Prevalence of hyperuricemia in Chitwan District of Nepal

Kumar, Sarvesh; Singh, AR; Takhelmayum, Roshan; Shrestha, Pragya; Sinha, JN

doi:10.3126/jcmsn.v6i2.3612

Cited by 10 publications

(11 citation statements)

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“…Research in China, Japan, Nepal, and Thailand reports that the incidence of increased uric acid is more common in men than in women. 1,[16][17][18] High uric acid levels are also often found in adults compared to adolescents and children. 18 This study done on Minangkabau ethnicity male.…”

Section: Discussionmentioning

confidence: 99%

Correlation nutritional status with uric acid level in Minangkabau men ethnicity

et al. 2018

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Background: Hyperuricemia is a predictor of metabolic syndrome influenced by many factors, one of which is nutritional status. A highly prevalence overweight and obesity in ethnic Minangkabau is quite high which can increase the prevalence of hyperuricemia. This study aims to determine the relationship of nutritional status intake with Minangkabau ethnic male uric acid levels.Methods: This study used a cross-sectional design, done in August to November 2016. Nutritional status was obtained through the measurement of body mass index (BMI) based on height and weight. The uric acid level examined in the Prodia laboratory. Data were analyzed by using chi-square test.Results: Most of subject were obesities. A total of 21% subjects suffers hyperuricemia. Statistic test results showed that there was a significant relationship between nutritional status and serum uric acid levels (p <0.0001).Conclusions: There was a significant relationship between nutritional status and serum uric acid levels in Minangkabau ethnic men in Padang city.

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Section: Discussionmentioning

confidence: 99%

Correlation nutritional status with uric acid level in Minangkabau men ethnicity

et al. 2018

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“…Hal ini menjelaskan mengapa peningkatan kadar asam urat pada wanita umumnya terjadi pada usia menopause. 14 Pada penelitian ini ditemukan 14 orang mahasiswa obes dan 8 orang mahasiswa non obes yang mengalami peningkatan kadar asam urat. Peningkatan kadar asam urat darah pada sampel ini sesuai dengan teori kemungkinan disebabkan oleh karena adanya penurunan ekskresi asam urat pada ginjal akibat resistensi insulin dan hiperinsulinemia yang terjadi pada keadaan berat badan lebih dan obesitas.…”

Section: Uji Statistikunclassified

Perbandingan Kadar Asam Urat Pada Subyek Obes Dan Non-Obes Di Fakultas Kedokteran Universitas Sam Ratulangi Manado

Rau¹,

Ongkowijaya²,

Kawengian³

2015

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Uric acid is the end product of purine metabolism. Circulating uric acid in the human body is produced by the body (endogenous uric acid) as well as derived from food (exogenous uric acid). Normal serum uric acid level is <7.0 mg / dL in men and <6.0 in women. Obesity can be defined as excess body fat. One of the markers used for body fat content is body mass index (BMI). This study aimed to compare the levels of uric acid in obese and non-obese subjects. This was an analytical study with a cross sectional design. The population is students of Faculty of Medicine University of Sam Ratulangi Manado. Samples were male students of batch 2013. There were 42 male students, consisted of 21 obese and 21 non-obese students. The results showed that the average of uric acid levels in obese group was 8.05 mg/dL and in non-obese group 6.63 mg/dL. In the obese group, 67% had an increase in uric acid level meanwhile in the non-obese group only 38%. The statistical test showed a sig 0,009. Conclusion: In this study, the average of uric acid level in obese group was significantly higher than in the non-obese group. However, there were students with either normal or high uric acid levels in both groups.Keywords: uric acid, obeseAbstrak: Asam urat merupakan produk akhir metabolisme purin. Asam urat yang beredar di dalam tubuh manusia di produksi sendiri oleh tubuh (asam urat endogen) dan berasal dari makanan (asam urat eksogen). Normalnya kadar asam urat serum <7,0 mg/dL pada pria dan <6,0 mg/dL pada wanita. Obesitas dapat di definisikan sebagai kelebihan lemak tubuh. Penanda kandungan lemak tubuh yang digunakan ialah indeks masa tubuh (IMT). Penelitian ini bertujuan untuk mengetahui perbandingan kadar asam urat pada subyek obes dan non obes. Penelitian ini bersifat analitik dengan pendekatan potong lintang. Populasi penelitian ialah mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Manado. Sampel idalah mahasiswa pria angkatan 2013 dan didapatkan 42 orang yang terbagi atas 21 obes dan 21 non obes. Hasil penelitian memperlihatkan rerata kadar asam urat pada obes 8,05 mg/dL dan pada non-obes 6,63 mg/dL. Peningkatan kadar asam urat ditemukan 67% pada kelompok obes dan 38% pada kelompok non-obes. Uji statistik menunjukkan nilai sig 0,009. Simpulan: Pada penelitian ini rerata kadar asam urat pada kelompok obes lebih tinggi secara bermakna daripada kelompok non-obes. Walaupun demikian, pada kedua kelompok ditemukan mahasiswa dengan kadar asam urat normal maupun meningkat.Kata kunci: asam urat, obesitas

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“…Sehingga pada keadaan hiperinsulinemia pada pra diabetes terjadi peningkatan reabsorbsi yang akan menyebabkan hiperurisemia. 15,16 Studi oleh Pasifico EL et al tahun 2009 pada anak dan remaja menemukan bahwa hiperurisemia berhubungan erat dengan obesitas, lebih khusunya penderita sindroma metabolik. Selain itu, hiperurisemia berhubungan erat dengan jenis kelamin laki-laki dan pertambahan usia.…”

Section: Bahasanunclassified

Hubungan Antara Kadar Asam Urat Dengan Tekanan Darah Pada Mahasiswa Pria Obesitas Sentral Fakultas Kedokteran Universitas Sam Ratulangi Manado

Mansur¹,

Wantania²,

Surachmanto³

2015

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Inflammation plays an important role in hypertension process and central obesity. Recent studies found that hyperuricemia was also related to inflammation. This study aimed to find out the relation between uric acid level with blood pressure among central-obese-male students in the Faculty of Medicine Unsrat. Methods: This was an analytical study with a cross section design. There were 37 people as samples. Data were obtained by measuring the waist size, blood pressure, and uric acid. The data were analyzed with the Statistical Product and Service Solution (SPSS) and Pearson correlation test. The results showed that most respondents were 19 years old (12 respondents, 32.4%) and the lowest were 17, 22 and 23 years old, each of them was 1 person (2.7%). The mean systolic blood pressure was 130.54 mmHg (SD ± 10.259). The mean diastolic blood pressure was 88.11 mmHg (SD ± 7.760). The mean level of uric acid was 7.514 mg/dL (SD ± 1.65). This study showed that there was some significant relation between the systolic blood pressure and uric acid level (p=0.019), as well as between the diastolic blood pressure and uric acid level (p=0.022). Conclusion: There was a significant correlation between the uric acid level and blood pressure in male students with central obesity.Keywords: obesity, uric acid, blood pressureAbstrak: Inflamasi berperan penting dalam proses terjadinya hipertensi dan obesitas sentral. Pada penelitian terkini ditemukan bahwa hiperurisemia juga berhubungan dengan proses inflamasi. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar asam urat dengan tekanan darah pada mahasiswa pria obesitas sentral Fakultas Kedokteran Unsrat. Penelitian ini bersifat analitik menggunakan rancangan potong lintang dengan sampel berjumlah 37 orang. Data diperoleh melalui pemeriksaan lingkar perut, tekanan darah, dan asam urat. Data dianalisis dengan menggunakan Statistical Product and Service Solution (SPSS) dan uji Pearson correlation. Hasil penelitian memperlihatkan bahwa sebagian besar responden berada pada kategori umur 19 tahun (12 responden, 32,4%) dan terendah umur 17, 22, dan 23 tahun masing-masing sejumlah 1 orang (2,7%). Berdasarkan nilai mean dapat dilihat bahwa rerata tekanan darah sistol 130,54 mmHg (SD ± 10,259). Rerata tekanan darah diastol 88,11 mmHg (SD ± 7,760). Rerata kadar asam urat responden 7,514 mg/dL (SD ± 1,65). Hasil penelitian menunjukkan secara statistik terdapat hubungan yang bermakna, baik antara tekanan darah sistol dan asam urat (p=0,019) maupun antara tekanan darah diastol dan kadar asam urat (p=0,022). Simpulan: Terdapat hubungan bermakna antara kadar asam urat dan tekanan darah pada mahasiswa pria obesitas sentral.Kata kunci: obesitas, asam urat, tekanan darah

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Prevalence of hyperuricemia in Chitwan District of Nepal

Cited by 10 publications

References 0 publications

Correlation nutritional status with uric acid level in Minangkabau men ethnicity

Correlation nutritional status with uric acid level in Minangkabau men ethnicity

Perbandingan Kadar Asam Urat Pada Subyek Obes Dan Non-Obes Di Fakultas Kedokteran Universitas Sam Ratulangi Manado

Hubungan Antara Kadar Asam Urat Dengan Tekanan Darah Pada Mahasiswa Pria Obesitas Sentral Fakultas Kedokteran Universitas Sam Ratulangi Manado

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