2020
DOI: 10.21203/rs.3.rs-136139/v1
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Prevalence of IGFBP3, NOS3 and TCF7L2 Polymorphisms and Their Association With Hypertension: A Population-Based Study With Brazilian Women of African Descent

Abstract: Background: African ancestry seems to be a risk factor for hypertension; however, few genetic studies have addressed this issue. This study aimed to investigate the prevalence of polymorphisms NOS3; rs1799983, IGFBP3; rs11977526 and TCF7L2; rs7903146 in Brazilian women of African descent and their association with hypertension.Methods: This is a cross-sectional study with a sample of 1021 women (19–59 years old) from the quilombola communities of Alagoas (Brazil). Demographic, socioeconomic, lifestyle, anthrop… Show more

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“…The variables obtained were: women's color/race, education of women and head of household (27), monthly family income per capita (in number of minimum wages), number of rooms in the residence (>4 or ≤ 4) (28), construction type (masonry or other), house occupation (own or not), whether there are children or adolescents in the family (yes; no), garbage collection (public or not), number of people per household (>4 or ≤ 4) (28), source of water for general use in the house (piped or not), drinking water (piped/mineral or other), and whether the women had hypertension. The diagnosis of hypertension followed the same protocol described by Lira (29).…”
Section: Data Collectionmentioning
confidence: 99%
“…The variables obtained were: women's color/race, education of women and head of household (27), monthly family income per capita (in number of minimum wages), number of rooms in the residence (>4 or ≤ 4) (28), construction type (masonry or other), house occupation (own or not), whether there are children or adolescents in the family (yes; no), garbage collection (public or not), number of people per household (>4 or ≤ 4) (28), source of water for general use in the house (piped or not), drinking water (piped/mineral or other), and whether the women had hypertension. The diagnosis of hypertension followed the same protocol described by Lira (29).…”
Section: Data Collectionmentioning
confidence: 99%