreement with the report of Bezabeh et al [28] and Birku et al [30] in Ethiopia. According to previous epidemiological studies, there has been a link between age and the prevalence of HBsAg.…”

Section: Discussionsupporting

confidence: 94%

Prevalence of HBsAg and HBV Serotypes Using Antigen Detection and PCR Methods among Human Immunodeficiency Virus Patients Accessing Healthcare in a Tertiary Healthcare Facility in Central Nigeria

Abimiku

Victor

Pennap

et al. 2017

JAMB

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Hepatitis B virus (HBV) co-infection with human immunodeficiency virus is a major public health problem especially in developing countries. In a descriptive study, the prevalence of HBsAg and HBV serotypes using antigen detection and PCR methods were evaluated among HIV patients accessing healthcare in a Tertiary Healthcare Facility in Central Nigeria. After ethical clearance, blood samples were aseptically collected between January to April 2016 from 547 subjects who gave informed consent and completed self-administered questionnaire. Blood samples were analyzed using HBsAg screening kit (ACON Laboratories Inc, USA) and Nested PCR approach. The Chi-square statistical test was performed to identify possible risk factors associated with the viral seropositivity. Overall, 53 (9.7%) had IgG antibodies against HBV. A higher prevalence of Short Research Article

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“…The prevalence of HCV infection has been estimated about 3% in the world (13). There are approximately 170 million people with chronic hepatitis C virus (HCV) infection (14,15). HCV infection is a major cause of liver cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver disease (16,17).…”

Section: Contextmentioning

confidence: 99%

Is Tattooing a Risk Factor for Hepatitis C Transmission?: An Updated Systematic Review and Meta-Analysis

et al. 2017

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The aim of this systematic review was to assess the association of tattooing with the risk of hepatitis C infection. Evidence Acquisition: A systematic search was performed in Medline, Web of Science, Scopus, Google scholar, EMBASE, CINAHL, and PubMed up to May 2017. To analyze the data using random effect, odds ratio (OR) with 95% confidence interval (CI) was calculated for each study. We also determined publication bias and heterogeneity among the 162 extracted articles. Results: We included 163 relevant studies out of the 2353 extracted studies into the meta-analysis process. When all studies were included in the meta-analysis, the association between tattooing and risk of hepatitis C transmission was strongly significant (pooled OR = 2.79, 95% CI: 2.46-3.18). Subgroup analysis showed the strongest association between tattooing and the risk of hepatitis C among samples from blood donors groups (OR = 4.09, 95% CI: 2.80-5.98). Conclusions: This meta-analysis study revealed that tattooing is strongly associated with transmission of hepatitis C in all subgroups. Relevant education is recommended for young adults who are more likely to get tattoos as well as for prison inmates who have demonstrated high prevalence of hepatitis C infection. In addition, it seems necessary to implement prevention programs and enforce guidelines for safer tattooing practices in tattoo parlors in order to prevent hepatitis C transmission.

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Prevalence of hepatitis B and C viruses infection among military personnel at Bahir Dar Armed Forces General Hospital, Ethiopia

Cited by 25 publications

References 24 publications

Community-based Sero-prevalence of Hepatitis B and C Infections in South Omo Zone, Southern Ethiopia

Community-based Sero-prevalence of Hepatitis B and C Infections in South Omo Zone, Southern Ethiopia

Prevalence of HBsAg and HBV Serotypes Using Antigen Detection and PCR Methods among Human Immunodeficiency Virus Patients Accessing Healthcare in a Tertiary Healthcare Facility in Central Nigeria

Is Tattooing a Risk Factor for Hepatitis C Transmission?: An Updated Systematic Review and Meta-Analysis

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