Prevalence of hepatitis C virus seroconversion among hemodialysis patients in Egypt

Sarhan, Iman Ibrahim; Kamel, Cherry Reda

doi:10.1097/01.elx.0000463167.48017.41

Cited by 10 publications

(8 citation statements)

References 21 publications

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“…In addition, it agreed with the study of Sarhan and Kamel [8] in Cairo, Egypt, which reported that the prevalence of HCV antibody at the start of dialysis was 45.2% and the incidence rate of seroconversion was 10.7%. Their study included 987 patients who attended 22 HD centers.…”

Section: Discussionsupporting

confidence: 90%

Prevalence and seroconversion of hepatitis C among hemodialysis patients in Assiut governorate, Egypt

et al. 2020

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Background: The prevalence of hepatitis C (HCV) infection among the patients on hemodialysis (HD) varies from country to country and from one center to another in the same country. Despite the existence of guidelines for the infection control program, Egypt is one of the countries with high HCV prevalence. In Egypt, the prevalence of HCV among hemodialysis patients in 2015 survey was 50.7%. This study aimed to evaluate the prevalence and seroconversion rate of hepatitis C infection and the risk factors for seroconversion in our community hemodialysis units. Results: The prevalence of HCV was 34.8% among hemodialysis patients. The seroconversion rate was 13.2%. The positive history of blood transfusion and the frequency of blood transfusion, in addition to the handling by medical staff to equipment and blood products and the number of inserted temporary dialysis catheters, were found to be significant risk factors for seroconversion. Conclusion: We concluded that there is a high prevalence of HCV infection in the dialysis units of our community and a relatively high seroconversion rate among hemodialysis patients.

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Section: Discussionsupporting

confidence: 90%

Prevalence and seroconversion of hepatitis C among hemodialysis patients in Assiut governorate, Egypt

et al. 2020

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“…In the current study, gender, blood transfusion, dialysis vintage, renal transplant, body tattooing, surgical and dental procedures were not associated with increased rate of HBV, this observation was inconsistent with those of several studies that related one or more of these potential risk factors to higher rates of HBV infection (5,7,(19)(20)(21), but it was similar to that of a study from lran (16).…”

Section: Discussioncontrasting

confidence: 99%

“…Duration on HD was a statistically significant risk factor for HCV infection in HD population under investigation (P < 0.001), this explained that nosocomial transmission was related to dialysis, since longer duration of dialysis represented a longer period at risk of acquiring an infection. Similar observations are reported by other authors (8,11,(19)(20)(21). In accordance with other studies (8,11,19), HCV infection was more prevalent in patients with a history of previous kidney transplant, which could be attributed to immunosuppressive drugs, making them more liable to acquiring infection.…”

Section: Discussionsupporting

confidence: 92%

“…Although blood transfusion was regarded a risk factor for HCV infection in some studies (11,20), in the current study and several others (8,21) no significant association was observed, which could be the result of effective blood screening methods.…”

Section: Discussioncontrasting

confidence: 71%

“…In the current study results, in agreement with those of others (16,(19)(20)(21), no association was observed between HCV prevalence and gender of the patients; it was inconsistent with those of DOPPS study (8).…”

Section: Discussioncontrasting

confidence: 51%

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Prevalence and Risk Factors of Hepatitis B and C Virus Infections Among Patients Undergoing Hemodialysis in Kurdistan, Iraq

Sinjari

Bakr

2018

Hepat Mon

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Background and Objectives: Hepatitis B and C viral (HBV, HCV) infections are major the health problems worldwide. Patients undergoing hemodialysis (HD) are more vulnerable to acquire such infections than the general population. The current study aimed at assessing the prevalence and risk factors of HBV and HCV infections among patients undergoing hemodialysis in Kurdistan, Iraq. Methods: The current cross sectional study was carried out at five governmental dialysis units in Kurdistan, Iraq; most of the current study patients were recruited from 10 August 2015 to 11 February 2016. All the participants were clinically evaluated and detailed history of blood transfusion, duration of HD, and all the other parameters were also noted. Hepatitis B surface antigens (HBsAgs) and anti-HCV antibodies (anti-HCV Ab) were measured and seropositive HCV samples were subjected to polymerase chain reaction (PCR) for confirmation. Data regarding the serological status of such patients and potential risk factors were collected and analyzed. Results: A total of 510 patients undergoing HD were enrolled in the study. The overall prevalence of HBV, HCV, and coinfection in the studied subjects was 1.8%, 9.2%, and 0.2%, respectively. HBV and HCV infections were independently associated with age and history of HD (P = 0.005). HBV vaccination was a strong protective factor against HBV infection (P = 0.001), but the rate of fully vaccinated patients (77%) was still suboptimal. Other risk factors for HCV infection were the duration of HD, history of kidney transplantation, and history of dental and surgical procedures. Conclusions: The prevalence of HBV and HCV infections in the patients undergoing HD in the centers in Kurdistan was low to moderate. HBV vaccination was an efficient protective measure. The factors associated with viral hepatitis within HD units were highly suggestive for nosocomial transmission. Strict adherence to infection control measures and more effective follow-up procedures may reduce the prevalence of the studied infections.

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Hepatitis C virus in patients on regular hemodialysis in Beni-Suef Governorate, Egypt

Senosy

Shabrawy²

2016

Journal of the Egyptian Public Health Association

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Prevalence of hepatitis C virus seroconversion among hemodialysis patients in Egypt

Cited by 10 publications

References 21 publications

Prevalence and seroconversion of hepatitis C among hemodialysis patients in Assiut governorate, Egypt

Prevalence and seroconversion of hepatitis C among hemodialysis patients in Assiut governorate, Egypt

Prevalence and Risk Factors of Hepatitis B and C Virus Infections Among Patients Undergoing Hemodialysis in Kurdistan, Iraq

Hepatitis C virus in patients on regular hemodialysis in Beni-Suef Governorate, Egypt

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