Prevalence of hepatitis C infection among children with  -thalassaemia major in Mid Delta, Egypt: a single centre study

Abstract

HCV infection is highly prevalent in children with β-TM in Egypt despite strict pre-transfusion blood testing. This should arouse the attention for environmental and community acquired factors. Quality management to insure infection control in minor operative procedures and adding more sensitive tests for blood screening are recommended.

Seropositivity of Hepatitis B and C among Syrian Multitransfused Patients

“…This coincides with previous reports,4,12 but contradicts others 3,14,16–18. Gender does not seem a risk factor for acquiring TTI, but was unexpectedly associated with HCV seropositivity in our study; this finding was also reported elsewhere 19.…”

“…Likewise, anti-HCV seropositivity in our patients (11.32%) was lower than those reported among multitransfused patients in Jordan (40%),2 Egypt (45% to 76%),4,15 Iran (44.7%),16 India (16% to 26%)5 and Pakistan (51.3%),17 which is reflected by the relatively lower prevalence (0.95%) of HCV seropositivity among Syrian blood donors 8…”

“…Albeit an essential lifesaving intervention, blood transfusion carries the risk of transfusion-transmitted infections (TTIs), such as hepatitis B and C,2 which compose a major challenge to the public health worldwide 3. In general, screening blood donors with sensitive methods has reduced the incidence of TTIs 4. However, the risk of TTIs is still present when infectious blood is donated within the window period,5 especially among multi-transfused patients because of frequent exposure to blood products 4…”

“…In general, screening blood donors with sensitive methods has reduced the incidence of TTIs 4. However, the risk of TTIs is still present when infectious blood is donated within the window period,5 especially among multi-transfused patients because of frequent exposure to blood products 4…”

A comprehensive hepatitis C virus risk factors meta‐analysis (1989–2013); Do they differ in Egypt?

“…Sharing razors (83,84), sharp objects (nail clippers, manicure cutters, scissors) (83), tooth brush (85), non-sharp objects (shower scrapper, towels, combs) (48,(86)(87)(88), and some folk medical practices including cupping/ventosed bloodletting (known in the Arab world as hijama) (37,(89)(90)(91), circumcision and ritual clitorodectomy (36,41,69,76,92) were studied as risk factors for HCV infection only in the late 1990s. Similarly, the role of barber was only addressed during the last decade.…”