Prevalence of hypovitaminosis D and its association with oral lesions in HIV-infected Brazilian adults

Abstract

Introduction:This study assessed the prevalence of hypovitaminosis D and its association with oral candidiasis and clinical parameters of periodontitis (CPP) in HIV-infected patients. Methods: Periodontal examinations for the 113 HIV-infected patients were recorded using the Community Periodontal Index. A cytological smear from the lateral borders of the tongue was performed to evaluate candidiasis. Results: The frequency of hypovitaminosis D was 23.9%. In multivariate analysis, only the duration of exposure to HIV was associated with CPP .00)]. Conclusions: The prevalence of hypovitaminosis D was 23.9% and was not related with oral candidiasis or CPP.

Vitamin D levels and risk for periodontal disease: A systematic review

“…Another study evaluated an Indonesian population and found that 25(OH)D levels were not correlated with ABL . A study conducted in HIV‐infected Brazilian adults that analyzed the correlation of 25(OH) levels with Community Periodontal Index criteria also did not find significant associations …”

“…Ten studies evaluated samples from the general population, 3 studies included only older men, 4 studies assessed exclusively post‐menopausal women and 2 included older women . Other studies evaluated patients with specific health conditions (pregnant women, hospital patients, breast cancer survivors, HIV‐infected adults, liver transplant patients) …”

“…The definition of vitamin D status differed among the studies and was based on dietary intake/supplementation use of vitamin D or on serum levels of 25(OH)D or 1,25(OH) 2 D . Vitamin D serum levels were statistically analyzed using a variety of methods: 6 studies applied the mean serum 25(OH)D as a continuous variable; 4 divided the sample in quintiles of serum 25(OH)D; and 10 used some established criteria to determine the vitamin D status of individuals.…”

“…In total, 13 (65%) of the 20 cross‐sectional and case‐control studies found statistically significant associations between lower vitamin D levels and poor periodontal conditions . Seventeen of them evaluated serum levels of vitamin D …”

“…Other 6 studies were conducted in individuals with specific health conditions . A case‐control study in chronic obstructive pulmonary disease patients found that lower levels of 25(OH)D were associated with poor periodontal parameters .…”