Prevalence of Hypertension During Pregnancy in Portugal

Póvoa, Ana Margarida; Costa, Fabíola; Rodrigues, Teresa; Patrı́cio, Belmiro; Cardoso, Filomena

doi:10.1080/10641950802000943

Cited by 20 publications

(22 citation statements)

References 6 publications

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“…In our study, the prevalence of hypertensive disorders during pregnancy was lower than reported in other industrialized nations (Bodnar et al, 2007;Gaillard et al, 2011;Roberts et al, 2005), and also slightly lower than the 5.6% previously described in a national survey for the Portuguese population (Povoa et al, 2008). Since the authors reported no significant differences in prevalence across the country (Povoa et al, 2008) we expected to find a similar prevalence. Despite the high proportion of participation in our cohort, it is possible that the refusals occurred mainly in cases with higher maternal and/or perinatal According to the Institute of Medicine recommendations (Rasmussen & Yaktine, 2009).…”

Section: Discussioncontrasting

confidence: 54%

“…Although this rate was lower than in other countries (Bodnar et al, 2007;Gaillard et al, 2011;Roberts et al, 2005), pre-term birth, small for gestational age newborns and foetal death were more frequent in women with hypertensive pregnancies (Povoa et al, 2008).…”

Section: Introductioncontrasting

confidence: 58%

“…In Portugal, a national survey conducted in 2005 estimated an overall prevalence of hypertensive disorders in pregnancy of 6% (Povoa et al, 2008). Although this rate was lower than in other countries (Bodnar et al, 2007;Gaillard et al, 2011;Roberts et al, 2005), pre-term birth, small for gestational age newborns and foetal death were more frequent in women with hypertensive pregnancies (Povoa et al, 2008).…”

Section: Introductionmentioning

confidence: 96%

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Impact of risk factors on hypertensive disorders in pregnancy, in primiparae and multiparae

Alves¹,

Azevedo²,

Rodrigues³

et al. 2013

Annals of Human Biology

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Section: Discussioncontrasting

confidence: 54%

Section: Introductioncontrasting

confidence: 58%

Section: Introductionmentioning

confidence: 96%

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Impact of risk factors on hypertensive disorders in pregnancy, in primiparae and multiparae

Alves¹,

Azevedo²,

Rodrigues³

et al. 2013

Annals of Human Biology

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“…The prevalence of the different hypertensive disorders in our study is largely in agreement with other reports. [21][22][23][24][25][26] Pre-eclampsia has been reported to complicate between 1.4% and 7% of all pregnancies, 13,21,22,24,27 and gestational hypertension between 1% and 4.3% of all pregnancies. 21,22,24,25 The prevalence of chronic hypertension varies between 0.2% and 5%, and the highest prevalence is among the oldest women.…”

Section: Discussionmentioning

confidence: 99%

Hypertensive disorders in pregnancy and fetal death at different gestational lengths: a population study of 2 121 371 pregnancies

Ahmad

Samuelsen

2012

BJOG

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Objective To compare the proportion of offspring that was stillborn in pregnancies with pre-eclampsia, gestational hypertension or chronic hypertension with those in normotensive pregnancies.Design Register-based observational study.Setting The Medical Birth Registry of Norway.Population All singleton births after 20 completed weeks of gestation in Norway from 1967 to 2006 (n = 2 121 371).Methods The proportion of stillborn offspring was estimated in normotensive pregnancies, and in pregnancies with pre-eclampsia, gestational and chronic hypertension at different gestational lengths. In addition, changes in the proportions of stillborn offspring by maternal hypertensive disorder from 1967-1986 to 1987-2006 were estimated. Main outcome measures Fetal death.Results The prevalence of hypertensive disorders in pregnancy was 4.7%. In total, 17 933 fetal deaths occurred and 9.2% of these were in hypertensive pregnancies. In normotensive pregnancies, 0.8% (16 290/2 022 400) experienced fetal death. This was true for 1.9% (1170/62 261) of the pregnancies with pre-eclampsia, 1.2% (390/32 068) with gestational hypertension and 1.8% (83/ 4642) with chronic hypertension. There was a 44% overall reduction in fetal death rate from 1967-1986 to 1987-2006. The largest decline was in women with pre-eclampsia (80% reduction). In women with gestational hypertension and chronic hypertension, the overall reductions in fetal death rates were 49% and 57%, respectively, comparable with the 41% decline in normotensive pregnancies.Conclusions In our nationwide study during 1967-2006, the risk of fetal death among women with hypertensive disorders in pregnancy has been greatly reduced, especially among preeclamptic women at term. The risk of fetal death among women with gestational or chronic hypertension has also decreased, but in a different manner.

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“…Antihypertensive drugs are routinely prescribed in pregnancy to reduce the progression to severe hypertension (systolic blood pressure of ≥160 mmHg). 1 Between 0.6% and 2% of women have chronic hypertension during pregnancy, [2][3][4][5][6] and an additional 6-7% develop hypertension during gestation. 7 Severe hypertension during pregnancy can lead to substantial morbidity for the mother and the fetus.…”

Section: Introductionmentioning

confidence: 99%

Prescription of antihypertensive medications during pregnancy in the UK

Soriano

Bateman

Rodrı́guez

et al. 2014

Pharmacoepidemiol Drug Saf

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Purpose To describe the management of antihypertensive medications in pregnancy by general practitioners in the United Kingdom (UK) and compare it with current guidelines. Methods We used electronic medical records from The Health Improvement Network (THIN) database from 1996-2010 to identify completed pregnancies. The study cohort included the first pregnancy identified during the study period in women aged 13-49. Information on both hypertension diagnoses and prescription of specific antihypertensive medications within the 90 days before the last menstrual period (LMP) and during pregnancy was ascertained from electronic medical records. Results Among 148,544 eligible pregnancies, we identified 1995 (1.3%) during which the women had pre-existing hypertension diagnosed by the LMP date. Overall, the prevalence of antihypertensive medications during the first trimester was 1.5%; beta-blockers were the most commonly prescribed antihypertensive. Among women with pre-existing hypertension, 36% were prescribed an antihypertensive medication during the 90 days before the LMP. Among those, 9.6 % and 22.2% had discontinued their medication by the first and second trimester, respectively. For contraindicated drugs such as angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARBs) the corresponding discontinuation rates were around 25% and 70%. Women who switched therapy received preferably either methyldopa or an alpha-beta blocker. Conclusions In this population of UK pregnant women, prescription patterns of antihypertensive medications were dominated by recommended treatments, although some patients continued on contraindicated drugs throughout pregnancy or switched to preferred agents in a delayed fashion.

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Prevalence of Hypertension During Pregnancy in Portugal

Abstract: In Portugal, the prevalence of hypertensive disorders diagnosed during pregnancy seems to be lower than that reported in most countries, but these disorders have a significant effect on pregnancy outcomes.

Cited by 20 publications

References 6 publications

Impact of risk factors on hypertensive disorders in pregnancy, in primiparae and multiparae

Impact of risk factors on hypertensive disorders in pregnancy, in primiparae and multiparae

Hypertensive disorders in pregnancy and fetal death at different gestational lengths: a population study of 2 121 371 pregnancies

Prescription of antihypertensive medications during pregnancy in the UK

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