Prevalence of herpes zoster virus reactivation in patients diagnosed with Bell's palsy

Castro, Rafael Freire de; Crema, Daniela; Neiva, Felipe Costa; Pinto, Roberta Arb Saba Rodrigues; Suzuki, Fábio Akira

doi:10.1017/s0022215121004631

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…The etiology of Bell's palsy remains incompletely understood but is widely believed to be associated with viral infections, such as herpes simplex virus, and immune system abnormalities [13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Development of a clinical diagnostic model for Bell's palsy in patients with facial muscle weakness

Li,

Chen,

Lai

et al. 2024

Biomol Biomed

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Early diagnosis of Bell's palsy is crucial for effective patient management in primary care settings. This study aimed to develop a simplified diagnostic tool to enhance the accuracy of identifying Bell's palsy among patients with facial muscle weakness. Data from 240 patients were analyzed using seven potential clinical evaluation indicators. Two diagnostic benchmarks were established: one based on clinical assessment and the other incorporating magnetic resonance imaging (MRI) findings. A multivariate logistic regression model was developed based on these benchmarks, resulting in the construction of a predictive tool evaluated through latent class models. Both models retained four key clinical indicators: absence of forehead wrinkles, accumulation of food and saliva inside the mouth on the affected side, presence of vesicular rash in the ear or pharynx, and lack of pain or symptoms associated with tick exposure, rash, or joint pain. The first model demonstrated excellent discriminative ability (area under the curve [AUC] = 0.96, 95% confidence interval [CI] 0.94 - 0.99) and calibration (P < 0.001), while the second model also showed good performance (AUC = 0.88, 95% CI 0.83 - 0.92) and calibration (P = 0.005). Bootstrap validation indicated no significant overfitting. The latent class defined by the first model significantly aligned with the clinical diagnosis group, while the second model showed lower consistency.

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Section: Introductionmentioning

confidence: 99%

Development of a clinical diagnostic model for Bell's palsy in patients with facial muscle weakness

Li,

Chen,

Lai

et al. 2024

Biomol Biomed

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show abstract

A case of recurrent left facial neuropathy during pregnancy

Shpak,

Zhelezov,

Vorokhta

2024

INJ

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An analysis of the features of acute facial neuropathy during pregnancy was carried out. The article considers a clinical case of recurrent left facial neuropathy during pregnancy with complete regression of symptoms after therapy. Recurrent Bell’s palsy occurred in a 35-year-old woman during her third pregnancy. In the third trimester of the second pregnancy, she had a mild left-sided prosoparesis (grade 1 on the House-Brackmann scale). The patient received corticosteroid therapy (prednisone orally), gave birth on time, and the paresis completely regressed after treatment. Parity between pregnancies was 2 years. During the current pregnancy, at 37 weeks, the patient developed pronounced left-sided prosoparesis (grade 4 on the House-Brackmann scale). She received betamethasone at a dose of 12 mg per day for 2 days. A week later, after induction of labor with oxytocin, she gave birth to a boy weighing 3,765 g, body length was 51 cm. One-minute Apgar score was 8 points, five-minute Apgar score was 8 points. In the postpartum period, the patient underwent physical therapy and did mimic gymnastics. Magnetic resonance imaging performed after delivery revealed no signs of vasoneural conflict and focal lesions. Complete regression of symptoms was achieved, which is a rather rare clinical outcome in such patients. Recurrent Bell’s palsy usually occurs in pregnant women with comorbid diabetes, obesity, insulin resistance, and hypertension. In this case, there was no pronounced comorbid background. The algorithm used in obstetric practice to prevent fetal distress syndrome with betamethasone administration for 48 hours was applied in our patient. The role of interaction in the format of a multidisciplinary team when managing pregnant women with neurological pathology is analyzed.

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Prevalence of herpes zoster virus reactivation in patients diagnosed with Bell's palsy

Cited by 2 publications

References 19 publications

Development of a clinical diagnostic model for Bell's palsy in patients with facial muscle weakness

Development of a clinical diagnostic model for Bell's palsy in patients with facial muscle weakness

A case of recurrent left facial neuropathy during pregnancy

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