Prevalence of HIV infection among tuberculosis patients in a teaching hospital in south-west Nigeria: A four-year retrospective study

Ranti, Kolade O.; Glory, Atilola O.; Victoria, Babalola T.; Isaac, Komolafe O.

doi:10.1016/j.hivar.2016.11.001

Cited by 5 publications

(9 citation statements)

References 14 publications

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“…Compared with the results of this study Oladeinde et al (2014) and Ranti et al (2016) (Gunda et al, 2018). Similar to the findings of this study, Manjareekaa and Nanda (2013) reported similar TB/HIV co-infection rate of 12.3% in the Central Hospital of South Eastern Railway, India.…”

Section: Discussionsupporting

confidence: 48%

Prevalence of Human Immunodeficiency Virus Infection among Tuberculosis Patients at Infectious Disease Hospital, Kano State, Nigeria

Aminu¹

2020

UJMR

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The epidemic of Human Immunodeficiency Virus (HIV) and the emergence of drug resistant Mycobacterium tuberculosis strains have been recognized as the most important factors contributing to increasing resurgence of tuberculosis (TB). This study was conducted to determine the prevalence of HIV among tuberculosis patients and drug sensitivity pattern of some of the mycobacterial isolates. One hundred and sixty eight (168) sputum samples from tuberculosis patients attending Infectious Diseases Hospital, Kano were collected and processed for the presence of Mycobacteria. Blood samples of the patients were also screened for the presence of HIV. The drug susceptibility test (DST) was performed using the BACTEC Mycobacteria Growth Inhibitory Test (MGIT) M960 technique. Results revealed that out of the 168 patients studied 24 (14.29%) were TB and HIV co-infected and 135 (68.88%) were males while 61 (31.12%) were females (P = 0.001). Majority of the studied cases were of the age groups 15-24 years and 25-34 years (P = 0.001). Ten (58.82%) of the 17 isolates that were subjected to DST against the first-line anti-TB drugs (isoniazid, rifampicin, ethambutol, pyrazinamide) were found to be resistant against the various drugs to which they were tested; out of which 7 (41.17%) exhibited a primary drug resistance pattern, 3 (17.65%) exhibited acquired drug resistance pattern and 2 (11.74%) were multi-drug resistant TB. The highest drug resistance of 23.53% was recorded against isoniazid, followed by rifampicin, ethambutol and pyrazinamide each with a resistance of 17.65%. The study recommends screening of all TB patients for early diagnosis of HIV co-infection as well as conducting DST which will inform prompt management of the infected individuals and designing appropriate treatment schedule for effective TB/HV control as well as preventing transmission of drug resistant TB. Key words: Tuberculosis, Human Immunodeficiency Virus, Infection, Prevalence, Drug Susceptibility.

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Section: Discussionsupporting

confidence: 48%

Prevalence of Human Immunodeficiency Virus Infection among Tuberculosis Patients at Infectious Disease Hospital, Kano State, Nigeria

Aminu¹

2020

UJMR

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“…This result agrees with previous reports on the seroprevalence of HIV among TB patients, which indicated highly variable rates of HIV-TB co-infection worldwide; for instance, in Eastern India, the seroprevalence was 44%; in Sindh, Pakistan 0.29%; and in Cambodia it was 38%. 2,9,11,12,[20][21][22][23] The prevalence of HIV among TB patients in this work was higher than that reported by the World Health Organization in 2018 (2%) and lower than the 2016 report (4.9%). 1,14,15 Compared with other regions, the prevalence of HIV among patients in this study was lower than that reported recently in Ogun State, Nigeria, 11 in which the prevalence of HIV infection was 29.3%, with 34% of these among TB patients in the middle age group (25-49 years).…”

Section: Discussionmentioning

confidence: 72%

“…Furthermore, dissemination of information on the HIV/AIDS epidemic and its impact on TB patients for more systematic surveillance is urgently required, necessitating the development of joint strategies for resources and planning activities for people with HIV and TB co-infection. [11][12][13] Countries such as those in the Sub-Saharan Africa are severely impacted by the HIV/AIDS pandemic and urgently need special consideration in tacking this issue; for instance, a recent study reported that, of the total number of people with HIV worldwide, 6 six of every 10 men, 5 of every 10 women, and 9 of every 10 children live in Sub-Saharan Africa. 11 According to the World Health Organization annual global report in 2016 about the status of TB infection in Sudan, 7% of the TB patients were also positive for HIV, 14 and in 2018 this was estimated to be 3%.…”

Section: Introductionmentioning

confidence: 99%

“…[11][12][13] Countries such as those in the Sub-Saharan Africa are severely impacted by the HIV/AIDS pandemic and urgently need special consideration in tacking this issue; for instance, a recent study reported that, of the total number of people with HIV worldwide, 6 six of every 10 men, 5 of every 10 women, and 9 of every 10 children live in Sub-Saharan Africa. 11 According to the World Health Organization annual global report in 2016 about the status of TB infection in Sudan, 7% of the TB patients were also positive for HIV, 14 and in 2018 this was estimated to be 3%. 15 Despite the fact that the first report on the HIV/AIDS status in Sudan was published in 1986 and that Sudan is an endemic area of TB, very limited data on HIV-TB co-infection are available.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of human immunodeficiency virus among pulmonary tuberculosis patients: A cross‐sectional study

Moglad

Ahmed

AL‐Kareem

et al. 2020

Microbiology and Immunology

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Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is an endemic disease in Sudan, where it has rapidly become the major complication of human immunodeficiency virus (HIV) infection. Thus, this study aimed to determine the prevalence of HIV among TB patients and evaluate the co-infection rate. The association of HIV prevalence with gender, age, and duration of treatment as risk factors was also determined. A descriptive cross-sectional study was performed in

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“…Os resultados corroboram com estudo realizado em um país em desenvolvimento, o qual aponta que a grande maioria dessa coinfecção concentra-se no grupo etário economicamente produtivo (entre 25 a 49 anos). Este fato pode ser justificado devido a uma maior exposição às atividades realizadas nesta fase da vida, como relações sexuais, transfusões de sangue com seringas e agulhas contaminadas e uso de drogas injetáveis (11) .…”

Section: Discussionunclassified

Análise Epidemiológica Da Coinfecção Tuberculose/Hiv

et al. 2018

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RESUMO:Objetivo: analisar o perfil epidemiológico da coinfecção tuberculose e o vírus da imunodeficiência. Método: estudo descritivo, realizado com levantamento na base de dados do Sistema de Informação de Agravos de Notificação no estado do Piauí, no período de 2007 a 2016. A coleta ocorreu por meio de instrumento contendo características sociodemográficas e relacionadas à coinfecção Tuberculose/vírus da imunodeficiência. Realizouse análise descritiva simples. Resultados: A prevalência da coinfecção tuberculose e vírus da imunodeficiência foi de 6,1% pacientes (n=619). Os dados mostram a predominância de indivíduos do sexo masculino (n=467/ 75,4%), adultos com faixa etária entre 20 a 49 anos (n=492/ 79,5%) e pardos (n=457/ 73,8%). A forma clínica da tuberculose mais encontrada foi a pulmonar com n=412 (66,6%) casos. O percentual de cura dos destes pacientes foi de 60,8%. Conclusão: Os resultados apontaram uma alta prevalência dessa coinfecção e uma elevada detecção da infecção do vírus da imunodeficiência em pacientes com tuberculose. DESCRITORES: Tuberculose; HIV; Prevalência; Epidemiologia; Coinfecção. ANÁLISIS EPIDEMIOLÓGICO DE LA COINFECCIÓN TUBERCULOSIS/VIH RESUMEN: Objetivo: analizar el perfil epidemiológico de la coinfección por la tuberculosis y el virus de la inmunodeficiencia. Método: estudio descriptivo con búsqueda en la base de datos del Sistema de Información de Agravios de Notificación en el estado de Piauí, en el período de 2007 a 2016. Los datos fueron recolectados mediante instrumento con características sociodemográficas y relacionadas a la coinfección Tuberculosis/virus de la inmunodeficiencia. Fue aplicado análisis descriptivo simple. Resultados: La prevalencia de la coinfección tuberculosis y virus de la inmunodeficiencia correspondió al 6,1% de los pacientes (n=619). Los datos muestran la predominancia de individuos del sexo masculino (n=467/75,4%), adultos con rango de edad entre 20 y 49 años (n=492/ 79,5%) y pardos (n=457/73,8%). La forma clínica de la tuberculosis más encontrada fue la pulmonar con n=412 (66,6%) casos. El porcentaje de cura de estos pacientes fue del 60,8%. Conclusión: Los resultados indicaron alta prevalencia de esa coinfección y alta detección de la coinfección por el virus de la inmunodeficiencia en pacientes con tuberculosis.

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Prevalence of HIV infection among tuberculosis patients in a teaching hospital in south-west Nigeria: A four-year retrospective study

Cited by 5 publications

References 14 publications

Prevalence of Human Immunodeficiency Virus Infection among Tuberculosis Patients at Infectious Disease Hospital, Kano State, Nigeria

Prevalence of Human Immunodeficiency Virus Infection among Tuberculosis Patients at Infectious Disease Hospital, Kano State, Nigeria

Prevalence of human immunodeficiency virus among pulmonary tuberculosis patients: A cross‐sectional study

Análise Epidemiológica Da Coinfecção Tuberculose/Hiv

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