2001
DOI: 10.1016/s0002-9149(00)01378-3
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Prevalence of isolated left ventricular diastolic dysfunction in hypertension as assessed by combined transmitral and pulmonary vein flow Doppler study

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Cited by 27 publications
(8 citation statements)
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“…In the present study, we found an association of GD1 with prolonged deceleration time of transmitral E velocity and greater AFF, resembling the pattern of LV abnormal relaxation, which is typical in uncomplicated hypertensive patients. [22][23][24] Despite not statistically significant, the differences in both transmitral E velocity and mitral annular e 0 velocity were also concordant with this analysis, since their averages were substantially lower in GD1 (mean age 46.4 AE 10.2 years) in comparison with both normal controls of our population and the normal values of the decades of age 41-60 years-the most represented in our population-described in previous studies. 14 The age dependence of pulsed tissue Doppler parameters is well known.…”
Section: Discussionsupporting
confidence: 91%
“…In the present study, we found an association of GD1 with prolonged deceleration time of transmitral E velocity and greater AFF, resembling the pattern of LV abnormal relaxation, which is typical in uncomplicated hypertensive patients. [22][23][24] Despite not statistically significant, the differences in both transmitral E velocity and mitral annular e 0 velocity were also concordant with this analysis, since their averages were substantially lower in GD1 (mean age 46.4 AE 10.2 years) in comparison with both normal controls of our population and the normal values of the decades of age 41-60 years-the most represented in our population-described in previous studies. 14 The age dependence of pulsed tissue Doppler parameters is well known.…”
Section: Discussionsupporting
confidence: 91%
“…Reduction of LA volumes plays an important role in the normalization of diastolic filling, implying that LV hypertrophy is associated with elevated LV end-diastolic pressure and that regression of hypertrophy reduced LV end-diastolic pressure and the grade of diastolic dysfunction. Diastolic dysfunction occurs early in hypertension, even before detectable LV hypertrophy [28]. To estimate dysfunction, it is useful to integrate the analysis of mitral inflow pattern with pulmonary vein flow pattern.…”
Section: Discussionmentioning
confidence: 99%
“…A alteração da função diastólica é frequente nos portadores de hipertensão arterial sistêmica. Tal fato é relacionado ao aumento do colágeno intersticial e à hipertrofia miocárdica secundária ao aumento da pós carga cardíaca [8][9][10] . Como a hipertensão arterial sistêmica é uma condição que coexiste frequentemente em idosos, a correta discriminação da presença de disfunção diastólica discreta se constitui um desafio, pois a maior parte dos parâmetros ecocardiográficos apresentam influência da idade.…”
Section: Discussionunclassified
“…A hipertensão arterial sistêmica está frequentemente associada à disfunção diastólica 8,9 , com alguns estudos revelando prevalência maior que 50% de alterações da função diastólica em pacientes hipertensos 10 . O aumento crônico da pós carga cardíaca é um importante estímulo para a ocorrência de alterações como o remodelamento e hipertrofia miocárdica, além do aumento do colágeno intersticial, resultando em maior rigidez e piora do relaxamento ventricular.…”
Section: Introductionunclassified
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