Prevalence of hypercholesterolaemia among adults aged over 30 years in a rural area of north Kerala, India: a cross-sectional study

Aslesh, O. P.; Jayasree, A. K.; Karunakaran, Usha; Venugopalan, Anidil Kizhakinakath; Divakaran, Binoo; Mayamol, Thekkel Raghavannair; Sunil, Charappilli Bhaskaran; Minimol, Kizhakkedathu Joseph; Shalini, K; Mallar, Ganesh Bhagyanath; Sani, Thazhathe Peedika Mubarack

doi:10.4103/2224-3151.206557

Cited by 9 publications

(8 citation statements)

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“…Gender was not significantly associated with dyslipidemia in this study. However, findings in many previous studies reported that women had a significantly higher prevalence of dyslipidemia [ 15 – 17 , 26 , 30 ]. Whereas, contradictory findings were reported in China and Saudi Arabia [ 1 , 7 ].…”

Section: Discussionmentioning

confidence: 88%

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Angassa

Solomon

Seid

2022

BMC Cardiovasc Disord

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Background Dyslipidemia is a highly prevalent and modifiable risk factor for atherosclerotic cardiovascular diseases. Though the problem is significant in Ethiopia, available data in this regard is very poor among alcoholic beverage industrial workers. This study aimed to assess factors associated with dyslipidemia and its prevalence among Awash wine factory employees in Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted among 335 randomly selected employees of Awash wine factory, Addis Ababa, Ethiopia from January to February 2021. Data was collected by a face-to-face interview technique using the WHO STEPwise approach. Data were entered and analyzed using Epi Info 7 and SPSS version 26, respectively. Both bivariable and multivariable logistic regression analyses were performed to identify factors associated with dyslipidemia. All statistical tests were declared significant at p-value < 0.05. Results The overall prevalence of dyslipidemia was 67.8% (95% CI 62.5–72.7%). Elevated total cholesterol, elevated triglycerides, reduced high-density lipoprotein, and elevated low-density lipoprotein was found in 25.4%, 33.4%, 50.7%, and 21.5% of participants, respectively. Dyslipidemia was significantly associated with age group 30–39 years (AOR = 2.51; 95% CI 1.16–5.44, p = 0.019), ≥ 40 years (AOR = 6.45; 95% CI 2.01–20.71, p = 0.002), current alcohol consumption (AOR = 3.37; 95% CI 1.70–6.66, p < 0.001), eating vegetables < 2 days per week (AOR = 2.89; 95% CI 1.54–5.43, p = 0.001), sitting duration of > 4 h per day (AOR = 1.96; 95% CI 1.03–3.74, p = 0.041), and raised waist circumference (AOR = 4.56; 95% CI 2.07–10.08, p < 0.001). Conclusions High prevalence of dyslipidemia was found among Awash wine factory employees in Addis Ababa. Periodic screening of high-risk groups along with effective health promotion and education which encourages a healthy lifestyle is essential.

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Section: Discussionmentioning

confidence: 88%

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Angassa

Solomon

Seid

2022

BMC Cardiovasc Disord

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“…As claimed by Global Burden of Diseases report, 64 million cases of cardiovascular diseases were reported in India in the year 2015 causing demise of 3.4 million people out of which 61 million cases accounted for coronary heart diseases. Indians are more susceptible to hyperlipidemia and cardiovascular diseases that too at juvenescence because of the unsound nutritional habits like greater intake of unhealthy foods, an upsurge in sedentary lifestyle and increase in smoking and tobacco use (Aslesh et al 2016). In recent years, the propitious nutrient composition of oilseeds has fostered their utilization in development of multifarious products for prevention of metabolic diseases as well as for providing enhanced organoleptic properties to foods.…”

Section: Introductionmentioning

confidence: 99%

Lipid profile of hyperlipidemic males after supplementation of multigrain bread containing sunflower (Helianthus annuus) seed flour

Kaur

2020

J Food Sci Technol

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Sunflower seeds are produced and consumed worldwide due to their richness in heart friendly nutrients in the bakery products. Its effect on reducing the incidences of cardio vascular diseases have not been studied, through supplementary studies therefore present supplementation study was planned in which five samples of bread were prepared by using various multigrain flours and sunflower seed flour at five different levels of 2.5, 5, 7.5, 10 and 12.5%. The bread sample supplemented with 7.5% sunflower seed flour was found to be highly acceptable. Sunflower seeds were roasted at 60 °C for 10-15 min. Chemical analysis of sunflower seed flour (raw and roasted) and highly acceptable bread pertaining to proximate composition, in vitro protein digestibility, antioxidant activity, bioactive compounds, essential fatty acids and minerals was done using standard methods. Roasting of seeds resulted in significant increase in carbohydrates, protein digestibility, phosphorus, magnesium and copper contents. The most acceptable sample had good amount of energy (324.48 kcal), protein (10.61 g), fat (2.92 g), fibre (11.36 g), ash (3.29 g), antioxidant activity (12.13%), total phenols (31.54 mg), flavonoids (17.53 mg), omega 3 fatty acids (186.16 mg), omega 6 fatty acids (13,701.40 mg), phosphorus (68.74 mg), magnesium (28.13 mg) and copper (0.12 mg) per 100 g. Sixty hyperlipidemic males aged 30-50 years were supplemented with highly acceptable bread for four months. After the intervention period, mean daily intake of and nuts and oilseeds increased significantly (p \ 0.01) and a significant increase (p \ 0.01) in the intake of total fat, dietary fibre, PUFA, linoleic acid, ascorbic acid, alpha tocopherols and phosphorus was observed. The weight, BMI, total cholesterol, LDL cholesterol and triglycerides significantly reduced after the supplementation.

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“…Dyslipidemia is a condition of elevation in plasma lipids, includes triglycerides (TG), cholesterol, phospholipids along with plasma lipoproteins (VLDL, HDL, and LDL) 1 . Variety of cardiovascular diseases is one of the major deadly cause of fatality and mortality among the global population, which contribute to nearly one-fourth of the deaths in the age group of 25-65 years 2 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2020

IJPSR

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The aim of the present investigation was to formulate and evaluate phytoformulation prepared from the ethanolic extract of Vernonia elaeagnifolia. Vernonia elaeagnifolia whole plant was collected and extracted with ethanol by soxhlation. Dried ethanolic extract of Vernonia elaeagnifolia was used to formulate the nanosuspension by homogenization method to enhance the bioavailability of phytoconstituents by increasing its solubility. Nano suspension of Vernonia elaeagnifolia (NS-VE, 50 mg/kg, 100 mg/kg) was evaluated for particle size, polydispersed index (PDI), entrapment efficiency, zeta potential, Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC).NS-VE was screened for antihyperlipidemic activity with propylthiouracil induced and triton X-100 induced hyperlipidemia models in rats. The average particle size of NS-VE was found to be 0.027µm, PDI 60% (0.026 µm), 5mV zeta potential, and 46% entrapment efficiency. NS-VE (at doses 50 mg/kg, 100mg/kg bd.wt p.o) showed significant (p<0.01) antihyperlipidemic effect by reducing levels of TG, TC, LDL, VLDL and shown raised level in HDL when results were compared with normal control, disease control, and standard group. Nanosuspension of Vernonia elaeagnifolia can be used for the management of hyperlipidemia and other metabolic disorders with improved bioavailability.

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Prevalence of hypercholesterolaemia among adults aged over 30 years in a rural area of north Kerala, India: a cross-sectional study

Abstract: The prevalence of hypercholesterolaemia is high in the study population.

Cited by 9 publications

References 1 publication

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Lipid profile of hyperlipidemic males after supplementation of multigrain bread containing sunflower (Helianthus annuus) seed flour

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