Prevalence of Human Metapneumovirus Infections in Iran: A Systematic Review and Meta-Analysis

Malekshahi, Somayeh Shatizadeh; Yavarian, Jila; Shafiei‐Jandaghi, Nazanin‐Zahra; Mokhtari‐Azad, Talat; Farahmand, Mohammad

doi:10.1080/15513815.2020.1725939

Cited by 6 publications

(7 citation statements)

References 54 publications

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“…They also found HMPV, HCoV‐NL63, and HRSV by higher prevalence rates, which may be due to high circulation rates of respiratory viruses, especially from 2020–2021 to 2021–2022 during the COVID‐19 pandemic waves. The previous studies in Iran before COVID‐19 pandemic had shown the prevalence rates of HRSV, Flu, and HMPV as 18.0%, 9 10.5%, 10 and 8.9%, respectively 11 …”

Section: Discussionmentioning

confidence: 94%

“…The previous studies in Iran before COVID-19 pandemic had shown the prevalence rates of HRSV, Flu, and HMPV as 18.0%, 9 10.5%, 10 and 8.9%, respectively. 11 During the early months of COVID-19 spread in Iran, coinfection was recorded in 22.3% of death cases, especially for Flu A. 12 Co-infection of Flu A with SARS-CoV-2 at the same time in Wuhan was reported to be 57.3%.…”

Section: Resultsmentioning

confidence: 99%

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The prevalence of 17 common respiratory viruses in patients with respiratory illness but negative for COVID‐19: A cross‐sectional study

Sadeh Tehrani,

Mohammadjafari,

Alizadeh

et al. 2024

Health Science Reports

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Background and AimsSecond to COVID‐19 pandemic, other viral respiratory infections are still important causes of human diseases or co‐infections. Hence, the present study was carried out to investigate the common respiratory viruses in patients with respiratory illness diagnosed negative for severe acute respiratory syndrome coronavirus‐2 in primary screening.MethodsIn a cross‐sectional study, a real‐time PCR was carried out using HiTeq. 17 Viro Respiratory pathogen One Step RT‐PCR Kit (Genova, Bonda Faravar, Bioluence, Tehran, Iran).ResultsA total of 311 individuals (mean age ± SD: 48.2 ± 21.7 years, range: 1–97 years) underwent second PCR. Among these, 161 (51.7%) were female. In total, 55 (17.6%) cases (mean age ± SD: 45.7 ± 18.1 years) were found positive for respiratory viruses panel in the second PCR. The HCoV‐OC43/HKU1 was in 5.4% (17/311), Flu A in 4.5% (14/311), HCoV‐229E/NL63 in 2.8% (9/311), HMPV in 1.9% (6/311), HPiV 1, 2, 3 in 1.2% (4/311), HRSV in 0.9% (3/311), and HAdV in 0.6% (2/311) of the cases studies. Also, co‐infection was detected in 4 samples (1.2%). In addition, sore throat (0.028), headache (p = 0.016), and body pain (p = 0.0001) were statistically the most significant symptoms in studied cases.ConclusionAccording to the findings of our study, respiratory virus infections and co‐infections were 17.6% and 1.2% frequent, respectively. Interestingly, nearly half of our positive cases (47.2%) were identified by coronaviruses (ОС43, Е229, NL63, and HKUI), followed by influenza A virus (25.4%). However, for more comprehensive results, we recommend using greater sample size.

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Section: Discussionmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

The prevalence of 17 common respiratory viruses in patients with respiratory illness but negative for COVID‐19: A cross‐sectional study

Sadeh Tehrani,

Mohammadjafari,

Alizadeh

et al. 2024

Health Science Reports

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“…The main reasons for differences in coinfection frequency across countries and regions might rely on the patients being investigated, geographical and seasonal variability, study period, prevention and control measures implemented, testing methods, and the spectrum of pathogens targeted. According to the results of a recent systematic review and metaanalysis, the prevalence rates of RSV, IFV, and hMPV were estimated to be 18.0% (22), 10.5% (23), and 8.9% (24) in the prepandemic period in Iran. A detailed analysis of coinfecting pathogens (Table 2) showed that all viral coinfections were reported at less than a 5% frequency rate, apart from hMPV in SARS-CoV-2-positive and negative samples.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Detection of Multiple Respiratory Viruses Among SARS-CoV-2-Positive and Negative Patients by Multiplex TaqMan One-Step Real-Time PCR

Veisi¹,

Malekshahi²,

Choobin³

et al. 2022

Jundishapur J Microbiol

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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has clinical manifestations similar to other common respiratory viral infections. There are limited data on the frequency of viral respiratory coinfection among patients infected with SARS-CoV-2 in Iran. Objectives: This cross-sectional study investigated the prevalence of multiple respiratory viruses among SARS-CoV-2-positive and negative patients during the coronavirus disease 2019 (COVID-19) pandemic in Iran. Methods: We included oropharyngeal/nasopharyngeal swab specimens of patients suspected of COVID-19 from December 2020 to March 2021. A reliable multiplex TaqMan one-step real-time PCR method was employed to detect 17 viral respiratory pathogens simultaneously. Descriptive analyses were performed to characterize the specimens concerning age, gender, clinical manifestations, and underlying disease. Results: Multiple respiratory viruses with a frequency of 18.78% were detected in 197 studied patients. Human metapneumovirus was the most prevalent pathogen detected in both SARS-CoV-2-positive (n = 7, 7.7%) and negative (n = 7, 6.6%) patients. Moreover, the frequency rate of viral infection was almost the same in both SARS-CoV-2-positive (18.68%) and negative (18.86%) patients. Altogether, there were no differences in baseline demographic characteristics such as age, sex, clinical symptoms, and comorbidities between the two groups (P > 0.05). Conclusions: The data presented here expand our understanding of the epidemiology of multiple types of viral respiratory pathogens in suspected COVID-19 patients. Therefore, simultaneous screening of other viral respiratory pathogens will be helpful for clinicians and researchers interested in the control of viral respiratory tract infections.

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“…Klebsiella pneumoniae is the main human pathogen causing infectious diseases over the past few decades [1]- [3], including pneumonia, urinary tract infections, bacteremia, and liver abscess [4]. In the hospital, the presence of K. pneumoniae is a major concern.…”

Section: Introductionmentioning

confidence: 99%

“…Patients with intensive care for a long period increase the risk factors for severe infections caused by K. pneumoniae [19]. Therefore, the intensive care room may become a place for the persistence and proliferation of drug-resistant microorganisms [3], [7], [20].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and diversity of ciprofloxacin-resistant Klebsiella pneumoniae clinical isolates

Sulistiyawati

Wahyono

Siswandari

2023

Proceeding ICMA-SURE

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The persistence and proliferation of multidrug-resistant microorganisms have the potential to occur in health centers and patient care units. WHO reports that cases of Klebsiella pneumoniae infection treated with ciprofloxacin in 34 countries have resistance from 4.1% to 79.4%. This study aimed to analyze the prevalence and diversity of ciprofloxacin-resistant K. pneumoniae from patients at Margono Soekardjo Hospital, Purwokerto. This study used a purposive sampling technique from blood, sputum, urine, pus, feces, and pleural fluid. The research process includes isolates characterization and identification, ciprofloxacin resistance testing, and its prevalence. This study recorded 99 cases of K. pneumoniae infection, and 48.5% of isolates were resistant to ciprofloxacin from August-September 2022. Biochemical and morphological tests showed a characteristic diversity of isolated K. pneumoniae against K. pneumoniae subspecies pneumoniae. The prevalence of ciprofloxacin-resistant K. pneumoniae was from blood (7.1%), sputum (59.6%), pus (23.2%), urine (6.1%), feces (3.03%), and pleural fluid (1.01%).

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Prevalence of Human Metapneumovirus Infections in Iran: A Systematic Review and Meta-Analysis

Cited by 6 publications

References 54 publications

The prevalence of 17 common respiratory viruses in patients with respiratory illness but negative for COVID‐19: A cross‐sectional study

The prevalence of 17 common respiratory viruses in patients with respiratory illness but negative for COVID‐19: A cross‐sectional study

Simultaneous Detection of Multiple Respiratory Viruses Among SARS-CoV-2-Positive and Negative Patients by Multiplex TaqMan One-Step Real-Time PCR

Prevalence and diversity of ciprofloxacin-resistant Klebsiella pneumoniae clinical isolates

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