Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review

Colosia, Ann; Palencia, R.; Khan, Shahnaz

doi:10.2147/dmso.s51325

Cited by 320 publications

(248 citation statements)

References 87 publications

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“…The same was shown in Nigeria [12], although the Nigerian study showed a higher rate of hypertension (60.9%). In Europe and Asia the prevalence of hypertension in diabetics was shown to be above 70% [13], which is also higher compared to what we found. The literature shows that high rates of microvascular complications in diabetics can be attributed to frequent high blood pressure [5].…”

Section: Resultscontrasting

confidence: 81%

Metabolic Deregulation Associated with Glycemic Imbalance In Gabonese Diabetics

Padzys¹,

Tiagni²,

Ngou-Milama³

et al. 2017

Diabetes Case Rep

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Aim: Diabetes is a metabolic disease most often associated with complications when uncontrolled. The present study aimed to investigate the relationship between diabetes-associated complications, glycemic imbalances and other metabolic deregulation in Gabonese diabetics.Methods: 115 known diabetics were recruited from the Libreville University hospital. We collected anthropometric data and information on associated pathologies. Blood samples collected were analyzed for blood glucose, urea, creatinine, triglycerides, cholesterol fractions and transaminases.Results: Type-2 diabetes was more prevalent in the studied population, representing 90% of cased cases. 41.7% had diabetes cases were associated with hypertension alone. 9.6% of diabetes cases had kidney failure (associated or not with hypertension and/or neuropathy). 87% patients had uncontrolled blood sugar. Creatinine and urea were significantly higher in patients with affections as compared to patients without affections (p<0.0001). In diabetics with controlled blood glucose concentration, only patients with the nephropathy had significantly high levels of creatinine and urea (p<0.05). In diabetics with uncontrolled blood glucose concentration, significantly high levels of creatinine and urea were seen in both patients with hypertension and patient with nephropathy (p<0.001). Conclusion:The high rate of hypertension and hyperglycemia observed suggest that Gabonese diabetics are at high risk for developing nephropathies.

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Section: Resultscontrasting

confidence: 81%

Metabolic Deregulation Associated with Glycemic Imbalance In Gabonese Diabetics

Padzys¹,

Tiagni²,

Ngou-Milama³

et al. 2017

Diabetes Case Rep

View full text Add to dashboard Cite

show abstract

“…Reports from Western countries show that the prevalence of obesity among diabetes patients has increased since the 1980s [17,18]. A review of diabetes patients showed that the prevalence of obesity, defined as BMI ≥30 kg/m 2 or waist circumference ≥102 cm in men and ≥88 cm in women, was 50.9-98.6% in Europe and 56.1% in Asia [2]. The percentage of Japanese patients with BMI ≥25 kg/m 2 was reported to be 33.9% in 2004 [19], which is similar to the findings from 2006 in our study.…”

Section: Discussionmentioning

confidence: 99%

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

et al. 2018

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Abstract. The prevalence of obesity is increasing globally in patients with diabetes. This study aimed to examine 12-year trends of increasing obesity in Japanese patients with diabetes, and their clinical features. The study used results of the Shiga Diabetes Clinical Survey, which recorded medical performance in diabetic patients in 2000, 2006 and 2012. Data were analyzed from 14,205, 14,407 and 21,449 adult patients in these three years, respectively. Overweight and obesity prevalence and the clinical features of diabetes patients were examined, stratified by body mass index (BMI) and age. The prevalence of overweight (BMI 25-30 kg/m 2 ) and obesity (BMI ≥30 kg/m 2 ) were 27.0% and 5.1% in 2000, 28.9% and 7.3% in 2006 and 30.9% and 10.0% in 2012. Glycemic control, blood pressure and serum lipid profile improved over 12 years in all BMI categories. However, glycemic and triglyceride control were insufficient in obese patients aged <65 years (hemoglobin A1c 7.5 ± 1.4%, triglyceride 197.7 ± 178.4 mg/dL in 2012). The percentage of patients who used antihypertensive and lipidlowering drugs increased and patients with higher BMI had increased frequency of using these drugs, both in young and old age groups. Higher BMI was significantly and positively associated with albuminuria. In summary, overweight and obesity have increased in Japanese diabetic patients, particularly for younger generations. Findings suggest that obesity may lead to poorer glycemic control, blood pressure and lipid profiles. Overweight and obesity are important modifiable risk factors for diabetes, suggesting that more active weight-control interventions are warranted.

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“…Type 2 Diabetes Mellitus (T2DM) and hypertension (HT) are common chronic disorders that often coexist [1]. Large epidemiological studies showed that the coexistence of elevated Blood Pressure (BP) in patients with T2DM is associated with increased risk of mortality and morbidity because of cardiovascular complications [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Factors Associated With Hypertension Prevalence and Control Among Lebanese Type 2 Diabetic Patients

Soubra

Nureddin

Omar

et al. 2016

Int J Pharm Pharm Sci

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Objective: The objectives of this study were to assess the prevalence of hypertension and the level of blood pressure (BP) control among a cohort of diabetic Lebanese patients on antihypertensive medications, as well as to identify factors associated with hypertension prevalence and uncontrolled BP. Methods:This cross-sectional retrospective study was conducted in a tertiary health care clinic that is specialized in the management and follow-up of diabetic outpatients.Results: Among the 700 type 2 diabetes mellitus patient files that were screened529 (75%) were found to have hypertension. Hypertension was more prevalent in women, patients aged ≥65-year-old, and those having a body mass index (BMI) of ≥30 (kg/m 2 Conclusion:Hypertension is prevalent among the study patients. However, attainment of BP control was poor among these patients. Therefore, there is a need for studies that determine reasons behind this low BP control rate in order to design interventions aiming at improving the standard of care for these patients.) (p-value<0.05). Among the hypertensive cohort, 465 T2DM were on antihypertensive medications and were included in the hypertension control analysis. Ninety-three patients (20%) attained BP control (SBP<140 and DBP<90 mmHg). Multivariate analyses revealed three factors that were significantly associated with uncontrolled BP control: Age being ≥65 y (adjusted OR = 1.96 (95% CI: 1.07-3.61, p-value<0.05), male gender (adjusted OR = 2.57, 95% CI: 1.41-4.66, p-value<0.05) and uncontrolled HDL (adjusted OR = 1.58, 95% CI: 1.33-2.01, p-value = 0.05).

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Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review

Cited by 320 publications

References 87 publications

Metabolic Deregulation Associated with Glycemic Imbalance In Gabonese Diabetics

Metabolic Deregulation Associated with Glycemic Imbalance In Gabonese Diabetics

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

Factors Associated With Hypertension Prevalence and Control Among Lebanese Type 2 Diabetic Patients

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