Prevalence of Hepatitis B Antigen

Vissoulis, C.; Papaevangelou, G.

doi:10.1093/infdis/128.6.807

Cited by 3 publications

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“…The age curve of HBsAg prevalence has a pattern similar to that of other populations (Vissoulis & Papaevangelou, 1973 (Gerety, Hoofnagle, Markenson & Barker, 1974).…”

Section: Discussionsupporting

confidence: 71%

Seroepidemiological study of HBV infections in Athens, Greece

Papaevangelou

Kyriakidou

Vissoulis

et al. 1976

J. Hyg.

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SUMMARYA seroepidemiological survey of a sample -roughly representative by age and sex -of 2744 persons of the Greater Athens area revealed that hepatitis B virus (HBV) infections are highly endemic in Greece. Hepatitis B surface antigen (HBsAg) was detected in 72 (2.6 %) of them. The subtype was identified in 70 of the 72 carriers, and 69 were ay; the other was ad. Determinant w was present in all 61 that were capable of being typed further, and a23y(w) was twice as common as a1ly(w). Antibody to HBsAg (anti-HBs) was found in 514 (18-7 %) persons. The prevalence of the HBsAg rose rapidly with age, reaching peak values (5.3 %) at 20-29 years, while anti-HBs reached its highest value (42.1 %) in older age groups (50-59 years). The frequency of HBsAg was significantly higher in males (3.4 %) than in females (1-5 %). The percentage of infected persons who become chronic HBsAg carriers (12.3 %) was found higher than in other developed populations. It was also found higher in children (25 %) than in adults (5.5 %) and in males (14.6 %) than in females (8.1 %). These data indicate that HBV infection in early life is a major risk factor in the development of HBsAg carriers and support the hypothesis that males are more likely to become HBsAg carriers than females.

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“…The age curve of HBsAg prevalence has a pattern similar to that of other populations (Vissoulis & Papaevangelou, 1973 (Gerety, Hoofnagle, Markenson & Barker, 1974).…”

Section: Discussionsupporting

confidence: 71%

Seroepidemiological study of HBV infections in Athens, Greece

Papaevangelou

Kyriakidou

Vissoulis

et al. 1976

J. Hyg.

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“…Ή νόσος δύναται νά μεταδοθή καθέτως εις τό έμβρυον, όταν ή μήτηρ προσβληθή ύπό οξείας ήπατίτιδος Β κατά τό 2ον ή 3ον τρίμηνον της κυήσεως (Παπαευαγγέλου 1972b, Papaevangelou 1973, Schweitzer et al, 1973a. Παρά τό ότι έχει διαπιστωθεί (Papaevangelou et al, 1974b), ή δίοδος του αντιγόνου διά τοϋ πλακοϋντος, ή κάθετος μόλυνσις τοϋ εμβρύου δέν είναι τόσον συχνή άπό μητέρας α'ι όποΐαι είναι υγιείς φορείς του ίοΰ Β.…”

Section: κάθετος μετάδοσιςunclassified

“…Όσον αφορά τήν ήλικίαν τών ανωτέρω ασθενών, τό μεγαλύτερον ποσοστόν έκ τών νοσηλευθέντων, τόσον τών θετικών όσον καί τών αρνητικών διά HBsAg ασθενών, ανήκει εις τήν ομάδα τών ηλικιών 20 -29 ετών. ' Η ομάς αϋτη αντιπροσωπεύει καί τήν αίχμήν της νοσηρότητος τοϋ γενικού πληθυσμού έξ ίογενοϋς ήπατίτιδος (Vissoulis and Papaevangelou 1973). Άξιοσημείωτον είναι τό γεγονός ότι εις τους θετικούς διά HBsAg ασθενείς, ή δευτέρα κατά σειράν συχνότητος ομάς ηλικιών είναι ή τών 30 -39 ετών, ένώ εις τους αρνητικούς διά HBsAg ασθενείς ή ομάς τών ηλικιών 15-19 ετών.…”

Section: δοκιμασία προσροφήσεωςunclassified

Μελετη Χαρακτηριστικων Ασθενων Νοσηλευομενων Δια Οξειαν Ηπατιτιδα Εις Το Νοσοκομειον Λοιμωδων Νοσων Αθηνων

Πανουτσου¹

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Η παρούσα διατριβή έγένετο ύπό τήν παρακολούθησιν του καθηγη τού της "Εδρας "Υγιεινής και 'Επιδημιολογίας τού Πανεπιστημίου 'Αθη νών κ. Δ. Τριχοπούλου και ύπό τήν έποπτείαν καί συνεργασίαν τού Διευθυντού τού Ν.Ε.Ε.Σ., καθηγητού της 'Υγειονομικής Σχολής Αθηνών, κ. Γ. Παπαευαγγέλου.

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Hepatitis B Surface Antigen in Blood Donors: Further Observations

Szmuness¹,

Hirsch²,

Prince³

et al. 1975

Journal of Infectious Diseases

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A survey of 128,000 volunteer blood donors from the Greater New York metropolitan area revealed that first-time male donors were positive for hepatitis B surface antigen (HBsAg) 2.5 times more frequently than were first-time female donors; Negroes and Mongols were positive four to 20 times more frequently than Caucasians. The ratio of ad to ay seemed to be higher in non-Caucasian antigen carriers than in Caucasian carriers. Among both Caucasians and non-Caucasians the rate of positivity declined after the age of 50. An excess prevalence of HBsAg was observed in donors with the lowest level of education and in those with the highest level. HBsAg was detectable nine times less frequently among repeat donors than among first-time donors (0.2 vs.1.90 per 1,000). Detection of HBsAg was unrelated to ABO-Rh blood groups. Several mechanisms for these wide variations of antigen detection are possible.

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Prevalence of Hepatitis B Antigen

Cited by 3 publications

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Seroepidemiological study of HBV infections in Athens, Greece

Seroepidemiological study of HBV infections in Athens, Greece

Μελετη Χαρακτηριστικων Ασθενων Νοσηλευομενων Δια Οξειαν Ηπατιτιδα Εις Το Νοσοκομειον Λοιμωδων Νοσων Αθηνων

Hepatitis B Surface Antigen in Blood Donors: Further Observations

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