Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study

Yoshimura, Nagahisa; Muraki, Shigeyuki; Oka, Hiroyuki; Mabuchi, Akihiko; Enyo, Yoshio; Yoshida, Munehito; Saika, Akihiko; Yoshida, Hideyo; Suzuki, Takao; Yamamoto, Seiji; Ishibashi, Hiroyuki; Kawaguchi, Hiroshi; Nakamura, Kozo; Akune, Toru

doi:10.1007/s00774-009-0080-8

Cited by 704 publications

(486 citation statements)

References 14 publications

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“…The incidence of vertebral fractures and arthritic deformities increases with age; however, only fractures are related to low aBMD. (25,26) High-trauma vertebral fractures and Scheuerman disease are more frequent in men than in women, whereas the reverse is the case for the osteoporotic vertebral fracture. (27,28) Vertebral fractures are a hallmark of osteoporosis.…”

Section: Discussionmentioning

confidence: 99%

Cross-sectional analysis of the association between fragility fractures and bone microarchitecture in older men: The STRAMBO study

Szulc

Boutroy

Vilayphiou

et al. 2010

Journal of Bone and Mineral Research

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Areal bone mineral density (aBMD) measured by dual-energy X-ray absorptiometry (DXA) identifies 20% of men who will sustain fragility fractures. Thus we need better fracture predictors in men. We assessed the association between the low-trauma prevalent fractures and bone microarchitecture assessed at the distal radius and tibia by high-resolution peripheral quantitative computed tomography (HRpQCT) in 920 men aged 50 years of older. Ninety-eight men had vertebral fractures identified on the vertebral fracture assessment software of the Hologic Discovery A device using the semiquantitative criteria, whereas 100 men reported low-trauma peripheral fractures. Men with vertebral fractures had poor bone microarchitecture. However, in the men with vertebral fractures, only cortical volumetric density (D.cort) and cortical thickness (C.Th) remained significantly lower at both the radius and tibia after adjustment for aBMD of ultradistal radius and hip, respectively. Low D.cort and C.Th were associated with higher prevalence of vertebral fractures regardless of aBMD. Severe vertebral fractures also were associated with poor trabecular microarchitecture regardless of aBMD. Men with peripheral fractures had poor bone microarchitecture. However, after adjustment for aBMD, all microarchitectural parameters became nonsignificant. In 15 men with multiple peripheral fractures, trabecular spacing and distribution remained increased after adjustment for aBMD. Thus, in men, vertebral fractures and their severity are associated with impaired cortical bone, even after adjustment for aBMD. The association between peripheral fractures and bone microarchitecture was weaker and nonsignificant after adjustment for aBMD. Thus bone microarchitecture may be a determinant of bone fragility in men, which should be investigated in prospective studies. ß

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Section: Discussionmentioning

confidence: 99%

Cross-sectional analysis of the association between fragility fractures and bone microarchitecture in older men: The STRAMBO study

Szulc

Boutroy

Vilayphiou

et al. 2010

Journal of Bone and Mineral Research

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“…In fact, the prevalence of orthopedic diseases has been shown to be higher than expected [14,15]. The early consultation with a specialist will lead to increased opportunities for the proper treatment at an earlier stage of disease.…”

Section: Open Accessmentioning

confidence: 99%

Utility of “loco-check,” self-checklist for “locomotive syndrome” as a tool for estimating the physical dysfunction of elderly people

Matsui¹,

Takemura²,

Harada³

et al. 2013

Health

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Aim: A new concept of locomotive syndrome has been proposed by the Japanese Orthopaedic Association. The aim of this study is to clarify the utility of its self-checklist, "loco-check," as a tool for estimating the physical dysfunction of elderly people. Methods: Subjects were 1124 community-dwelling Japanese people, 557 men and 567 women, aged 40 -89 years. Information about the seven "loco-check" items was obtained from present inquiry sheets. Physical functions were examined by grip strength, knee extension strength, walking speed and one-leg standing time with open eyes. The averages of these test values, controlled for age and BMI, were compared between the "loco-check" (+) group and the "loco-check" (−) group. Also we examined about the trend of decline of physical function, together with SF36 physical function subscale score, as the number of the items chosen increased. Results: Adjusted average values of all four physical function examinations in the "lococheck" (+) group were significantly lower than those of the "loco-check" (−) group (all, p < 0.001). Also the adjusted average values of the majority of four tests were significantly lower in those who checked each of the "lococheck" items than those who did not, for most of the items. It was also revealed that the more items subjects checked, the lower the adjusted average values were, except for one-leg standing time. It was also the case with SF36 physical function subscale score. Conclusion: We showed the utility of "loco-check" as a simple tool not only for noticing the physical dysfunction of elderly people, but also for estimating the extent of it, except for balancing ability, particularly by counting the number of checked items.

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“…Osteoarthritis (OA) is one of the most common disorders affecting elderly populations, and causes chronic pain and disability (1,2). Pain during knee OA derives from several different mechanisms in the involved joints, such as loading pain in the femorotibial joint and anterior knee pain related to contraction of the quadriceps muscle in the patellofemoral joint.…”

Section: Introductionmentioning

confidence: 99%

Nocturnal Knee Pain Increases With the Severity of Knee Osteoarthritis, Disturbing Patient Sleep Quality

Sasaki

Tsuda

Yamamoto

et al. 2014

Arthritis Care & Research

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Objective. Sleep disturbances frequently accompany chronic pain from osteoarthritis (OA). Effective management of sleep disturbances may require successful treatment of chronic pain, a key factor in the clinical evaluation of knee OA. However, the relationship between the severity of knee OA and sleep quality is unclear. Our purpose was to correlate the prevalence of nocturnal knee pain with different OA severity levels and to determine its influence on sleep quality. Methods. Subjects included 1,214 local volunteers with mean ؎ SD age 58.1 ؎ 13.0 years. The existence and severity of knee OA were determined by the Kellgren/Lawrence (K/L) grade, and joint space widths were measured. The presence of nocturnal knee pain and Knee Injury and Osteoarthritis Outcome Scores (KOOS) were assessed by self-completed questionnaires. Sleep quality was evaluated by the Pittsburgh Sleep Quality Index. Knee-related factors affecting sleep quality were detected using statistical methods. Results. The prevalence of nocturnal knee pain was 3.6%, 6.9%, 19.4%, 32.7%, and 75.0% in K/L grades 0, 1, 2, 3, and 4, respectively. Also, prevalence significantly increased with OA severity (P < 0.001). Sleep problems also increased with K/L grade (P ‫؍‬ 0.038), and KOOS quality of life (QOL) was significantly lower in those with OA and sleep problems. Logistic regression showed that sleep problems were related to joint space narrowing (P ‫؍‬ 0.016) and nocturnal knee pain (P ‫؍‬ 0.039). Severe OA also disturbed onset and maintenance of sleep. Conclusion. The prevalence of nocturnal knee pain and sleep problems increased with the severity of OA, impacting QOL. These results suggest the necessity of appropriate nocturnal pain control.

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Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study

Cited by 704 publications

References 14 publications

Cross-sectional analysis of the association between fragility fractures and bone microarchitecture in older men: The STRAMBO study

Cross-sectional analysis of the association between fragility fractures and bone microarchitecture in older men: The STRAMBO study

Utility of “loco-check,” self-checklist for “locomotive syndrome” as a tool for estimating the physical dysfunction of elderly people

Nocturnal Knee Pain Increases With the Severity of Knee Osteoarthritis, Disturbing Patient Sleep Quality

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